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Zafran Khan

Bio: Zafran Khan is an academic researcher from Guangzhou Institutes of Biomedicine and Health. The author has contributed to research in topics: Virology & Medicine. The author has an hindex of 3, co-authored 7 publications receiving 29 citations. Previous affiliations of Zafran Khan include Chinese Academy of Sciences & University of Swat.

Papers
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Journal ArticleDOI
04 Mar 2021
TL;DR: Precautionary measures should be ensured to protect the community from the possible risk associated with disinfectants against COVID-19, and children are considered more prone to alcohol poisoning and other major health concern.
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan city of China in late December 2019 and identified as a novel coronavirus disease 2019 (COVID-19). On January 30, the World Health Organization (WHO) declared the coronavirus outbreak a global public health emergency. The rapid spread of the pathogen across the communities shock the entire population. As no existing therapy were available during the pandemic. Health professionals recommended frequent washing of hands with soap and alcohol-based sanitizers. Disinfectants were extensively sprayed to minimize the possibility of getting COVID-19. Despite the potential benefits of these germicidal agents against COVID-19. Alcohol-based hand sanitizers lead to dry skin, infection, and alcohol poisoning. Children are considered more prone to alcohol poisoning and other major health concern. Precautionary measures should be ensured to protect the community from the possible risk associated with disinfectants.

74 citations

Journal ArticleDOI
TL;DR: A list of drugs used to treat COVID-19 for instance, dexamethasone, chloroquine, hydroxychloroquines, lopinavir/ritonavir, favipirvir, remdesivir, tociluzimab, nitazoxanide, and ivermectin are collected.
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan city of China in late December 2019 and identified as a novel coronavirus. Due to its contagious nature, the virus spreads rapidly and causes coronavirus disease 2019 (COVID-19). The global tally of COVID-19 spikes 28 million. The fears and stress associated with SARS- CoV-2 demolished the socio-economic status all over the world. Researchers are trying around the clock to find out the treatment especially antiviral drugs and/or vaccines that could potentially control the viral spread and manage the ongoing unprecedented global crises. To date, more than 300 clinical trials have been conducted on various antiviral drugs, and immunomodulators are being evaluated at various stages of COVID-19. This review is aimed to collect and summarize a list of drugs used to treat COVID-19 for instance, dexamethasone, chloroquine, hydroxychloroquine, lopinavir/ritonavir, favipiravir, remdesivir, tociluzimab, nitazoxanide, and ivermectin. However, some of these drugs are not effective and suspended by the WHO (World Health Organization).

13 citations

Journal ArticleDOI
TL;DR: In this article, the authors emphasized the potential role of PMs in the spread of COVID-19, and the relationship among COVID19, PMs, and angiotensin-converting enzyme 2 (ACE2) was also summarized.
Abstract: Air pollution (AP) is one of the leading causes of health risks because it causes widespread morbidity and mortality every year. Its impact on the environment includes acid rain and decreased visibility, but more importantly, it also has an impact on human health. The rise of COVID-19 demonstrates the cost of failing to manage AP. COVID-19 can be spread through the air, and atmospheric particulate matters (PMs) can create a good atmosphere for the long-distance spread of the virus. Moreover, these PMs can cause lung cell inflammation, thereby increasing sensitivity and the severity of symptoms in COVID-19 patients. In this study, we emphasized the potential role of PMs in the spread of COVID-19. The relationship among COVID-19, PMs, and angiotensin-converting enzyme 2 (ACE2) (receptor involved in virus entry into lung cells and inflammation) was also summarized.

12 citations

Journal ArticleDOI
TL;DR: Guillain-Barre syndrome (GBS) has been linked previously to several viral or bacterial infections, and the finding of GBS after vaccination with certain COVID-19, while rare, should alert medical practitioners for an early diagnosis and targeted treatment as mentioned in this paper .

5 citations

Journal Article
TL;DR: No positive significant mid-parent heterosis was observed for the parameters like fruit length and fruit size or better parent heterosis regarding yield and yield related traits in different cross combinations of tomato.
Abstract: The purpose ofconducting present study was to evaluate the performance of different cross combinations of tomato for mid parent heterosis and better parent heterosis regarding yield and yield related traits. Forthe parameters: No of fruits/clusters, No of fruits/plants, Fruitweight, plant height and yield/plant,some of the combinations showed significant positive mid parent heterosis. No positive significant mid-parent heterosis was observed for the parameters like fruit length and fruit size. Significant better-parent heterosis was observed in some cross-combinations for the parameters: No of fruits/clusters, No of fruits/plants and yield/plant. While, no significant positive heterosis was observed for the parameters like fruit-length, fruit diameter,fruit size and fruit weight. For fruit length and fruit diameter all the combinations showed negative value of heterosis. Significant positive heterosis for yield/plant is great achievement in our study as yield/plant is the ultimate goal of tomato growers.

5 citations


Cited by
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01 Jan 1999

202 citations

Journal ArticleDOI
TL;DR: It is concluded that there is a significant association between chronic exposure to various outdoor air pollutants: PM2.5, PM10, O3, NO2, SO2 and CO, and the incidence/risk of COVID-19 cases, as well as the severity/mortality of the disease.

89 citations

Journal ArticleDOI
TL;DR: In this article , a review focused on assessing the influence of various air pollutants on the transmission of SARS-CoV-2, and the severity of COVID-19 in patients infected by the coronavirus.
Abstract: In June 2020, we published a review focused on assessing the influence of various air pollutants on the transmission of SARS-CoV-2, and the severity of COVID-19 in patients infected by the coronavirus. The results of most of those reviewed studies suggested that chronic exposure to certain air pollutants might lead to more severe and lethal forms of COVID-19, as well as delays/complications in the recovery of the patients. Since then, a notable number of studies on this topic have been published, including also various reviews. Given the importance of this issue, we have updated the information published since our previous review. Taking together the previous results and those of most investigations now reviewed, we have concluded that there is a significant association between chronic exposure to various outdoor air pollutants: PM2.5, PM10, O3, NO2, SO2 and CO, and the incidence/risk of COVID-19 cases, as well as the severity/mortality of the disease. Unfortunately, studies on the potential influence of other important air pollutants such as VOCs, dioxins and furans, or metals, are not available in the scientific literature. In relation to the influence of outdoor air pollutants on the transmission of SARS-CoV-2, although the scientific evidence is much more limited, some studies point to PM2.5 and PM10 as potential airborne transmitters of the virus. Anyhow, it is clear that environmental air pollution plays an important negative role in COVID-19, increasing its incidence and mortality.

81 citations

Journal ArticleDOI
TL;DR: In this paper, the role of disinfectants and sanitizers in the control and prevention of the current pandemic and highlights updated disinfection techniques against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Abstract: Disinfectants and sanitizers are essential preventive agents against the coronavirus disease 2019 (COVID-19) pandemic; however, the pandemic crisis was marred by undue hype, which led to the indiscriminate use of disinfectants and sanitizers. Despite demonstrating a beneficial role in the control and prevention of COVID-19, there are crucial concerns regarding the large-scale use of disinfectants and sanitizers, including the side effects on human and animal health along with harmful impacts exerted on the environment and ecological balance. This article discusses the roles of disinfectants and sanitizers in the control and prevention of the current pandemic and highlights updated disinfection techniques against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This article provides evidence of the deleterious effects of disinfectants and sanitizers exerted on humans, animals, and the environment as well as suggests mitigation strategies to reduce these effects. Additionally, potential technologies and approaches for the reduction of these effects and the development of safe, affordable, and effective disinfectants are discussed, particularly, eco-friendly technologies using nanotechnology and nanomedicine.

75 citations

Journal ArticleDOI
04 Mar 2021
TL;DR: Precautionary measures should be ensured to protect the community from the possible risk associated with disinfectants against COVID-19, and children are considered more prone to alcohol poisoning and other major health concern.
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan city of China in late December 2019 and identified as a novel coronavirus disease 2019 (COVID-19). On January 30, the World Health Organization (WHO) declared the coronavirus outbreak a global public health emergency. The rapid spread of the pathogen across the communities shock the entire population. As no existing therapy were available during the pandemic. Health professionals recommended frequent washing of hands with soap and alcohol-based sanitizers. Disinfectants were extensively sprayed to minimize the possibility of getting COVID-19. Despite the potential benefits of these germicidal agents against COVID-19. Alcohol-based hand sanitizers lead to dry skin, infection, and alcohol poisoning. Children are considered more prone to alcohol poisoning and other major health concern. Precautionary measures should be ensured to protect the community from the possible risk associated with disinfectants.

74 citations