Z
Zanjing Zhai
Researcher at Shanghai Jiao Tong University
Publications - 68
Citations - 2147
Zanjing Zhai is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Osteoclast & Bone resorption. The author has an hindex of 26, co-authored 58 publications receiving 1670 citations.
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Journal ArticleDOI
Biodegradable Mg-Cu alloy implants with antibacterial activity for the treatment of osteomyelitis: In vitro and in vivo evaluations.
Yang Li,Lina Liu,Peng Wan,Zanjing Zhai,Zhenyang Mao,Zhengxiao Ouyang,Degang Yu,Qi Sun,Lili Tan,Ling Ren,Zhenan Zhu,Yongqiang Hao,Xinhua Qu,Ke Yang,Kerong Dai +14 more
TL;DR: The results indicate the potential utility of Mg-Cu alloy implants with 0.25 wt% Cu in treating orthopedic infections, with favorable biocompatibility.
Journal ArticleDOI
The effect of metallic magnesium degradation products on osteoclast-induced osteolysis and attenuation of NF-κB and NFATc1 signaling.
Zanjing Zhai,Xinhua Qu,Haowei Li,Ke Yang,Peng Wan,Lili Tan,Zhengxiao Ouyang,Xuqiang Liu,Bo Tian,Fei Xiao,Wengang Wang,Chuan Jiang,Tingting Tang,Qiming Fan,An Qin,Kerong Dai +15 more
TL;DR: This study suggests that metallic magnesium, one of the orthopedic implants with superior properties, has significant potential for the treatment of osteolysis-related diseases caused by excessive osteoclast formation and function.
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Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo.
Zanjing Zhai,Huiwu Li,Guangwang Liu,Xinhua Qu,Bo Tian,W Yan,Zhen Lin,Zhen Lin,Tingting Tang,An Qin,An Qin,Kerong Dai +11 more
TL;DR: Changes in osteoclastogenesis and LPS‐induced osteolysis in response to andrographolide (AP), a diterpenoid lactone isolated from the traditional Chinese and Indian medicinal plant Andrographis paniculata are examined.
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Meta-Analysis of Sonication Fluid Samples from Prosthetic Components for Diagnosis of Infection after Total Joint Arthroplasty
Zanjing Zhai,Huiwu Li,An Qin,Guangwang Liu,Xuqiang Liu,Chuanlong Wu,Zhenan Zhu,Xinhua Qu,Kerong Dai +8 more
TL;DR: SFC has high sensitivity and very high specificity for diagnosing PJI and the best SFC cutoff was ≥5 CFU, according to a meta-analysis of 12 studies that evaluated sonication fluid cultures for the diagnosis of prosthetic joint infection.
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The effect of enoxacin on osteoclastogenesis and reduction of titanium particle-induced osteolysis via suppression of JNK signaling pathway.
Xuqiang Liu,Xinhua Qu,Chuanlong Wu,Zanjing Zhai,Bo Tian,Haowei Li,Zhengxiao Ouyang,Xinchen Xu,Wengang Wang,Qiming Fan,Tingting Tang,An Qin,Kerong Dai +12 more
TL;DR: The results suggest that enoxacin, an antibiotic with few side effects that is widely used in clinics, had significant potential for the treatment of particle-induced peri-implant osteolysis and other diseases caused by excessive osteoclast formation and function.