scispace - formally typeset
Search or ask a question
Author

Zhaoguang Liang

Bio: Zhaoguang Liang is an academic researcher from Harbin Medical University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 9 publications receiving 243 citations.

Papers
More filters
Journal ArticleDOI
TL;DR: Remote‐controlled catheter navigation systems have recently been introduced into minimally invasive vascular surgery and some of them have already been applied in clinical practice.
Abstract: Background Remote-controlled catheter navigation systems have recently been introduced into minimally invasive vascular surgery and some of them have already been applied in clinical practice. Steerable catheters with improved manoeuvrability play an important role in these innovations for conventional catheterization. Methods This review details the development of various steerable catheters, both in use clinically and under investigation. Comprehensive comparison and analysis in several key aspects are followed to reveal both the advantages and limitations of these catheters, as well as the requirements for relevant techniques. Results Steerable catheters are able to select direction in the distal end, and superior to conventional counterparts in many aspects. Differences between magnetic and active catheters mainly lie in function, safety, configuration of operating room and cost. They have similar requirements for miniaturization and slave insertion mechanisms. Conclusions Steerable catheters are rapidly evolving and still require technological refinements to extend current capabilities. Copyright © 2009 John Wiley & Sons, Ltd.

140 citations

Journal ArticleDOI
TL;DR: The emergence of the active catheter has prompted the development of catheterization in minimally invasive surgery, however, it is still operated using only the physician's vision; information supplied by the guiding image and tracking sensors has not been fully utilized.
Abstract: Background The emergence of the active catheter has prompted the development of catheterization in minimally invasive surgery. However, it is still operated using only the physician's vision; information supplied by the guiding image and tracking sensors has not been fully utilized. Methods In order to supply the active catheter with more useful information for automatic navigation, we extract the skeleton of blood vessels by means of an improved distance transform method, and then present the crucial geometric information determining navigation. With the help of tracking sensors' position and pose information, two operations, advancement in the proximal end and direction selection in the distal end, are alternately implemented to insert the active catheter into a target blood vessel. Results The skeleton of the aortic arch reconstructed from slice images is extracted fast and automatically. A navigation path is generated on the skeleton by manually selecting the start and target points, and smoothed with the cubic cardinal spline curve. Crucial geometric information determining navigation is presented, as well as requirements for the catheter entering the target blood vessel. Using a shape memory alloy active catheter integrated with magnetic sensors, an experiment is carried out in a vascular model, in which the catheter is successfully inserted from the ascending aorta, via the aortic arch, into the brachiocephalic trunk. Conclusions The navigation strategy proposed in this paper is feasible and has the advantage of increasing the automation of catheterization, enhancing the manoeuvrability of the active catheter and providing the guiding image with desirable interactivity. Copyright © 2009 John Wiley & Sons, Ltd.

33 citations

Proceedings ArticleDOI
22 May 2011
TL;DR: A novel robotic catheter system with master-slave control, including the steerable catheter integrated with two magnetic tracking sensors, interventional mechanisms with force feedback and 3D guiding image with the collision test is developed.
Abstract: Utilizing catheters with unchangeable distal tip, traditional endovascular minimally invasive surgery is manually performed by surgeons present in an operating room filled with X-ray radiation. It has many disadvantages, such as poor maneuverability, radiation injury and undesirable interactivity, Thus it is difficult to guarantee the safety and efficiency. In order to improve these limitations, this paper develops a novel robotic catheter system with master-slave control, including the steerable catheter integrated with two magnetic tracking sensors, interventional mechanisms with force feedback and 3D guiding image with the collision test. The results demonstrate that the constructed system can reduce the usage of X-rays; surgeons can be located in the control room away from the operating room in the master-slave way; catheterization can be performed successfully and safely to the target point with high maneuverability.

29 citations

Journal ArticleDOI
TL;DR: An active catheter is a minimally invasive surgery catheter that can perform deflectable motions and moves like a snake, utilizing a multi‐joint mechanism with distributed shape memory alloy (SMA) actuators.
Abstract: Background An active catheter is a minimally invasive surgery catheter that can perform deflectable motions. The active catheter can be controlled from outside the body and moves like a snake, utilizing a multi-joint mechanism with distributed shape memory alloy (SMA) actuators. Methods It was considered that the deflection curve of the axis of the catheter is determined by the output force of the SMA actuators. Based on the large deflection theory, the deflection curve equation of the axis of the catheter was derived, using the precise form of the curvature. Results Through experimentation, the axial bending curve shape of the blended active catheter was measured precisely, and the experimental results were compared with the calculation results obtained from the large deflection theory and the circular arc hypothesis. The experimental results show that the curves calculated by large deflection theory are very close to the actual axis curves. Conclusions An active catheter prototype has been designed using the theory presented in this paper. Utilizing a vascular model, the active catheter-based invasive surgery was simulated. The experiment confirmed that the large deflection theory calculation method can be used to guide the design of the active catheter. Copyright © 2008 John Wiley & Sons, Ltd.

24 citations

Patent
27 Apr 2011
TL;DR: In this paper, a catheter robot system for a minimally invasive interventional operation in a blood vessel is described, which aims to lower the radiation hazard to patients and doctors on site.
Abstract: The invention discloses a catheter robot system for a minimally invasive interventional operation in a blood vessel, relating to a robot system for assisting the minimally invasive interventional operation in the blood vessel, which aims to lower the radiation hazard to patients and doctors on site, realize compartmental interventional operation at different sites and feed back the conveying force of a catheter. A main hand handle and a computer mainframe are arranged in a control room; a control cabinet, a catheter handle, master and slave intervention devices, a magnetic field generator and a controllable catheter are arranged in an operation room; a pose signal of the main hand handle is delivered to the control cabinet after processed by the computer mainframe; the control cabinet is internally provided with a motion control card and a driver; the motion control card receives a command to send an instruction to the driver; the driver delivers a control signal to the motors of the master and slave intervention devices, thereby controlling the intervention devices to realize the pushing/pulling, rotation and bending operations of the controllable catheter; a pose sensor acquires pose information on a controllable bent section, and the pose signal is delivered by the motion control card to the computer mainframe for signal processing. The invention is used for the minimally invasive interventional operation in the blood vessel.

14 citations


Cited by
More filters
Journal ArticleDOI
TL;DR: The state of the art in continuum robot manipulators and systems intended for application to interventional medicine are described, and relevant research in design, modeling, control, and sensing for continuum manipulators are discussed.
Abstract: In this paper, we describe the state of the art in continuum robot manipulators and systems intended for application to interventional medicine. Inspired by biological trunks, tentacles, and snakes, continuum robot designs can traverse confined spaces, manipulate objects in complex environments, and conform to curvilinear paths in space. In addition, many designs offer inherent structural compliance and ease of miniaturization. After decades of pioneering research, a host of designs have now been investigated and have demonstrated capabilities beyond the scope of conventional rigid-link robots. Recently, we have seen increasing efforts aimed at leveraging these qualities to improve the frontiers of minimally invasive surgical interventions. Several concepts have now been commercialized, which are inspiring and enabling a current paradigm shift in surgical approaches toward flexible access routes, e.g., through natural orifices such as the nose. In this paper, we provide an overview of the current state of this field from the perspectives of both robotics science and medical applications. We discuss relevant research in design, modeling, control, and sensing for continuum manipulators, and we highlight how this work is being used to build robotic systems for specific surgical procedures. We provide perspective for the future by discussing current limitations, open questions, and challenges.

986 citations

Journal ArticleDOI
28 Aug 2019
TL;DR: A submillimeter-scale, self-lubricating soft continuum robot with omnidirectional steering and navigating capabilities based on magnetic actuation, enabled by programming ferromagnetic domains in its soft body while growing hydrogel skin on its surface is presented.
Abstract: Small-scale soft continuum robots capable of active steering and navigation in a remotely controllable manner hold great promise in diverse areas, particularly in medical applications. Existing continuum robots, however, are often limited to millimeter or centimeter scales due to miniaturization challenges inherent in conventional actuation mechanisms, such as pulling mechanical wires, inflating pneumatic or hydraulic chambers, or embedding rigid magnets for manipulation. In addition, the friction experienced by the continuum robots during navigation poses another challenge for their applications. Here, we present a submillimeter-scale, self-lubricating soft continuum robot with omnidirectional steering and navigating capabilities based on magnetic actuation, which are enabled by programming ferromagnetic domains in its soft body while growing hydrogel skin on its surface. The robot's body, composed of a homogeneous continuum of a soft polymer matrix with uniformly dispersed ferromagnetic microparticles, can be miniaturized below a few hundreds of micrometers in diameter, and the hydrogel skin reduces the friction by more than 10 times. We demonstrate the capability of navigating through complex and constrained environments, such as a tortuous cerebrovascular phantom with multiple aneurysms. We further demonstrate additional functionalities, such as steerable laser delivery through a functional core incorporated in the robot's body. Given their compact, self-contained actuation and intuitive manipulation, our ferromagnetic soft continuum robots may open avenues to minimally invasive robotic surgery for previously inaccessible lesions, thereby addressing challenges and unmet needs in healthcare.

594 citations

Journal ArticleDOI
TL;DR: This survey investigates the recent advances in alternative emerging techniques for 3-D shape sensing in this field and focuses on the following categories: fiber-optic-sensor-based, electromagnetic-tracking- based, and intraoperative imaging modality-based shape-reconstruction methods.
Abstract: Continuum robots provide inherent structural compliance with high dexterity to access the surgical target sites along tortuous anatomical paths under constrained environments and enable to perform complex and delicate operations through small incisions in minimally invasive surgery These advantages enable their broad applications with minimal trauma and make challenging clinical procedures possible with miniaturized instrumentation and high curvilinear access capabilities However, their inherent deformable designs make it difficult to realize 3-D intraoperative real-time shape sensing to accurately model their shape Solutions to this limitation can lead themselves to further develop closely associated techniques of closed-loop control, path planning, human–robot interaction, and surgical manipulation safety concerns in minimally invasive surgery Although extensive model-based research that relies on kinematics and mechanics has been performed, accurate shape sensing of continuum robots remains challenging, particularly in cases of unknown and dynamic payloads This survey investigates the recent advances in alternative emerging techniques for 3-D shape sensing in this field and focuses on the following categories: fiber-optic-sensor-based, electromagnetic-tracking-based, and intraoperative imaging modality-based shape-reconstruction methods The limitations of existing technologies and prospects of new technologies are also discussed

253 citations

Journal ArticleDOI
TL;DR: New technical developments in different aspects of robotic endovascular intervention including catheter instrumentation, intra-operative imaging and navigation techniques, as well as master/slave based robotic catheterization platforms are reviewed and addressed.
Abstract: Endovascular techniques have been embraced as a minimally-invasive treatment approach within different disciplines of interventional radiology and cardiology. The current practice of endovascular procedures, however, is limited by a number of factors including exposure to high doses of X-ray radiation, limited 3D imaging, and lack of contact force sensing from the endovascular tools and the vascular anatomy. More recently, advances in steerable catheters and development of master/slave robots have aimed to improve these practices by removing the operator from the radiation source and increasing the precision and stability of catheter motion with added degrees-of-freedom. Despite their increased application and a growing research interest in this area, many such systems have been designed without considering the natural manipulation skills and ergonomic preferences of the operators. Existing studies on tool interactions and natural manipulation skills of the operators are limited. In this manuscript, new technical developments in different aspects of robotic endovascular intervention including catheter instrumentation, intra-operative imaging and navigation techniques, as well as master/slave based robotic catheterization platforms are reviewed. We further address emerging trends and new research opportunities towards more widespread clinical acceptance of robotically assisted endovascular technologies.

208 citations

Journal ArticleDOI
TL;DR: Remote‐controlled catheter navigation systems have recently been introduced into minimally invasive vascular surgery and some of them have already been applied in clinical practice.
Abstract: Background Remote-controlled catheter navigation systems have recently been introduced into minimally invasive vascular surgery and some of them have already been applied in clinical practice. Steerable catheters with improved manoeuvrability play an important role in these innovations for conventional catheterization. Methods This review details the development of various steerable catheters, both in use clinically and under investigation. Comprehensive comparison and analysis in several key aspects are followed to reveal both the advantages and limitations of these catheters, as well as the requirements for relevant techniques. Results Steerable catheters are able to select direction in the distal end, and superior to conventional counterparts in many aspects. Differences between magnetic and active catheters mainly lie in function, safety, configuration of operating room and cost. They have similar requirements for miniaturization and slave insertion mechanisms. Conclusions Steerable catheters are rapidly evolving and still require technological refinements to extend current capabilities. Copyright © 2009 John Wiley & Sons, Ltd.

140 citations