Zhi-Yong Jiang

Bio: Zhi-Yong Jiang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Aryl & Silylation. The author has an hindex of 3, co-authored 6 publications receiving 88 citations.

A general and efficient protocol for the synthesis of biaryl ethers from aryl silyl ethers using Cs2CO3

Abstract: A general and efficient one-step procedure has been developed for the synthesis of biaryl ethers via direct coupling of electron-deficient arylhalides or aryl triflates to aryl /-butyldimethylsilyl (TBS) ethers using Cs 2 CO 3 . The protocol was also applied to electron-rich arylhalides by addition of a catalytic amount of copper(I) iodide. The reaction is rapid and provides good to excellent yields.

A Mild, Efficient and Selective Deprotection of t‐Butyldimethylsilyl‐Protected Phenols Using Cesium Carbonate.

Abstract: A mild and efficient method for the deprotection of aryl t- butyldimethysilyl (TBS) ethers is described. The protecting group TBS could be cleaved from aryl silyl ethers using cesium carbonate in DMF–H 2 O at room temperature to give the corresponding phenols in excellent yields. The reaction conditions allowed selective deprotection of aryl TBS-protected phenols in the presence of TBS, phenyloxycarbonyl or tetrahydropyranyl-protected alcohols.

Sulfated zirconia as an efficient catalyst for organic synthesis and transformation reactions

Abstract: The efficacy of sulfated zirconia catalyst was investigated towards various acid-catalyzed organic syntheses and transformation reactions in the liquid phase. The SO42−/ZrO2 efficiently catalyzes synthesis of 1,5-benzodiazepine derivatives, electrophilic substitution of indoles with aldehydes to afford the corresponding bis(indolyl)methanes, synthesis of 3,4-dihydropyrimidinones, synthesis of diaryl sulfoxides, and tetrahydropyranylation of alcohols and phenols. Various advantages associated with these protocols include, simple work-up procedure, solvent-free conditions, short reaction times, high product yields and easy recovery and reusability of the catalyst. The SO42−/ZrO2 catalyst was obtained by immersing a finely powdered hydrous Zr(OH)4 into 1 M H2SO4 solution and subsequent drying and calcination at 923 K. The Zr(OH)4 was prepared from aqueous ZrOCl2·8H2O solution by hydrolysis with dilute ammonium hydroxide. The bulk and surface properties of the prepared catalysts were examined by X-ray powder diffraction, BET surface area, ammonia-TPD and Raman spectroscopy techniques. All characterization results revealed that the incorporated sulfate ions show a significant influence on the surface and bulk properties of the ZrO2. In particular, XRD and Raman results suggest that impregnated sulfate ions stabilize the metastable tetragonal phase of ZrO2 at ambient conditions. Ammonia-TPD and BET surface area results indicate that sulfated catalyst exhibits enhanced acid strength and specific surface area than that of unprompted ZrO2.