Zhishan Hua

TL;DR: The performance of magnetic bead-based immunoassays (cardiac troponin I) on a digital microfluidic cartridge in less than 8 minutes using whole blood samples and the capability to perform sample preparation for bacterial infectious disease pathogen, methicillin-resistant Staphylococcus aureus and for human genomic DNA using magnetic beads are demonstrated.

TL;DR: A versatile digital microfluidic platform for multiplexed real-time polymerase chain reactions (PCR) that reliably detected diagnostic DNA levels of methicillin-resistant Staphylococcus aureus, Mycoplasma pneumoniae, and Candida albicans and was consistently repeatable across multiple PCR loops both within and between cartridges.

TL;DR: In this paper, a method of detecting an analyte is provided and includes providing in a detection window a droplet including a signal-producing substance indicative of the presence and/or quantity of analyte and one or more magnetically responsive beads which may interfere with signal produced by the signal producing substance.

TL;DR: A droplet actuator with a droplet formation electrode configuration associated with the droplet operations surface is described in this article, in which the electrode configuration comprises one or more electrodes configured to control volume of a single droplet during the formation of a sub-droplet on the operation surface.

TL;DR: A novel microfluidic real-time PCR platform (Advanced Liquid Logic, Research Triangle Park, NC) that is rapid, portable, and fully automated is evaluated that offers an inexpensive and convenient diagnostic test for microbial DNA.