Author
Zineb Serhier
Bio: Zineb Serhier is an academic researcher from University of Hassan II Casablanca. The author has contributed to research in topics: Population & Cronbach's alpha. The author has an hindex of 12, co-authored 47 publications receiving 360 citations.
Topics: Population, Cronbach's alpha, Health care, Medicine, Health informatics
Papers published on a yearly basis
Papers
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TL;DR: BMI below 22 kg/ m2 is a risk factor for 13-year mortality in older people, but the findings suggest that overweight and obesity may not be associated to mortality after adjustment for established mortality risk factors.
Abstract: Objective: To investigate the relationship between mortality and BMI in older people, taking into account other established mortality risk factors. Methods: A total of 3,646 French community dwellers aged 65 years and older from PAQUID cohort study were included. Cox proportional-hazards analysis was used to assess association between BMI and mortality. Results: Death occurred in 54.1% of the cohort more than 13 years: 68.99% of the underweight (BMI " xbd="1204" xhg="1181" ybd="1711" yhg="1685"/>30), 51.66% of the overweight (BMI 25-30), and 51.79% of the reference participants (BMI 22-25) died.The relative risk of death as a function of BMI, adjusted for gender and age, formed a U-shaped pattern, with larger risks associated with lower BMI (<22.0) and for BMI of 25.0 to 30.0 and BMI ≥30. (BMI 22.0-24.9 was the reference.) After adjustment for demographic factors, smoking history, and comorbidity, increased mortality risk persisted in underweight older people, BMI <18.5 and...
45 citations
TL;DR: The overall prevalence of current smoking in Morocco was 31.5% for males and 3.1% for females, and smoking was associated with lower educational level and social class, and a comprehensive strategy for tobacco control is needed.
Abstract: To study the prevalence and determinants of cigarette smoking in Morocco. A sample of 9,195 individuals aged 15–90 years, were randomly selected, using a stratified cluster sampling technique. A cross-sectional, household, community-based survey was conducted using a tested questionnaire. The interview covered personal, social and educational characteristics of the respondents and their smoking status. The association between current smoking and sociodemographic variables was estimated. The overall prevalence of current smoking was 31.5% for males and 3.1% for females. In men, smoking was associated with lower educational level. In women, it was associated with higher educational level and social class. Cigarette smoking remains an important public health problem in Morocco. A comprehensive strategy for tobacco control is needed.
38 citations
TL;DR: Although there was no evidence of an association between the ENPP1 K121Q variant and the general phenotype of T2D, it was found that the Q121 variant was significantly more frequent in obese than in non-obese subjects after adjusting for age, gender and T1D status.
27 citations
Journal Article•
TL;DR: The results of the MARTA survey indicate a need for tobacco control to reach all sectors of society, and especially the illiterate population in Morocco.
Abstract: CADRE : Le lien entre tabagisme et bas niveau socio-economique indique par des bas niveaux d'etudes n'est plus a demontrer. Au Maroc, cette association n'a jamais ete examinee. OBJECTIF : L'enquete MARTA a ete realisee dans la population marocaine pour etudier la prevalence du tabagisme en fonction du niveau d'education et d'autres caracteristiques sociodemographiques. METHODES Il s'agit d'une etude transversale qui a ete conduite en 2005-2006 sur un echantillon representatif de la population marocaine. Les donnees recueillies a travers un questionnaire etaient : les informations sociodemographiques, le niveau d'etudes et le statut tabagique. Des comparaisons ont ete faites pour determiner si le statut tabagique differait significativement entre les differents niveaux d'etudes et par rapport aux variables demographiques. Une regression logistique multiple a ete utilisee pour calculer des OR ajustes selon le niveau d'etude. RESULTATS : Un total de 9195 sujets ont ete inclus dans l'etude ; 52% etaient des hommes et 17,9% etaient analphabetes. La prevalence globale des fumeurs actuels a ete de 18,0% (IC95% 17,2-18,8) : 31,5% (IC95% 30,2-32,9) chez les hommes et 3,3% (IC95% 2,8-3,8) chez les femmes. La prevalence de fumeurs actuels etait inversement associee au niveau d'education chez les hommes et augmente avec le niveau d'etude chez les femmes. Le risque d'etre fumeurs actuels est plus eleve chez les hommes analphabetes que chez ceux dont le niveau d'etude est universitaire (OR 1,93 ; IC95% 1,51-2,46). CONCLUSION : Ces resultats soulignent la necessite d'un meilleur controle du tabagisme ciblant particulierement la population analphabete.
24 citations
Journal Article•
TL;DR: A Moroccan Arabic version of the St George's Respiratory Questionnaire (SGRQ) in patients with COPD or asthma in Morocco yielded satisfactory psychometric properties.
Abstract: CADRE: Les broncho-pneumopathies chroniques obstructives (BPCO) et l'asthme constituent un veritable probleme de sante publique au Maroc. Leur evaluation doit etre completee par une mesure de la qualite de vie. Cependant, aucun instrument specifique n'est disponible en langue arabe locale marocaine. OBJECTIF : Evaluer la validite et la fiabilite d'une version arabe marocaine du St George's Respiratory Questionnaire (SGRQ) chez des patients atteints de BPCO ou d'asthme au Maroc. METHODES: Apres un processus rigoureux de traduction contre-traduction du SGRQ en arabe dialectal marocain (SGRQm), le SGRQm, la spirometrie, l'echelle de Fletcher et l'echelle visuelle analogique (EVA) ont ete administres a chaque patient lors du recrutement. Les donnees recueillies ont permis d'evaluer la fiabilite interne et la validite de la structure du SGRQm. Pour evaluer la fiabilite test-retest, chaque patient a complete a nouveau le SGRQm 10 jours plus tard. RESULTATS: Au total 131 patients ont ete recrutes dans cette etude. L'âge moyen etait de 52 ans. Les patients avaient un VEMS moyen de 1,70 1 et une EVA moyenne de 51,5 mm. La coherence interne des differentes composantes (symptomes, activites et impact), evaluee a l'aide du coefficient de fiabilite a de Cronbach, ont ete respectivement de 0,94 ; 0,91 et 0,90. La fiabilite test-retest a varie de 0,70 a 0,87. L'echelle de Fletcher a ete en correlation avec tous les scores du SGRQm, tandis que la correlation de l'EVA a ete similaire sauf pour la dimension symptomes (P > 0.05). Le VEMS est en correlation negative et statistiquement significative avec toutes les dimensions du SGRQm. CONCLUSION: Les proprietes psychometriques du SGRQm sont satisfaisantes.
20 citations
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TL;DR: The epidemiology of endemic health-care-associated infection in developing countries is assessed and a need to improve surveillance and infection-control practices is indicated.
1,737 citations
TL;DR: There was a U shaped association between BMI and mortality in analyses with a greater potential for bias including all participants, current, former, or ever smokers, and in studies with a short duration of follow-up (<5 years or <10 years), or with moderate study quality scores.
Abstract: Objective To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding from smoking, weight loss associated with disease, and preclinical disease. Data sources PubMed and Embase databases searched up to 23 September 2015. Study selection Cohort studies that reported adjusted risk estimates for at least three categories of BMI in relation to all cause mortality. Data synthesis Summary relative risks were calculated with random effects models. Non-linear associations were explored with fractional polynomial models. Results 230 cohort studies (207 publications) were included. The analysis of never smokers included 53 cohort studies (44 risk estimates) with >738 144 deaths and >9 976 077 participants. The analysis of all participants included 228 cohort studies (198 risk estimates) with >3 744 722 deaths among 30 233 329 participants. The summary relative risk for a 5 unit increment in BMI was 1.18 (95% confidence interval 1.15 to 1.21; I 2 =95%, n=44) among never smokers, 1.21 (1.18 to 1.25; I 2 =93%, n=25) among healthy never smokers, 1.27 (1.21 to 1.33; I 2 =89%, n=11) among healthy never smokers with exclusion of early follow-up, and 1.05 (1.04 to 1.07; I 2 =97%, n=198) among all participants. There was a J shaped dose-response relation in never smokers (P non-linearity Conclusion Overweight and obesity is associated with increased risk of all cause mortality and the nadir of the curve was observed at BMI 23-24 among never smokers, 22-23 among healthy never smokers, and 20-22 with longer durations of follow-up. The increased risk of mortality observed in underweight people could at least partly be caused by residual confounding from prediagnostic disease. Lack of exclusion of ever smokers, people with prevalent and preclinical disease, and early follow-up could bias the results towards a more U shaped association.
583 citations
TL;DR: For older populations, being overweight was not found to be associated with an increased risk of mortality; however, there was a increased risk for those at the lower end of the recommended BMI range for adults.
495 citations
01 Jan 2014
TL;DR: In this article, a 2-stage random-effects meta-analysis was performed of studies published from 1990 to 2013 that reported the RRs of all-cause mortality for community-based adults aged ≥ 65 y.
Abstract: Background: Whether the association between body mass index (BMI) and all-cause mortality for older adults is the same as for younger adults is unclear. Objective: The objective was to determine the association between BMI and all-cause mortality risk in adults $65 y of age. Design: A 2-stage random-effects meta-analysis was performed of studies published from 1990 to 2013 that reported the RRs of allcause mortality for community-based adults aged $65 y. Results: Thirty-two studies met the inclusion criteria; these studies included 197,940 individuals with an average follow-up of 12 y. With the use of a BMI (in kg/m 2 ) of 23.0–23.9 as the reference, there was a 12% greater risk of mortality for a BMI range of 21.0– 21.9 and a 19% greater risk for a range of 20.0–20.9 [BMI of 21.0– 21.9; HR (95% CI): 1.12 (1.10, 1.13); BMI of 20.0–20.9; HR (95% CI): 1.19 (1.17, 1.22)]. Mortality risk began to increase for BMI .33.0 [BMI of 33.0–33.9; HR (95% CI): 1.08 (1.00, 1.15)]. Selfreported anthropometric measurements, adjustment for intermediary factors, and exclusion of early deaths or preexisting disease did not markedly alter the associations, although there was a slight attenuation of the association in never-smokers. Conclusions: For older populations, being overweight was not found to be associated with an increased risk of mortality; however, there was an increased risk for those at the lower end of the recommended BMI range for adults. Because the risk of mortality increased in older people with a BMI ,23.0, it would seem appropriate to monitor weight status in this group to address any modifiable causes of weight loss promptly with due consideration of individual comorbidities. Am J Clin Nutr doi: 10.3945/ajcn.113.068122.
421 citations