In the present paper a research has been done on the essay ‘Can the Subaltern Speak’ by’ Gayatri Chakravorty Spivak’. It has been explained into much simpler language about what the author conveys for better understanding and further references. Also the criticism has been done by various critiques from various sources which is helpful from examination point of view. The paper has been divided into various contexts with an introduction and the conclusions. Also the references has been written that depicts the sources of criticism.

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Can the Subaltern Speak

To raise the question of the nature of narrative is to invite reflection on the very nature of culture and, possibly, even on the nature of humanity itself. So natural is the impulse to narrate, so inevitable is the form of narrative for any report of the way things really happened, that narrativity could appear problematical only in a culture in which it was absent-absent or, as in some domains of contemporary Western intellectual and artistic culture, programmatically refused. As a panglobal fact of culture, narrative and narration are less problems than simply data. As the late (and already profoundly missed) Roland Barthes remarked, narrative "is simply there like life itself. . international, transhistorical, transcultural."' Far from being a problem, then, narrative might well be considered a solution to a problem of general human concern, namely, the problem of how to translate knowing into telling,2 the problem of fashioning human experience into a form assimilable to structures of meaning that are generally human rather than culture-specific. We may not be able fully to comprehend specific thought patterns of another culture, but we have relatively less difficulty understanding a story coming from another culture, however exotic that

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The Value of Narrativity in the Representation of Reality

Time is divided by geologists according to marked shifts in Earth's state. Recent global environmental changes suggest that Earth may have entered a new human-dominated geological epoch, the Anthropocene. Here we review the historical genesis of the idea and assess anthropogenic signatures in the geological record against the formal requirements for the recognition of a new epoch. The evidence suggests that of the various proposed dates two do appear to conform to the criteria to mark the beginning of the Anthropocene: 1610 and 1964. The formal establishment of an Anthropocene Epoch would mark a fundamental change in the relationship between humans and the Earth system.

Defining the Anthropocene

The politics of life itself Biomedicine, power, and subjectivity in the twenty-first century

The dramatic advances in DNA technology over the last few years are the stuff of science fiction. It is now not only possible to clone human beings it is happening. For the first time since the creation of the earth four billion years ago, or the emergence of mankind 10 million years ago, people will be able to choose their children's' sex, height, colour, personality traits and intelligence. It will even be possible to create 'superhumans' by mixing human genes with those of other animals for extra strength or longevity. But is this desirable? What are the moral and political consequences? Will it mean anything to talk about 'human nature' any more? Is this the end of human beings? Post Human Society is a passionate analysis of the greatest political and moral problem ever to face the human race.

The Problem with NatureOur Posthuman Future: Consequences of the Biotechnology Revolution

Most drugs exert their effects via multitarget interactions, as hypothesized by polypharmacology. While these multitarget interactions are responsible for the clinical effect profiles of drugs, current methods have failed to uncover the complex relationships between them. Here, we introduce an approach which is able to relate complex drug-protein interaction profiles with effect profiles. Structural data and registered effect profiles of all small-molecule drugs were collected, and interactions to a series of nontarget protein binding sites of each drug were calculated. Statistical analyses confirmed a close relationship between the studied 177 major effect categories and interaction profiles of ca. 1200 FDA-approved small-molecule drugs. On the basis of this relationship, the effect profiles of drugs were revealed in their entirety, and hitherto uncovered effects could be predicted in a systematic manner. Our results show that the prediction power is independent of the composition of the protein set used for interaction profile generation.

Drug effect prediction by polypharmacology-based interaction profiling.

Our understanding of ourselves and the world as historical has drastically changed since the postwar period, yet this emerging historical sensibility has not been appropriately explained in a coherent theory of history. In this book, Zoltán Simon argues that instead of seeing the past, the present and the future together on a temporal continuum as history, we now expect unprecedented change to happen in the future (in visions of the future of technology, ecology and nuclear warfare) and we look at the past by assuming that such changes have already happened.
This radical theory of history challenges narrative conceptualizations of history which assume a past potential of humanity unfolding over time to reach future fulfillment and seeks new ways of conceptualizing the altered socio-cultural concerns Western societies are currently facing. By creating a novel set of concepts to make sense of our altered historical condition regarding both history understood as the course of human affairs and historical writing, History in Times of Unprecedented Change offers a highly original and engaging take on the state of history and historical theory in the present and beyond.

History in Times of Unprecedented Change: A Theory for the 21st Century

An essential element usually passes unnoticed in recent discussion about how history as an academic discipline is supposed to be relevant for the shaping of our public life. It is the concept of history itself (history as both the course of events and historical writing) that underlies the whole discussion, which also configures the two currently most influential and fashionable efforts to reinstate the public relevance of history: The History Manifesto, co-authored by Jo Guldi and David Armitage, and Hayden White's The Practical Past. In advising to turn to the past in order to shape the present and the future, both books rely on the familiar developmental view that characterised nineteenth-century thinking in general, and on which the discipline of history became institutionalised in particular. The author's main contention in this essay is that turning to this notion of history is not the solution for the problem of the supposed public irrelevance of professional historical studies, but the problem its...

History Manifested: Making Sense of Unprecedented Change

This paper argues that the tendency to invoke modern historical thinking in trying to make sense of the Anthropocene amounts to an untenable, self-contradictory, and self-defeating enterprise. There is a fundamental contradiction between the prospect of unprecedented change as entailed by the Anthropocene and the deep continuity of a processual historical change. On the one hand, conceiving the Anthropocene as the prospect of the unprecedented creates a demand for immediate action to prevent future catastrophe. On the other hand, pointing out the inequalities in the historical process of bringing about the Anthropocene creates a demand for social justice. Although both are legitimate and important demands, they are incompatible. They represent different temporalities, different conceptions of change, and different modes of action. Inasmuch as the Anthropocene appears as unprecedented, it does not have a processual history; and inasmuch as it has a processual history, it is not the Anthropocene.

https://scholarlypublications.universiteitleiden.nl/access/item%3A2981276/view

Why the Anthropocene has no history: Facing the unprecedented:

The rapidly growing transdisciplinary enthusiasm about developing new kinds of Anthropocene stories is based on the shared assumption that the Anthropocene predicament is best made sense of by narrative means Against this assumption, this article argues that the challenge we are facing today does not merely lie in telling either scientific, socio-political, or entangled Anthropocene narratives to come to terms with our current condition Instead, the challenge lies in coming to grips with how the stories we can tell in the Anthropocene relate to the radical novelty of the Anthropocene condition about which no stories can be told What we need to find are meaningful ways to reconcile an inherited commitment to narrativization and the collapse of storytelling as a vehicle of understanding the Anthropocene as our current predicament

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Zoltán Boldizsár Simon

Papers

Drug effect prediction by polypharmacology-based interaction profiling.

History in Times of Unprecedented Change: A Theory for the 21st Century

History Manifested: Making Sense of Unprecedented Change

Why the Anthropocene has no history: Facing the unprecedented:

The limits of Anthropocene narratives