Biomedical Engineering 

About: Biomedical Engineering is an academic conference. The conference publishes majorly in the area(s): Computer science & Medicine. Over the lifetime, 3360 publications have been published by the conference receiving 10472 citations.

Transport of molecules, particles, and cells in solid tumors.

Abstract: Extraordinary advances in molecular biology and biotechnology have led to the development of a vast number of therapeutic anti-cancer agents. To reach cancer cells in a tumor, a blood-borne therapeutic molecule, particle, or cell must make its way into the blood vessels of the tumor and across the vessel wall into the interstitium, which it then must migrate through. Unfortunately, tumors often develop in ways that hinder these steps. The goal of research in this area is to analyze each of these steps experimentally and theoretically and integrate the resulting information into a unified theoretical framework. This paradigm of analysis and synthesis has fostered a better understanding of physiological barriers in solid tumors and aided in the development of novel strategies to exploit and/or overcome these barriers for improved cancer detection and treatment.

A bioengineering analysis of force actions at the knee in normal and pathological gait.

Abstract: The paper describes a simplified bioengineering analysis for the determination of force actions at the knee joint for normal and pathological gaits. The stance phase of the gait cycle only is considered, and gravitational and inertia forces are excluded from the analysis. The anatomical and functional assumptions required for analysis are discussed. Force actions transmitted at the knee joint by the bearing surfaces, muscles and ligaments for normal individuals are presented with reference to magnitude and phasic relationship for the activity of level walking. Bearing loads transmitted at the knee joints of pathological limbs are also discussed.

Porous surface layered prosthetic devices.

Abstract: The method of fabrication and properties of a dual structured implant system consisting of a metallic porous surface layer is described. The ingrowth of bone tissue into the outer porous surface layer results in part fixation, while the solid inner core region provides the necessary mechanical strength for a device used for the replacement of heavy load bearing joint regions such as the hip and knee. Additionally, novel implant systems are suggested using the porous coating concept.