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open access Open Access ISSN: 16177959 e-ISSN: 16177940

Biomechanics and Modeling in Mechanobiology — Template for authors

Publisher: Springer
Categories Rank Trend in last 3 yrs
Modeling and Simulation #52 of 290 down down by 38 ranks
Mechanical Engineering #128 of 596 down down by 82 ranks
Biotechnology #94 of 282 down down by 42 ranks
journal-quality-icon Journal quality:
High
calendar-icon Last 4 years overview: 551 Published Papers | 2633 Citations
indexed-in-icon Indexed in: Scopus
last-updated-icon Last updated: 05/06/2020
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FAQ

Journal Performance & Insights

  • Impact Factor
  • CiteRatio
  • SJR
  • SNIP

Impact factor determines the importance of a journal by taking a measure of frequency with which the average article in a journal has been cited in a particular year.

2.527

11% from 2018

Impact factor for Biomechanics and Modeling in Mechanobiology from 2016 - 2019
Year Value
2019 2.527
2018 2.829
2017 3.212
2016 3.323
graph view Graph view
table view Table view

insights Insights

  • Impact factor of this journal has decreased by 11% in last year.
  • This journal’s impact factor is in the top 10 percentile category.

CiteRatio is a measure of average citations received per peer-reviewed paper published in the journal.

4.8

8% from 2019

CiteRatio for Biomechanics and Modeling in Mechanobiology from 2016 - 2020
Year Value
2020 4.8
2019 5.2
2018 5.2
2017 5.4
2016 5.5
graph view Graph view
table view Table view

insights Insights

  • CiteRatio of this journal has decreased by 8% in last years.
  • This journal’s CiteRatio is in the top 10 percentile category.

SCImago Journal Rank (SJR) measures weighted citations received by the journal. Citation weighting depends on the categories and prestige of the citing journal.

0.765

10% from 2019

SJR for Biomechanics and Modeling in Mechanobiology from 2016 - 2020
Year Value
2020 0.765
2019 0.85
2018 1.001
2017 1.138
2016 1.102
graph view Graph view
table view Table view

insights Insights

  • SJR of this journal has decreased by 10% in last years.
  • This journal’s SJR is in the top 10 percentile category.

Source Normalized Impact per Paper (SNIP) measures actual citations received relative to citations expected for the journal's category.

1.225

6% from 2019

SNIP for Biomechanics and Modeling in Mechanobiology from 2016 - 2020
Year Value
2020 1.225
2019 1.159
2018 1.262
2017 1.323
2016 1.221
graph view Graph view
table view Table view

insights Insights

  • SNIP of this journal has increased by 6% in last years.
  • This journal’s SNIP is in the top 10 percentile category.

Related Journals

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CiteRatio: 6.0 | SJR: 1.229 | SNIP: 1.764
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CiteRatio: 8.6 | SJR: 1.669 | SNIP: 2.292
open access Open Access ISSN: 13697072 e-ISSN: 14602687

Springer

CiteRatio: 2.4 | SJR: 0.432 | SNIP: 0.771
Biomechanics and Modeling in Mechanobiology

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Springer

Biomechanics and Modeling in Mechanobiology

Mechanics regulates biological processes at the molecular, cellular, tissue, organ, and organism levels. The goal of this journal is to promote basic and applied research that integrates the expanding knowledge-bases in the allied fields of biomechanics and mechanobiology. App...... Read More

Modelling and Simulation

Mechanical Engineering

Biotechnology

Mathematics

i
Last updated on
05 Jun 2020
i
ISSN
1617-7959
i
Impact Factor
High - 1.295
i
Open Access
No
i
Sherpa RoMEO Archiving Policy
Green faq
i
Plagiarism Check
Available via Turnitin
i
Endnote Style
Download Available
i
Bibliography Name
SPBASIC
i
Citation Type
Author Year
(Blonder et al, 1982)
i
Bibliography Example
Beenakker CWJ (2006) Specular andreev reflection in graphene. Phys Rev Lett 97(6):067,007, URL 10.1103/PhysRevLett.97.067007

Top papers written in this journal

open accessOpen access Journal Article DOI: 10.1007/S10237-011-0325-Z
Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy.

Abstract:

Mechanical properties of the adventitia are largely determined by the organization of collagen fibers. Measurements on the waviness and orientation of collagen, particularly at the zero-stress state, are necessary to relate the structural organization of collagen to the mechanical response of the adventitia. Using the fluores... Mechanical properties of the adventitia are largely determined by the organization of collagen fibers. Measurements on the waviness and orientation of collagen, particularly at the zero-stress state, are necessary to relate the structural organization of collagen to the mechanical response of the adventitia. Using the fluorescence collagen marker CNA38-OG488 and confocal laser scanning microscopy, we imaged collagen fibers in the adventitia of rabbit common carotid arteries ex vivo. The arteries were cut open along their longitudinal axes to get the zero-stress state. We used semi-manual and automatic techniques to measure parameters related to the waviness and orientation of fibers. Our results showed that the straightness parameter (defined as the ratio between the distances of endpoints of a fiber to its length) was distributed with a beta distribution (mean value 0.72, variance 0.028) and did not depend on the mean angle orientation of fibers. Local angular density distributions revealed four axially symmetric families of fibers with mean directions of 0°, 90°, 43° and −43°, with respect to the axial direction of the artery, and corresponding circular standard deviations of 40°, 47°, 37° and 37°. The distribution of local orientations was shifted to the circumferential direction when measured in arteries at the zero-load state (intact), as compared to arteries at the zero-stress state (cut-open). Information on collagen fiber waviness and orientation, such as obtained in this study, could be used to develop structural models of the adventitia, providing better means for analyzing and understanding the mechanical properties of vascular wall. read more read less

Topics:

Waviness (51%)51% related to the paper, Adventitia (50%)50% related to the paper
View PDF
689 Citations
Journal Article DOI: 10.1007/S10237-005-0012-Z
An introductory review of cell mechanobiology.
James H.-C. Wang1, B P. Thampatty1

Abstract:

Mechanical loads induce changes in the structure, composition, and function of living tissues. Cells in tissues are responsible for these changes, which cause physiological or pathological alterations in the extracellular matrix (ECM). This article provides an introductory review of the mechanobiology of load-sensitive cells ... Mechanical loads induce changes in the structure, composition, and function of living tissues. Cells in tissues are responsible for these changes, which cause physiological or pathological alterations in the extracellular matrix (ECM). This article provides an introductory review of the mechanobiology of load-sensitive cells in vivo, which include fibroblasts, chondrocytes, osteoblasts, endothelial cells, and smooth muscle cells. Many studies have shown that mechanical loads affect diverse cellular functions, such as cell proliferation, ECM gene and protein expression, and the production of soluble factors. Major cellular components involved in the mechanotransduction mechanisms include the cytoskeleton, integrins, G proteins, receptor tyrosine kinases, mitogen-activated protein kinases, and stretch-activated ion channels. Future research in the area of cell mechanobiology will require novel experimental and theoretical methodologies to determine the type and magnitude of the forces experienced at the cellular and sub-cellular levels and to identify the force sensors/receptors that initiate the cascade of cellular and molecular events read more read less

Topics:

Mechanobiology (66%)66% related to the paper, Mechanotransduction (58%)58% related to the paper, Extracellular matrix (54%)54% related to the paper, Integrin (53%)53% related to the paper, Receptor tyrosine kinase (53%)53% related to the paper
496 Citations
Journal Article DOI: 10.1007/S10237-004-0053-8
Single lamellar mechanics of the human lumbar anulus fibrosus
Gerhard Holzapfel1, Christian Schulze-Bauer1, Guenter Feigl2, Peter Regitnig2

Abstract:

The mechanical behavior of the entire anulus fibrosus is determined essentially by the tensile properties of its lamellae, their fiber orientations, and the regional variation of these quantities. Corresponding data are rare in the literature. The paper deals with an in vitro study of single lamellar anulus lamellae and aims ... The mechanical behavior of the entire anulus fibrosus is determined essentially by the tensile properties of its lamellae, their fiber orientations, and the regional variation of these quantities. Corresponding data are rare in the literature. The paper deals with an in vitro study of single lamellar anulus lamellae and aims to determine (i) their tensile response and regional variation, and (ii) the orientation of lamellar collagen fibers and their regional variation. Fresh human body-disc-body units (L1–L2, n=11) from cadavers were cut midsagittally producing two hemidisc units. One hemidisc was used for the preparation of single lamellar anulus specimens for tensile testing, while the other one was used for the investigation of the lamellar fiber orientation. Single lamellar anulus specimens with adjacent bone fragments were isolated from four anatomical regions: superficial and deep lamellae (3.9±0.21 mm, mean ± SD, apart from the outer boundary surface of the anulus fibrosus) at ventro-lateral and dorsal positions. The specimens underwent cyclic uniaxial tensile tests at three different strain rates in 0.15 mol/l NaCl solution at 37°C, whereby the lamellar fiber direction was aligned with the load axis. For the characterization of the tensile behavior three moduli were calculated: Elow (0–0.1 MPa), Emedium (0.1–0.5 MPa) and Ehigh (0.5–1 MPa). Additionally, specimens were tested with the load axis transverse to the fiber direction. From the second hemidisc fiber angles with respect to the horizontal plane were determined photogrammetrically from images taken at six circumferential positions from ventral to dorsal and at three depth levels. Tensile moduli along the fiber direction were in the range of 28–78 MPa (regional mean values). Superficial lamellae have larger Emedium (p=0.017) and Ehigh (p=0.012) than internal lamellae, and the mean value of superficial lamellae is about three times higher than that of deep lamellae. Tensile moduli of ventro-lateral lamellae do not differ significantly from the tensile moduli of dorsal lamellae, and Elow is generally indifferent with respect to the anatomical region. Tensile moduli transverse to the fiber direction were about two orders of magnitude smaller (0.22±0.2 MPa, mean ± SD, n=5). Tensile properties are not correlated significantly with donor age. Only small viscoelastic effects were observed. The regional variation of lamellar fiber angle ϕ is described appropriately by a regression line |ϕ|=23.2+0.130×α (r2=0.55, p<0.001), where α is the polar angle associated with the circumferential position. The single anulus lamella may be seen as the elementary structural unit of the anulus fibrosus, and exhibits marked anisotropy and distinct regional variation of tensile properties and fiber angles. These features must be considered for appropriate physical and numerical modeling of the anulus fibrosus. read more read less

Topics:

Lamellar structure (53%)53% related to the paper, Tensile testing (51%)51% related to the paper
344 Citations
Journal Article DOI: 10.1007/S10237-006-0068-4
Cell traction force and measurement methods.
James H.-C. Wang, Jeen-Shang Lin1

Abstract:

Cell traction forces (CTFs) are crucial to many biological processes such as inflammation, wound healing, angiogenesis, and metastasis. CTFs are generated by actomyosin interactions and actin polymerization and regulated by intracellular proteins such as alpha-smooth muscle actin (alpha-SMA) and soluble factors such as transf... Cell traction forces (CTFs) are crucial to many biological processes such as inflammation, wound healing, angiogenesis, and metastasis. CTFs are generated by actomyosin interactions and actin polymerization and regulated by intracellular proteins such as alpha-smooth muscle actin (alpha-SMA) and soluble factors such as transforming growth factor-beta (TGF-beta). Once transmitted to the extracellular matrix (ECM) through stress fibers via focal adhesions, which are assemblies of ECM proteins, transmembrane receptors, and cytoplasmic structural and signaling proteins (e.g., integrins), CTFs direct many cellular functions, including cell migration, ECM organization, and mechanical signal generation. Various methods have been developed over the years to measure CTFs of both populations of cells and of single cells. At present, cell traction force microscopy (CTFM) is among the most efficient and reliable method for determining CTF field of an entire cell spreading on a two-dimensional (2D) substrate surface. There are currently three CTFM methods, each of which is unique in both how displacement field is extracted from images and how CTFs are subsequently estimated. A detailed review and comparison of these methods are presented. Future research should improve CTFM methods such that they can automatically track dynamic CTFs, thereby providing new insights into cell motility in response to altered biological conditions. In addition, research effort should be devoted to developing novel experimental and theoretical methods for determining CTFs in three-dimensional (3D) matrix, which better reflects physiological conditions than 2D substrate used in current CTFM methods. read more read less

Topics:

Focal adhesion (51%)51% related to the paper
252 Citations
open accessOpen access Journal Article DOI: 10.1007/S10237-008-0139-9
Spherical indentation of soft matter beyond the Hertzian regime: numerical and experimental validation of hyperelastic models
David C. Lin1, David I. Shreiber2, Emilios K. Dimitriadis1, Ferenc Horkay1

Abstract:

The lack of practicable nonlinear elastic contact models frequently compels the inappropriate use of Hertzian models in analyzing indentation data and likely contributes to inconsistencies associated with the results of biological atomic force microscopy measurements. We derived and validated with the aid of the finite elemen... The lack of practicable nonlinear elastic contact models frequently compels the inappropriate use of Hertzian models in analyzing indentation data and likely contributes to inconsistencies associated with the results of biological atomic force microscopy measurements. We derived and validated with the aid of the finite element method force-indentation relations based on a number of hyperelastic strain energy functions. The models were applied to existing data from indentation, using microspheres as indenters, of synthetic rubber-like gels, native mouse cartilage tissue, and engineered cartilage. For the biological tissues, the Fung and single-term Ogden models achieved the best fits of the data while all tested hyperelastic models produced good fits for the synthetic gels. The Hertz model proved to be acceptable for the synthetic gels at small deformations (strain < 0.05 for the samples tested), but not for the biological tissues. Although this finding supports the generally accepted view that many soft materials can be assumed to be linear elastic at small deformations, the nonlinear models facilitate analysis of intrinsically nonlinear tissues and large-strain indentation behavior. read more read less

Topics:

Hyperelastic material (56%)56% related to the paper, Ogden (54%)54% related to the paper, Indentation (53%)53% related to the paper, Linear elasticity (50%)50% related to the paper
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236 Citations
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SHERPA/RoMEO Database

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RoMEO Colour Archiving policy
Green Can archive pre-print and post-print or publisher's version/PDF
Blue Can archive post-print (ie final draft post-refereeing) or publisher's version/PDF
Yellow Can archive pre-print (ie pre-refereeing)
White Archiving not formally supported
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  2. Post-prints as being the version of the paper after peer-review, with revisions having been made.

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