Institution
Aalto University
Education•Espoo, Finland•
About: Aalto University is a education organization based out in Espoo, Finland. It is known for research contribution in the topics: Population & Carbon nanotube. The organization has 9969 authors who have published 32648 publications receiving 829626 citations. The organization is also known as: TKK & Aalto-korkeakoulu.
Topics: Population, Carbon nanotube, Cellulose, Graphene, Thin film
Papers published on a yearly basis
Papers
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European Commission1, National University of Singapore2, International Institute for Applied Systems Analysis3, University of Nebraska–Lincoln4, Flinders University5, International Water Management Institute6, UNESCO-IHE Institute for Water Education7, Aalto University8, Stockholm Resilience Centre9, South University of Science and Technology of China10
TL;DR: It is recommended that WS is measured based on net abstraction as well, in addition to currently only measuring WS based on gross abstraction, because it does incorporate EFR and Temporal and spatial disaggregation is indeed defined as a goal in more advanced monitoring levels.
209 citations
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TL;DR: Androgen-regulated miR-32 is overexpressed in CRPC, leading to reduced expression of BTG2, a potential marker for aggressive disease and is a putative drug target in PC.
Abstract: The androgen receptor (AR) signaling pathway is involved in the emergence of castration-resistant prostate cancer (CRPC). Here, we identified several androgen-regulated microRNAs (miRNAs) that may contribute to the development of CRPC. Seven miRNAs, miR-21, miR-32, miR-99a, miR-99b, miR-148a, miR-221 and miR-590-5p, were found to be differentially expressed in CRPC compared with benign prostate hyperplasia (BPH) according to microarray analyses. Significant growth advantage for LNCaP cells transfected with pre-miR-32 and pre-miR-148a was found. miR-32 was demonstrated to reduce apoptosis, whereas miR-148a enhanced proliferation. Androgen regulation of miR-32 and miR-148a was confirmed by androgen stimulation of the LNCaP cells followed by expression analyses. The AR-binding sites in proximity of these miRNAs were demonstrated with chromatin immunoprecipitation (ChIP). To identify target genes for the miRNAs, mRNA microarray analyses were performed with LNCaP cells transfected with pre-miR-32 and pre-miR-148a. Expression of BTG2 and PIK3IP1 was reduced in the cells transfected with pre-miR-32 and pre-miR-148a, respectively. Also, the protein expression was reduced according to western blot analysis. BTG2 and PIK3IP1 were confirmed to be targets by 3′UTR-luciferase assays. Finally, immunostainings showed a statistically significant (P<0.0001) reduction of BTG2 protein in CRPCs compared with untreated prostate cancer (PC). The lack of BTG2 staining was also associated (P<0.01) with a short progression-free time in patients who underwent prostatectomy. In conclusion, androgen-regulated miR-32 is overexpressed in CRPC, leading to reduced expression of BTG2. Thus, miR-32 is a potential marker for aggressive disease and is a putative drug target in PC.
209 citations
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TL;DR: In this article, the authors proposed a method based on general relations between the reflection and transmission coefficients and the polarizabilities of arbitrary bi-anisotropic particles to synthesize different polarization-transforming devices realized as arrays of small particles.
Abstract: We study the possibility of analytically synthesizing different polarization-transforming devices realized as arrays of small particles. The proposed method is based on general relations between the reflection and transmission coefficients and the polarizabilities of arbitrary bi-anisotropic particles. As an example, we reveal all possible types of inclusions which can be used to realize twist polarizers, select one of them and synthesize a novel twist polarizer. The synthesized twist polarizer is then fitted on a standard printed circuit board, optimized numerically, and finally manufactured and measured. The experimental results for the twist polarizer show good correspondence with the simulations and the new method is found to be a useful tool for developing any polarization-transforming devices. As one more example, a novel circular polarization selective surface is synthesized.
209 citations
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TL;DR: During the 140 h experiment, the solar cells with the Au electrode experience a dramatic, irreversible efficiency loss, rendering them effectively nonoperational, whereas the SWCNT-contacted devices show only a small linear efficiency loss with an extrapolated lifetime of 580 h.
Abstract: Mixed ion perovskite solar cells (PSC) are manufactured with a metal-free hole contact based on press-transferred single-walled carbon nanotube (SWCNT) film infiltrated with 2,2,7,-7-tetrakis(N,N-di-p-methoxyphenylamine)-9,90-spirobifluorene (Spiro-OMeTAD). By means of maximum power point tracking, their stabilities are compared with those of standard PSCs employing spin-coated Spiro-OMeTAD and a thermally evaporated Au back contact, under full 1 sun illumination, at 60 °C, and in a N2 atmosphere. During the 140 h experiment, the solar cells with the Au electrode experience a dramatic, irreversible efficiency loss, rendering them effectively nonoperational, whereas the SWCNT-contacted devices show only a small linear efficiency loss with an extrapolated lifetime of 580 h.
208 citations
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TL;DR: The accidental discovery of a 2D silica glass supported on graphene enables the first atomic resolution transmission electron microscopy of a glass, producing images that strikingly resemble Zachariasen's original 1932 cartoon models of 2D continuous random network glasses.
Abstract: Large-area graphene substrates provide a promising lab bench for synthesizing, manipulating, and characterizing low-dimensional materials, opening the door to high-resolution analyses of novel structures, such as two-dimensional (2D) glasses, that cannot be exfoliated and may not occur naturally. Here, we report the accidental discovery of a 2D silica glass supported on graphene. The 2D nature of this material enables the first atomic resolution transmission electron microscopy of a glass, producing images that strikingly resemble Zachariasen's original 1932 cartoon models of 2D continuous random network glasses. Atomic-resolution electron spectroscopy identifies the glass as SiO2 formed from a bilayer of (SiO4) 2− tetrahedra and without detectable covalent bonding to the graphene. From these images, we directly obtain ring statistics and pair distribution functions that span short-, medium-, and long-range order. Ab initio calculations indicate that van der Waals interactions with graphene energetically stabilizes the 2D structure with respect to bulk SiO2. These results demonstrate a new class of 2D glasses that can be applied in layered graphene devices and studied at the atomic scale.
208 citations
Authors
Showing all 10135 results
Name | H-index | Papers | Citations |
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John B. Goodenough | 151 | 1064 | 113741 |
Ashok Kumar | 151 | 5654 | 164086 |
Anne Lähteenmäki | 116 | 485 | 81977 |
Kalyanmoy Deb | 112 | 713 | 122802 |
Riitta Hari | 111 | 491 | 43873 |
Robin I. M. Dunbar | 111 | 586 | 47498 |
Andreas Richter | 110 | 769 | 48262 |
Mika Sillanpää | 96 | 1019 | 44260 |
Muhammad Farooq | 92 | 1341 | 37533 |
Ivo Babuška | 90 | 376 | 41465 |
Merja Penttilä | 87 | 303 | 22351 |
Andries Meijerink | 87 | 426 | 29335 |
T. Poutanen | 86 | 120 | 33158 |
Sajal K. Das | 85 | 1124 | 29785 |
Kalle Lyytinen | 84 | 426 | 27708 |