Aalto University

About: Aalto University is a education organization based out in Espoo, Finland. It is known for research contribution in the topics: Population & Carbon nanotube. The organization has 9969 authors who have published 32648 publications receiving 829626 citations. The organization is also known as: TKK & Aalto-korkeakoulu.

Pinpointing: Precise Head- and Eye-Based Target Selection for Augmented Reality

Abstract: Head and eye movement can be leveraged to improve the user's interaction repertoire for wearable displays. Head movements are deliberate and accurate, and provide the current state-of-the-art pointing technique. Eye gaze can potentially be faster and more ergonomic, but suffers from low accuracy due to calibration errors and drift of wearable eye-tracking sensors. This work investigates precise, multimodal selection techniques using head motion and eye gaze. A comparison of speed and pointing accuracy reveals the relative merits of each method, including the achievable target size for robust selection. We demonstrate and discuss example applications for augmented reality, including compact menus with deep structure, and a proof-of-concept method for on-line correction of calibration drift.

EASE: EPC as a service to ease mobile core network deployment over cloud

Abstract: The objective of this article is to demonstrate the feasibility of on-demand creation of cloud-based elastic mobile core networks, along with their lifecycle management. For this purpose the article describes the key elements to realize the architectural vision of EPC as a Service, an implementation option of the Evolved Packet Core, as specified by 3GPP, which can be deployed in cloud environments. To meet several challenging requirements associated with the implementation of EPC over a cloud infrastructure and providing it "as a Service," this article presents a number of different options, each with different characteristics, advantages, and disadvantages. A thorough analysis comparing the different implementation options is also presented.

Understanding innovation in practice: a discussion of the production and re-production of Nordic Walking

Abstract: Building on the work of those who have highlighted the role of consumers and lead users we focus on innovations not in products but in what people do. In developing a method of conceptualising the emergence and reproduction of practice we argue that innovation is not a one-off moment but a continuous on-going process. Specifically, we suggest that innovations in practice involve changing combinations of symbolic and material ingredients and of competence or know-how. In addition, we argue that managers, manufacturers and consumers are all variously involved in making and sustaining connections between these defining elements. We illustrate and elaborate on these ideas with reference to Nordic Walking, a form of speed walking with two sticks. First practiced in 1997, it is now a regular pursuit for more than seven million people in over 30 countries and is reputed to be Europe's fastest growing form of exercise. In discussing this case we specify the constitutive ingredients of Nordic Walking and its locat...

Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease

Abstract: Gut microbiome dysbiosis has been demonstrated in subjects with newly diagnosed and chronic inflammatory bowel disease (IBD). In this study we sought to explore longitudinal changes in dysbiosis and ascertain associations between dysbiosis and markers of disease activity and treatment outcome. We performed a prospective cohort study of 19 treatment-naive pediatric IBD subjects and 10 healthy controls, measuring fecal calprotectin and assessing the gut microbiome via repeated stool samples. Associations between clinical characteristics and the microbiome were tested using generalized estimating equations. Random forest classification was used to predict ultimate treatment response (presence of mucosal healing at follow-up colonoscopy) or non-response using patients’ pretreatment samples. Patients with Crohn’s disease had increased markers of inflammation and dysbiosis compared to controls. Patients with ulcerative colitis had even higher inflammation and dysbiosis compared to those with Crohn’s disease. For all cases, the gut microbial dysbiosis index associated significantly with clinical and biological measures of disease severity, but did not associate with treatment response. We found differences in specific gut microbiome genera between cases/controls and responders/non-responders including Akkermansia, Coprococcus, Fusobacterium, Veillonella, Faecalibacterium, and Adlercreutzia. Using pretreatment microbiome data in a weighted random forest classifier, we were able to obtain 76.5 % accuracy for prediction of responder status. Patient dysbiosis improved over time but persisted even among those who responded to treatment and achieved mucosal healing. Although dysbiosis index was not significantly different between responders and non-responders, we found specific genus-level differences. We found that pretreatment microbiome signatures are a promising avenue for prediction of remission and response to treatment.