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Institution

Academia Sinica

FacilityTaipei, Taiwan
About: Academia Sinica is a facility organization based out in Taipei, Taiwan. It is known for research contribution in the topics: Population & Galaxy. The organization has 52086 authors who have published 65998 publications receiving 1728114 citations. The organization is also known as: Central Research Academy.


Papers
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Journal ArticleDOI
Du Jin-Guan1, Li Yuan
TL;DR: In this article, the existence and ergodic properties of the integer-valued autoregressive model with lag p dependence were proved and it was shown that the correlation structure of the INAR model is similar to that of the continuous-valued auto-regression process.
Abstract: . The integer-valued autoregressive (INAR) model with lag p dependence is discussed. The existence and ergodic property of the INAR model are proved. It is shown that the correlation structure of the INAR model is similar to that of the continuous-valued autoregressive (AR) process, and the stationary conditions of INAR and AR processes are also the same.

340 citations

Journal ArticleDOI
TL;DR: It is hoped that with more systematic investigations based on clinical isolates and human cell lines, the true significance of LAM in the immunopathogenesis of tuberculosis and leprosy can eventually be explained.
Abstract: Detailed structural and functional studies over the last decade have led to current recognition of the mycobacterial lipoarabinomannan (LAM) as a phosphatidylinositol anchored lipoglycan with diverse biological activities. Fatty acylation has been demonstrated to be essential for LAM to maintain its functional integrity although the focus has largely been on the arabinan motifs and the terminal capping function. It has recently been shown that the mannose caps may be involved not only in attenuating host immune response, but also in mediating the binding of mycobacteria to and subsequent entry into macrophages. This may further be linked to an intracellular trafficking pathway through which LAM is thought to be presented by CD1 to subsets of T-cells. The implication of LAM as major histocompatibility complex (MHC)-independent T-cell epitope and the ensuing immune response is an area of intensive studies. Another recent focus of research is the biosynthesis of arabinan which has been shown to be inhibitable by the anti-tuberculosis drug, ethambutol. The phenomenon of truncated LAM as synthesized by ethambutol resistant strains provides an invaluable handle for dissecting the array of arabinosyltransferases involved, as well as generating much needed structural variants for further structural and functional studies. It is hoped that with more systematic investigations based on clinical isolates and human cell lines, the true significance of LAM in the immunopathogenesis of tuberculosis and leprosy can eventually be explained.

339 citations

Journal ArticleDOI
TL;DR: In this paper, the complex refractive index of chemical-vapor-deposited monolayer transition metal dichalcogenides (TMDs) was characterized using spectroscopic ellipsometry, showing a strong correlation between the magnitude of the exciton binding energy and band gap energy.
Abstract: Spectroscopic ellipsometry was used to characterize the complex refractive index of chemical-vapor-deposited monolayer transition metal dichalcogenides (TMDs). The extraordinary large value of the refractive index in the visible frequency range is obtained. The absorption response shows a strong correlation between the magnitude of the exciton binding energy and band gap energy. Together with the observed giant spin-orbit splitting, these findings advance the fundamental understanding of their novel electronic structures and the development of monolayer TMDs-based optoelectronic and spintronic devices.

339 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, S. Abdel Khalek4  +2911 moreInstitutions (209)
TL;DR: In this paper, a measurement of the Z/gamma* boson transverse momentum spectrum using ATLAS proton-proton collision data at a centre-of-mass energy of root s = 7TeV at the LHC is described.
Abstract: This paper describes a measurement of the Z/gamma* boson transverse momentum spectrum using ATLAS proton-proton collision data at a centre-of-mass energy of root s = 7TeV at the LHC. The measurement is performed in the Z/gamma* -> e(+)e(-) and Z/gamma* -> mu(+)mu(-) channels, using data corresponding to an integrated luminosity of 4.7 fb(-1). Normalized differential cross sections as a function of the Z/gamma* boson transverse momentum are measured for transverse momenta up to 800 GeV. The measurement is performed inclusively for Z/gamma* rapidities up to 2.4, as well as in three rapidity bins. The channel results are combined, compared to perturbative and resummed QCD calculations and used to constrain the parton shower parameters of Monte Carlo generators.

339 citations

Journal ArticleDOI
TL;DR: An innovative biochemical pathway involving pyruvate orthophosphate dikinase in generating asparagine for nitrogen remobilization in dark-treated leaves is postulated by monitoring the gene expression patterns at carefully chosen time points and plotting the molecular events occurring in the processes examined.
Abstract: Senescence is the final stage of leaf development. Although it means the loss of vitality of leaf tissue, leaf senescence is tightly controlled by the development to increase the fitness of the whole plant. The molecular mechanisms regulating the induction and progression of leaf senescence are complex. We used a cDNA microarray, containing 11 500 Arabidopsis DNA elements, and the whole-genome Arabidopsis ATH1 Genome Array to examine global gene expression in dark-induced leaf senescence. By monitoring the gene expression patterns at carefully chosen time points, with three biological replicates each time, we identified thousands of up- or down-regulated genes involved in dark-induced senescence. These genes were clustered and categorized according to their expression patterns and responsiveness to dark treatment. Genes with different expression kinetics were classified according to different biological processes. Genes showing significant alteration of expression patterns in all available biochemical pathways were plotted to envision the molecular events occurring in the processes examined. With the expression data, we postulated an innovative biochemical pathway involving pyruvate orthophosphate dikinase in generating asparagine for nitrogen remobilization in dark-treated leaves. We also surveyed the alteration in expression of Arabidopsis transcription factor genes and established an apparent association of GRAS, bZIP, WRKY, NAC, and C2H2 transcription factor families with leaf senescence.

339 citations


Authors

Showing all 52129 results

NameH-indexPapersCitations
Yi Chen2174342293080
Jing Wang1844046202769
Jie Zhang1784857221720
Hyun-Chul Kim1764076183227
Yang Yang1642704144071
Yuh Nung Jan16246074818
Jongmin Lee1502257134772
Hui-Ming Cheng147880111921
Teruki Kamon1422034115633
Jian Yang1421818111166
I. V. Gorelov1391916103133
S. R. Hou1391845106563
Kaori Maeshima1391850105218
Jiangyong Jia138117391163
Kenneth Bloom1381958110129
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202315
2022111
20212,414
20202,356
20192,330
20182,349