Institution
Academia Sinica
Facility•Taipei, Taiwan•
About: Academia Sinica is a facility organization based out in Taipei, Taiwan. It is known for research contribution in the topics: Population & Gene. The organization has 52086 authors who have published 65998 publications receiving 1728114 citations. The organization is also known as: Central Research Academy.
Topics: Population, Gene, Galaxy, Catalysis, Large Hadron Collider
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors studied the asymptotoc behavior of a predator-prey model with stage structure and found that an orbitally asmptotically stable periodic orbit exists in that model.
Abstract: This paper studies the asymptotoc behavior of a predator-prey model with stage structure. It is found that an orbitally asymptotically stable periodic orbit exists in that model. When time delay due to gestation of predator and time delay from crowding effect of prey are incorporated, we establish the condition for the permanence of populations and sufficient conditions under which positive equilibrium of the model is globally stable.
296 citations
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TL;DR: A more comprehensive analysis of Scleractinia and various outgroups, based on two mitochondrial genes and analyses of nuclear genes of a subset of taxa to test unexpected relationships, suggests a future of greater taxonomic stability.
Abstract: Modern hard corals (Class Hexacorallia; Order Scleractinia) are widely studied because of their fundamental role in reef building and their superb fossil record extending back to the Triassic. Nevertheless, interpretations of their evolutionary relationships have been in flux for over a decade. Recent analyses undermine the legitimacy of traditional suborders, families and genera, and suggest that a non-skeletal sister clade (Order Corallimorpharia) might be imbedded within the stony corals. However, these studies either sampled a relatively limited array of taxa or assembled trees from heterogeneous data sets. Here we provide a more comprehensive analysis of Scleractinia (127 species, 75 genera, 17 families) and various outgroups, based on two mitochondrial genes (cytochrome oxidase I, cytochrome b), with analyses of nuclear genes (s-tubulin, ribosomal DNA) of a subset of taxa to test unexpected relationships. Eleven of 16 families were found to be polyphyletic. Strikingly, over one third of all families as conventionally defined contain representatives from the highly divergent “robust” and “complex” clades. However, the recent suggestion that corallimorpharians are true corals that have lost their skeletons was not upheld. Relationships were supported not only by mitochondrial and nuclear genes, but also often by morphological characters which had been ignored or never noted previously. The concordance of molecular characters and more carefully examined morphological characters suggests a future of greater taxonomic stability, as well as the potential to trace the evolutionary history of this ecologically important group using fossils.
296 citations
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TL;DR: Two sox9 genes are cloned from zebrafish two loci reside on chromosome segments that were apparently duplicated in a large-scale genomic duplication event in ray fin fish phylogeny and both Sox9a and Sox9b proteins bind to the HMG consensus DNA sequences in vitro.
296 citations
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National University of Singapore1, Agency for Science, Technology and Research2, University of Amsterdam3, Academia Sinica4, University of California, San Diego5, Boston Children's Hospital6, Imperial College London7, University of Toronto8, University of Melbourne9, University of Sydney10, Singapore National Eye Center11, University of Florence12, Université de Montréal13, University of Hong Kong14, Fudan University15, University of Ulsan16, University of Western Australia17, Royal Children's Hospital18, Ewha Womans University19, Korea University20, Chung-Ang University21, Catholic University of Korea22, Inje University23, Pusan National University24, Yonsei University25, China Medical University (Taiwan)26, Chang Gung University27, Mackay Memorial Hospital28, National Taiwan University29, Taipei Municipal YangMing Hospital30, Royal Perth Hospital31, University of Adelaide32, University of Queensland33, University College London34, Royal London Hospital35, University Hospitals Bristol NHS Foundation Trust36, North-West University37, Harvard University38, Northwestern University39, University of Southern California40, Moorfields Eye Hospital41
TL;DR: The involvement of the FCGR2A locus may have implications for understanding immune activation in Kawasaki disease pathogenesis and the mechanism of response to intravenous immunoglobulin, the only proven therapy for this disease.
Abstract: Kawasaki disease is a systemic vasculitis of unknown etiology, with clinical observations suggesting a substantial genetic contribution to disease susceptibility. We conducted a genome-wide association study and replication analysis in 2,173 individuals with Kawasaki disease and 9,383 controls from five independent sample collections. Two loci exceeded the formal threshold for genome-wide significance. The first locus is a functional polymorphism in the IgG receptor gene FCGR2A (encoding an H131R substitution) (rs1801274; P = 7.35 × 10(-11), odds ratio (OR) = 1.32), with the A allele (coding for histadine) conferring elevated disease risk. The second locus is at 19q13, (P = 2.51 × 10(-9), OR = 1.42 for the rs2233152 SNP near MIA and RAB4B; P = 1.68 × 10(-12), OR = 1.52 for rs28493229 in ITPKC), which confirms previous findings(1). The involvement of the FCGR2A locus may have implications for understanding immune activation in Kawasaki disease pathogenesis and the mechanism of response to intravenous immunoglobulin, the only proven therapy for this disease.
295 citations
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TL;DR: In this article, the authors presented a highly sensitive and accurate method for quantitative detection and characterization of noninteracting or weakly interacting uniaxial single domain particles (UNISD) in rocks and sediments.
Abstract: We present a highly sensitive and accurate method for quantitative detection and characterization of noninteracting or weakly interacting uniaxial single domain particles (UNISD) in rocks and sediments. The method is based on high-resolution measurements of first-order reversal curves (FORCs). UNISD particles have a unique FORC signature that can be used to isolate their contribution among other magnetic components. This signature has a narrow ridge along the Hc axis of the FORC diagram, called the central ridge, which is proportional to the switching field distribution of the particles. Therefore, the central ridge is directly comparable with other magnetic measurements, such as remanent magnetization curves, with the advantage of being fully selective to SD particles, rather than other magnetic components. This selectivity is unmatched by other magnetic unmixing methods, and offers useful applications ranging from characterization of SD particles for paleointensity studies to detecting magnetofossils and ultrafine authigenically precipitated minerals in sediments.
295 citations
Authors
Showing all 52129 results
Name | H-index | Papers | Citations |
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Yi Chen | 217 | 4342 | 293080 |
Jing Wang | 184 | 4046 | 202769 |
Jie Zhang | 178 | 4857 | 221720 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
Yang Yang | 164 | 2704 | 144071 |
Yuh Nung Jan | 162 | 460 | 74818 |
Jongmin Lee | 150 | 2257 | 134772 |
Hui-Ming Cheng | 147 | 880 | 111921 |
Teruki Kamon | 142 | 2034 | 115633 |
Jian Yang | 142 | 1818 | 111166 |
I. V. Gorelov | 139 | 1916 | 103133 |
S. R. Hou | 139 | 1845 | 106563 |
Kaori Maeshima | 139 | 1850 | 105218 |
Jiangyong Jia | 138 | 1173 | 91163 |
Kenneth Bloom | 138 | 1958 | 110129 |