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Institution

ACADIA Pharmaceuticals Inc.

CompanySan Diego, California, United States
About: ACADIA Pharmaceuticals Inc. is a company organization based out in San Diego, California, United States. It is known for research contribution in the topics: Pimavanserin & Receptor. The organization has 260 authors who have published 276 publications receiving 8418 citations.


Papers
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Journal ArticleDOI
TL;DR: This review compares the pharmacological properties of NDMC to those of clozapine and considers whether NDMC, in its own right, might be a superior antipsychotic drug.

95 citations

Journal ArticleDOI
TL;DR: The present study indicates that βCCt is capable of antagonizing the reinforcing and the sedative properties of alcohol and may represent a prototype of a pharmacotherapeutic agent to effectively reduce alcohol drinking behavior in human alcoholics.

94 citations

Journal ArticleDOI
TL;DR: Data indicate that m-calpain protein is lost very early after axonal injury, and likely reflect activation and degradation of this protein long before the cytoskeleton is degraded.

88 citations

Journal ArticleDOI
TL;DR: Results suggest that TM6 is a switch that defines the activation state of the receptor, and that ligand interactions with TM6 stabilize the receptor in either an active or an inactive conformation.

88 citations

Journal ArticleDOI
TL;DR: A general, high yielding rapid iron-catalyzed cross-coupling reaction between Grignard reagents and imidoyl chlorides is described, resulting in high yields of 71-96% using 5% iron catalyst in a THF-NMP solvent mixture.

85 citations


Authors

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Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
202119
202016
20196
20188
20176