Adama University

About: Adama University is a education organization based out in Nazrēt, Ethiopia. It is known for research contribution in the topics: Population & Adsorption. The organization has 840 authors who have published 1010 publications receiving 5547 citations. The organization is also known as: Adama Science and Technology University & ቴክኖሎጂ ዩኒቨርሲቲ, አዳማ ሳይንስና ቴክኖሎጂ ዩኒቨርሲቲ.

An Examination of the Impact of Power Sector Reform on Manufacturing and Services Sector in Nigeria: an Empirical Analysis

Abstract: The main objective of this study is to empirically examine the impact of Power Sector Reform on Manufacturing and Services Sector in Nigeria between 1999-2016. The study employed secondary annual time series data sourced from World Bank database (2016). The methodology adopted for the study was Augmented Dickey-Fuller (ADF); a test for long-run relationship using ARDL Bounds Testing approach with analysis of long-run and short-run dynamics in the model. A striking revelation from the study is the inverse relationship that exists between manufacturing output and electricity consumption in Nigeria within the period referenced. This negative relationship is not unconnected with widespread allegation of misappropriation of budgeted funds for the Power Sector by successive administrations in Nigeria since 1999. It must be stated in clear terms that constant and consistent electricity generation, transmission and distribution is sine-qua-none for the growth of the national economy. Virtually all sectors of the economy depend on the supply of electricity to do business and so the lack of this vital ingredient of growth contributes in no small measure in stagnating economic growth and development. Efforts at reforming the power sector can only be fruitful when ALL stakeholders in the power sector including the political class put away their personal agendas and take the bull by the horn towards rescuing the nation from the looming danger of stagnant economic growth. Furthermore, there is the need for the Nigerian government to come up with new, better and alternative ways of improving energy generation and supply, as well as proper maintenance of electricity infrastructure in the country.

Comparative Appraisal of some Specification Error Test

Abstract: This research work compared the power of some specification error test using bootstrapping experiment to generate the data for each of the models at different sample sizes (n) 20, 30, 50, and 80 respectively, each with 100 replications(r). The models in this research consist of three omitted variables. For the models considered, the experiment reveals that the Ramsey Regression Equation Specification Error Test (RESET test) is more efficient than that of Q test in detecting the error of omitted variable in specification error.

Molecular docking analysis of antibacterial indole alkaloids from roots of Brucea antidysentrica

Abstract: Brucea antidysentrica is one of the medicinal plants used traditionally to treat various diseases such as leprosy, wound, diarrhea, fever, eye disease, rabies and tumor/cancer. Phytochemical screening test of dichloromethane/methanol (1:1) and methanol extracts revealed the presence of alkaloids, tannins, flavonoids, steroids and saponins, terpenoids, and phytosterols. Silica gel column chromatographic separation of dichloromethane/methanol (1:1) and acid-base extracts afforded compound 1, canthin-6-one (2) and 1,11-dimethoxycanthin-6-one (3). The crude extracts and isolated compounds were screened for in vitro antibacterial activity against strains of Salmonella thphimurium, Escherichia coli, Bacillus subtilis and Staphylococcus aureus. Canthin-6-one (2) and 1,11-dimethoxycanthin-6-one (3) exhibited promising antibacterial activity against E. coli and S. thphimurium (12.6±0.6 and 12.5±0.87 mm zone of inhibition, respectively) compared to ciprofloxacin (27.3±2.52 and 29±1.00 mm, respectively), at 0.5 mg/mL. The radical scavenging activity of dichloromethane/methanol (1:1) and acid-base extract were 83.3 % and 80 %, respectively, whereas alkaloids 1-3 displayed activity of 85.3 %, 87.5 % and 78.4 % at 100 µg/mL, respectively, suggesting that canthin-6-one (2) displayed promising radical scavenging activity. The molecular docking analysis showed compound 1 and 1,11-dimethoxycanthin-6-one (3) were found to show hydrogen bond interaction with active site amino acid residue PHE196 and ALA 51 at a distance of 1.5 Ao and 1.5 Ao, respectively. Hydrophobic interactions were observed between 2 and 3 with VAL201, LYS57, GLY200, ASN198, ALA51, LEU52 and ASN198, LEU52, VAL201, LYS57, respectively, suggesting the compounds may act as potential inhibitors of DNA gyrase enzyme.