Adama University

About: Adama University is a education organization based out in Nazrēt, Ethiopia. It is known for research contribution in the topics: Population & Adsorption. The organization has 840 authors who have published 1010 publications receiving 5547 citations. The organization is also known as: Adama Science and Technology University & ቴክኖሎጂ ዩኒቨርሲቲ, አዳማ ሳይንስና ቴክኖሎጂ ዩኒቨርሲቲ.

E-Learning Technology in Pre-Service Teachers Training - Lessons for Ethiopia

Abstract: Dynamic changes in technology can have a profound effect on teacher’s education. With technology evolving at such a rapid rate, it is imperative that teachers training institutions equip teacher trainees with technological skills that are essential for coping in the wider learning community. These skills are most effectively gained by learning with technology, rather than about technology. Despite increasing number of technologies and level of educational technology provided by teacher education programs, effective and high-level integration of technology into learning and teaching processes is not still as expected. The purpose of this review was to ascertain how pre-service teachers training institutions were using an e-learning technology in global context and what factors affected successful implementation of e-learning and how they remedy the barriers, so as to gain lessons for Ethiopia teachers training institutions. More specifically, this review sought to examine the basic features, advantages and disadvantages of e-learning, barriers and its remedy toward the effective utilization of the e-learning techno-pedagogy for quality teachers education. The review results indicated that successful implementation of the e-learning technology in pre-service teachers training was dependent on the four key factors of ICT infrastructure, ICT leadership, support and training initiatives and the teachers’ and trainees ICT capacity. These four factors are not hierarchical in nature, but are all equally important. DOI: 10.5901/jesr.2014.v4n1p159

In silico Molecular Docking, DFT Analysis and ADMET Studies of Carbazole Alkaloid and Coumarins from Roots of Clausena anisata: A Potent Inhibitor for Quorum Sensing.

Abstract: Introduction In modern drug design, in silico methods are largely used to understand drug-receptor interactions and quantum chemical properties In the present study, a computational de novo design approach was used to confirm mode of binding for antibacterial activity, elucidating quantum chemical properties and ADMET-drug-likeness of carbazole alkaloid (1) and three coumarins (2-4) isolated from roots of Clausena anisata Methods Docking studies were performed with DNA-Gyrase (6F86) and LasR binding domain (2UV0) employing a flexible ligand docking approach using AutoDock Vina SwissADME prediction and toxicological predictions were performed by ADMET The optimized structures and molecular electrostatic potential surface of the isolated compounds were predicted by DFT analysis using B3LYP/6-31G basis levels Results and Discussion The docking results revealed that compound 3 showed better docking scores against both DNA gyrase B and LasR binding domain compared with ciprofloxacin with potential as an inhibitor of bacterial DNA gyrase and quorum sensing LasR binding domain The SwissADME prediction results showed that all the isolated compounds (1-4) satisfy Lipinski's rule of five with zero violations Toxicological prediction results suggested that all compounds and ciprofloxacin are non-hepatotoxic, non-carcinogenic, non-irritant, immunogenic, and non-cytotoxic The DFT analysis results revealed that compound 3 has large electronegativity (χeV), global softness (σ eV-1), global electrophilicity (ωeV), and mutagenicity value closer to ciprofloxacin (with LD50 value of 480 mg/kg) suggesting better bioactivity and chemical reactivity with considerable intra-molecular charge transfer between electron-donor to electron-acceptor groups Conclusion Overall, compound 3 may serve as a lead molecule that could be developed into a potent E coli DNA gyrase B inhibitor and efficient inhibitor for quorum sensing auto-inducer LasR binding domain of Pseudomonas aeruginosa

Effects of Azadirachta Indica Leaf Extract, Capping Agents, on the Synthesis of Pure And Cu Doped ZnO-Nanoparticles: A Green Approach and Microbial Activity

Abstract: Abstract The current studies presented the green synthesis of zinc oxide and copper doped ZnO nanoparticles (NPs) using different ratios of Neem leaf extract and its antibacterial application on drug-resistant bacteria. The synthesized NPs were characterized using: X-ray diffractions (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscope (SEM), UV–visible spectroscopy and a simultaneous DTA-TGA thermal analyzer. All the synthesized materials were stable above 400°C. The powder diffraction studies indicated the formation of phase pure materials with wurtzite structure for pure ZnO and 0.5%, 1%, 1.5% Cu doped ZnO with the crystallite size in the range of 16.07 – 23.74 nm. SEM analysis revealed the formation of spherical shaped NPs with large grain size for 10% (v/v) ratio of aqueous leave extract. The aqueous extract of neem act as capping agent and prevent the NPs from agglomeration. The spectral studies confirmed the formation of NPs with the absorbance peak that is different from the micro-size ZnO. The antibacterial activities of the synthesized materials ZnO (1:1) against Staphylococcus aureus and uncalcined ZnO (7:3) and (Zn0.985Cu0.015O) against Bacillus subtilis were enhanced when referenced to the standard gentamicin. Graphical Abstract

Evaluating land-use plan using conformance-based approach in Adama city, Ethiopia

Abstract: Urban land-use plan is regarded as a useful tool to achieve urban sustainable development. However, presently it is unclear that how well the Plan is being implemented and major factors contribute to the variation of its implementation in Adama city, Ethiopia. This research examines the extent to which Land-use plan of Adama city functioned from 2004 to 2014 has guided and controlled all spatial developments during planning period by measuring the degree to which actual land-use outcomes over a 10-year period conform to the Plan intention. Land-uses of the City as of 2004 and 2014 are mapped; conforming, nonconforming, and unfulfilled developments are identified through spatial overlay analysis in geographic information system environment; effectiveness of boundary containment and proposed land sufficiency are explored. The findings demonstrate that although the Plan proposed reasonable area, it has met difficulties to control and guide new spatial developments of housing land-uses followed by social services and total urban growth. The limitation is due to combined result of geographic variables, absence of regular monitoring and evaluation, lack of commitment, and political leadership influence. The study would support sustainable spatial policy and direction of spatial development with respect to sustainable urban environment.