Adeleke University

About: Adeleke University is a education organization based out in Ede, Nigeria. It is known for research contribution in the topics: Docking (molecular) & Oxidative stress. The organization has 138 authors who have published 171 publications receiving 545 citations.

Biosynthesis, characterization and antimicrobial activity of gold nanoparticles from leaf extracts of Annona muricata

Abstract: The need to divulge the rapid synthesis, non-hazardous, cost effectiveness and eco-friendly methods for the synthesis of nanoparticles utilizing plants is of great importance. This is as a result of high toxicity associated with the chemical method of synthesizing nanoparticles. The aim of this study was to investigate the potency of the synthesized gold nanoparticle against selected human pathogens. Gold nanoparticles were synthesized by reacting 1 mM gold chloride solution with leaf extract of Annona muricata. The synthesized gold nanoparticles were characterized with UV–visible spectrophotometer, transmission electron microscope (TEM) and Fourier transformed infrared spectroscopy (FTIR). The antibacterial and antifungal activities of the synthesized gold nanoparticles were also investigated. The morphology, size, and structural properties of synthesized gold nanoparticles were determined with TEM analysis which showed spherical mono-dispersed structure with an average particle size of 25.5 nm. FTIR analysis reveal band at 3271.14, 2111.91 and 1637.82 cm−1 corresponding to –N–H, –C=C, and –C–N functional groups that are responsible for the capping and stabilization of synthesized gold nanoparticles. The effectiveness of the gold nanoparticle against the test pathogens increases as the concentration of gold nanoparticle increases. The percentage of zones of inhibition of synthesized gold nanoparticle against test fungi and bacteria ranges from 30 to 66% and 40 to 54%, respectively. The potency of the synthesized gold nanoparticle against the selected fungi and bacteria increases with increase in concentration of gold nanoparticle. Therefore, the antibacterial and antifungal investigation revealed that the synthesized gold nanoparticles exhibited good antimicrobial activity.

Automatic system for grading banana using GLCM texture feature extraction and neural network arbitrations

Abstract: Nowadays, an identification system is needed in the food processing industries to boost the efficiency of production so as to meet up with demand in the society. Manual approach is often used in product grading and quality control, and this unfortunately could lead to uneven products, higher time expense, and fatigue by the human operators. Therefore, we propose in this article, an automatic system for classification of banana whether it is healthy for production or not. Such a system is faster, accurate and also relieves the stress that an operator may have. Our system uses GLCM texture feature analysis to extract the features required for training and testing three classification models; namely, radial basis function (RBF), support vector machine (SVM), and backpropagation neural network (ANN). A classification performance comparison is drawn between the different classification models, and the obtained experimental results indicate that such intelligent grading systems may be efficiently used in real life applications for similar tasks in food processing industries. Practical applications The Automatic system is highly needed in food processing industries to meet up with the production of food products required in the societies. Healthy food products are needed in the society and this can be achieved by implementing a system that will enhance in the sorting or grading of the raw materials (such as banana) used in food processing industries. This system is accurate, economical, and faster in achieving the best product. Such a system will make the product be readily available in the market i.e. meeting the need of the people.

The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus

Abstract: Diabetes mellitus is a metabolic disease that can lead to high morbidity, mortality and long-term complications. Available treatment strategies, which are mainly based on treating hyperglycemia, with insulin and other pharmacological agents are not completely efficient and can even lead to development of unwanted side effects. Scientific evidence suggests that bioactive compounds from teas and other plant-based foods, which are known source of natural antioxidants, could be an attractive strategy to preferentially treat and manage type 2 diabetes mellitus (T2DM) and thus, have significant therapeutic implications. In this review, we attempt an in-depth analysis and discussion of the current progress in our understanding of the antidiabetic potential of two commercialized South Africa herbal tisanes—Rooibos and Honeybush and their polyphenols.