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Institution

Agilent Technologies

CompanySanta Clara, California, United States
About: Agilent Technologies is a company organization based out in Santa Clara, California, United States. It is known for research contribution in the topics: Signal & Mass spectrometry. The organization has 7398 authors who have published 11518 publications receiving 262410 citations. The organization is also known as: Agilent Technologies, Inc..


Papers
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Journal ArticleDOI
TL;DR: Aqueous normal-phase chromatography was used for the analysis of metabolites in human saliva and urine samples and the reproducibility of retention of individual metabolites in these complex matrices was tested for several compounds.
Abstract: Aqueous normal-phase chromatography was used for the analysis of metabolites in human saliva and urine samples. The column was packed with a silica hydride type separation material. Several gradients were tested with different mobile phase additives in order to produce retention for amino acids, small organic acids, and carbohydrates. Detection was done by TOF MS. In some cases the relative concentration levels of various metabolites in human saliva were compared for normal patients and patients with pancreatic cancer or pancreatitis. The reproducibility of retention of individual metabolites in these complex matrices was tested for several compounds.

65 citations

Journal ArticleDOI
TL;DR: By extending the approach to ultra high frequencies, an acoustic microscope has been developed that is capable of operation at gigahertz frequency and micron length scales, allowing full calibration and determination of phases to within a single arbitrary constant.
Abstract: A full-field view laser ultrasonic imaging method has been developed that measures acoustic motion at a surface without scanning. Images are recorded at normal video frame rates by using dynamic holography with photorefractive interferometric detection. By extending the approach to ultra high frequencies, an acoustic microscope has been developed that is capable of operation at gigahertz frequency and micron length scales. Both acoustic amplitude and phase are recorded, allowing full calibration and determination of phases to within a single arbitrary constant. Results are presented of measurements at frequencies of 800-900 MHz, illustrating a multitude of normal mode behavior in electrically driven thin film acoustic resonators. Coupled with microwave electrical impedance measurements, this imaging mode provides an exceptionally fast method for evaluation of electric-to-acoustic coupling of these devices and their performance. Images of 256 /spl times/ 240 pixels are recorded at 18 fps rates synchronized to obtain both in-phase and quadrature detection of the acoustic motion. Simple averaging provides sensitivity to the subnanometer level at each pixel calibrated over the image using interferometry. Identification of specific acoustic modes and their relationship to electrical impedance characteristics show the advantages and overall high speed of the technique.

65 citations

Proceedings ArticleDOI
28 Apr 2002
TL;DR: It is shown that the mentioned test approaches can result in a significant and scalable reduction of the Cost of Test.
Abstract: Test approaches that can be combined with multisite, like reduced pin-count test, low channel cost ATE, and bandwidth matching, are becoming pervasive. Yet their economic benefits, the tradeoffs, and the long-term scalability of their benefits during technology progress, are not well understood In this paper the benefits and tradeoffs will be analyzed using technical cost modeling. The dependency of the benefits on the application are analyzed by modeling the test cost for 4 different applications. It is shown that the mentioned test approaches can result in a significant and scalable reduction of the Cost of Test.

65 citations

Journal ArticleDOI
01 Jun 2000
TL;DR: The story is told of how the Unified Cordic algorithm came to be developed, starting from an idea in the mind of a student and culminating in a product, a patent, a paper, a motorcade, and an award.
Abstract: The story is told of how the Unified Cordic algorithm came to be developed, starting from an idea in the mind of a student and culminating in a product, a patent, a paper, a motorcade, and an award Along the way, a unified algorithm for generating the elementary functions and the math co-processor industry in Silicon Valley were born

65 citations

Journal ArticleDOI
TL;DR: In this paper, a sensitive and highly selective methodology for the determination of a wide range of pesticides, based on the simultaneous element-specific determination of phosphorus, sulfur, chloride, bromine and iodine by gas chromatography hyphenated with octopole reaction cell-inductively coupled plasma mass spectrometry (GC-CC-ICP-MS) is described.
Abstract: A sensitive and highly selective methodology for the determination of a wide range of pesticides, based on the simultaneous element-specific determination of phosphorus, sulfur, chloride, bromine and iodine by gas chromatography hyphenated with octopole reaction cell-inductively coupled plasma mass spectrometry (GC-CC-ICP-MS) is described. The chromatographic system was optimised for separation efficiency and short run times and was coupled via a commercially available interface with an octopole reaction cell ICP-MS system which is equipped with an on-axis collision cell. Instrumental settings were optimised with respect to high sensitivity for the target nuclides 31P, 32S, 35Cl, 79Br and 127I and minimized background levels especially for the ions most affected by interferences, such as 31P+, 32S+. Helium and nitrogen were tested as additional plasma gases for possible sensitivity enhancement of the element-specific detection resulting from improved ionisation processes inside the plasma. Due to the multi-element capability of the instrumental setup and the good accuracy of the retention times that were achieved, identification of the detected pesticides can be carried out using their retention times, the element compositions and element ratios present in each chromatographic peak. For the different pesticides detection limits down to the ppt level or the low ppb level were obtained. The average RSDs of the retention times and the peak areas were better than 0.8% and 8%, respectively. The analytical methodology developed has been applied to the screening of different fruit extracts for pesticides. Peaks were identified by comparison of the retention times obtained and by their elemental composition. Quantitative results have been obtained both by external calibration and by using a compound independent calibration.

65 citations


Authors

Showing all 7402 results

NameH-indexPapersCitations
Hongjie Dai197570182579
Zhuang Liu14953587662
Jie Liu131153168891
Thomas Quertermous10340552437
John E. Bowers102176749290
Roy G. Gordon8944931058
Masaru Tomita7667740415
Stuart Lindsay7434722224
Ron Shamir7431923670
W. Richard McCombie7114464155
Tomoyoshi Soga7139221209
Michael R. Krames6532118448
Shabaz Mohammed6418817254
Geert Leus6260919492
Giuseppe Gigli6154115159
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
20228
2021142
2020157
2019168
2018164