Agilent Technologies

About: Agilent Technologies is a company organization based out in Santa Clara, California, United States. It is known for research contribution in the topics: Signal & Mass spectrometry. The organization has 7398 authors who have published 11518 publications receiving 262410 citations. The organization is also known as: Agilent Technologies, Inc..

Open-loop laser driver having an integrated digital controller

Abstract: A laser driver for generating drive waveforms that are suitable for driving a single VCSEL or an array of VCSELs. A digital controller is integrated into the laser driver and is utilized to initially program and selectively adjust during the operation of the driver one or more of the following VCSEL drive waveform parameters: (1) bias current, (2) modulation current, (3) negative peaking depth, and (4) negative peaking duration. The laser driver has an aging compensation mechanism for monitoring the age of the laser and for selectively adjusting the dc and ac parameters of the VCSEL drive waveform to compensate for the aging of the laser. The laser driver also has a temperature compensation mechanism for monitoring the temperature of the driver IC and selectively adjusting the dc and ac parameters of the VCSEL drive waveform to compensate for the changes in temperature.

Improved transparent, flexible permeability barrier for organic electroluminescent devices

Abstract: A barrier for preventing water or oxygen from a source thereof from reaching a device that is sensitive to water or oxygen. The barrier is constructed by depositing a first polymer layer[191] between the device and the source. An inorganic layer[192] is deposited on the first polymer layer[191] the device by plasma enhanced chemical vapor deposition utilizing an electron cyclotron resonance source ECR-PECVD. A second polymer layer[193] is then deposited on the inorganic layer[192]. The inorganic layer[192] is preferably an oxide or nitride. A second barrier layer[201] having a compound that absorbs oxygen or water can be placed between the inorganic layer[192] and the device to further retard the passage of oxygen or water. The present invention is particularly useful in encapsulating electroluminescent displays[100, 203].

Single‐crystal diffraction at the Extreme Conditions beamline P02.2: procedure for collecting and analyzing high‐pressure single‐crystal data

Abstract: Fast detectors employed at third-generation synchrotrons have reduced collection times significantly and require the optimization of commercial as well as customized software packages for data reduction and analysis. In this paper a procedure to collect, process and analyze single-crystal data sets collected at high pressure at the Extreme Conditions beamline (P02.2) at PETRA III, DESY, is presented. A new data image format called `Esperanto' is introduced that is supported by the commercial software package CrysAlisPro (Agilent Technologies UK Ltd). The new format acts as a vehicle to transform the most common area-detector data formats via a translator software. Such a conversion tool has been developed and converts tiff data collected on a Perkin Elmer detector, as well as data collected on a MAR345/555, to be imported into the CrysAlisPro software. In order to demonstrate the validity of the new approach, a complete structure refinement of boron-mullite (Al5BO9) collected at a pressure of 19.4 (2) GPa is presented. Details pertaining to the data collections and refinements of B-mullite are presented.

Chip-Based Enrichment and NanoLC−MS/MS Analysis of Phosphopeptides from Whole Lysates

Abstract: Protein phosphorylation may be the most widespread and possibly most important post-translational modification (PTM). Considering such a claim, it should be no surprise that huge efforts have been made to improve methods to allow comprehensive study of cellular phosphorylation events. Nevertheless, comprehensive identification of sites of protein phosphorylation is still a challenge, best left to experienced proteomics experts. Recent advances in HPLC chip manufacturing have created an environment to allow automation of popular techniques in the bioanalytical world. One such tool that would benefit from the increased ease and confidence brought by automated 'nanoflow' analysis is phosphopeptide enrichment. To this end, we have developed a reusable HPLC nanoflow rate chip using TiO 2 particles for selective phosphopeptide enrichment. Such a design proved robust, easy to use, and was capable of consistent performance over tens of analyses including minute amounts of complex cellular lysates.