Agilent Technologies

About: Agilent Technologies is a company organization based out in Santa Clara, California, United States. It is known for research contribution in the topics: Signal & Mass spectrometry. The organization has 7398 authors who have published 11518 publications receiving 262410 citations. The organization is also known as: Agilent Technologies, Inc..

White-light-emitting diodes for illumination

Abstract: White light for illumination can be produced from LEDs either by combining red, green and blue emitting chips in one lamp, or by using phosphors to down-convert the emission of short wavelength emitting InGaN LEDs. Both concepts will be critically reviewed, and simulations compared with experimental evaluations. As expected, each solution has advantages, but also drawbacks, which are weighted by the specifics of the applications. The overall picture strongly depends on the efficiencies of the single color chips, the temperature coefficients of all involved materials, and the wanted light output per lamp.

Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID-19 pneumonia.

Abstract: In patients infected by SARS-CoV-2 who experience an exaggerated inflammation leading to pneumonia, monocytes likely play a major role but have received poor attention. Thus, we analyzed peripheral blood monocytes from patients with COVID-19 pneumonia and found that these cells show signs of altered bioenergetics and mitochondrial dysfunction, had a reduced basal and maximal respiration, reduced spare respiratory capacity and decreased proton leak. Basal extracellular acidification rate was also diminished, suggesting reduced capability to perform aerobic glycolysis. Although COVID-19 monocytes had a reduced ability to perform oxidative burst, they were still capable of producing TNF and IFN-g,in vitro. A significantly high amount of monocytes had depolarized mitochondria and abnormal mitochondrial ultrastructure. A redistribution of monocyte subsets, with a significant expansion of intermediate/pro-inflammatory cells, and high amounts of immature monocytes were found, along with a concomitant compression of classical monocytes, and an increased expression of inhibitory checkpoints like PD-1/PD-L1. High plasma levels of several inflammatory cytokines and chemokines, including GM-CSF, IL-18, CCL2, CXCL10 and osteopontin, finally confirm the importance of monocytes in COVID-19 immunopathogenesis.

Probe device having a clip-on wireless system for extending probe tip functionality

Abstract: A probe device is provided that has a clip-on wireless device attached thereto for communicating over a wireless communication link with test equipment having a wireless transceiver attached thereto. The clip-on wireless device may have one or more components that provide additional functionality to the probe device over that which is currently available on most probe devices. Such components may include, for example, run/stop buttons, activity indicators, “headlight” LEDs, etc

Bulk acoustic resonator perimeter reflection system

Abstract: A bulk acoustic resonator having a high quality factor is formed on a substrate having a depression formed in a top surface of the substrate. The resonator includes a first electrode, a piezoelectric material and a second electrode. The first electrode is disposed on the top surface of the substrate and extends beyond the edges of the depression by a first distance to define a first region therebetween. The piezoelectric material is disposed on the top surface of the substrate and over the first electrode, and the second electrode is disposed on the piezoelectric material. The second electrode includes a portion that is located above the depression. The portion of the second electrode that is located over the depression has at least one edge that is offset from a corresponding edge of the depression by a second distance to define a second region therebetween. The first and second regions have different impedances, as a result of the different materials located in the two regions. In addition, the first and second distances are approximately equal to a quarter-wavelength of a sound wave travelling laterally across the respective region, such that reflections off of the edges of the regions constructively interfere to maximize the reflectivity of the resonator.