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Institution

Agilent Technologies

CompanySanta Clara, California, United States
About: Agilent Technologies is a company organization based out in Santa Clara, California, United States. It is known for research contribution in the topics: Signal & Mass spectrometry. The organization has 7398 authors who have published 11518 publications receiving 262410 citations. The organization is also known as: Agilent Technologies, Inc..


Papers
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Patent
26 Aug 1999
TL;DR: A light source constructed from a two-dimensional array of light emitting devices is described in this article, where a color conversion compound absorbs this light and re-emits it in the green region of the optical spectrum.
Abstract: A light source constructed from a two dimensional array of light emitting devices. The light emitting devices include first, second and third types of light emitter. The first type of light emitting device covers a first area in the two dimensional array and emits light in a first region of the optical spectrum. The second type of light emitting device covers a second area in the two dimensional array and emits light in a second region of the optical spectrum, and the third type of light emitting device covers a third area in the two dimensional array and emits light in a third region of the optical spectrum. The first, second, and third areas are chosen such that the simultaneous output from all emitters generates white light. At least one of the emitter types covers an area larger than that covered by the others. In the preferred embodiment of the present invention, the first type of light emitting device includes a light emitting device that emits light at a wavelength less than the wavelength of a green region of the optical spectrum; a color conversion compound absorbs this light and re-emits it in the green region of the optical spectrum.

104 citations

Journal ArticleDOI
TL;DR: In this paper, the authors examined the satisfaction in and perceived quality of information about one's job, business unit, and company, as well as perceived QoS communicated via different media, and found that lean media most strongly related to quality of urgent news, over and above rich communication.
Abstract: We examined the satisfaction in and perceived quality of information about one’s job, business unit, and company, as well as perceived quality of urgent news (i.e., news about changes in business and generally considered legally sensitive material), communicated via different media. Results from 598 fulltime employees revealed that rich media (e.g., face-to-face) was most related to satisfaction in information about one’s job and business unit and in perceived quality of information from the supervisor; lean media (e.g., company newsletter) was most related to satisfaction in and quality of information from top management, while moderate media (e.g., e-mail) was only significantly related to perceived quality of urgent news. Trust in top management was positively related to satisfaction in and quality of information shared by management. Lean media most strongly related to quality of urgent news, over and above rich communication.

104 citations

Journal ArticleDOI
TL;DR: The behavior of different ERC types was investigated, resulting in several important observations, such as the sample-dependent attributes of performance and the potential of using these control RNAs in a combinatorial fashion.
Abstract: External RNA controls (ERCs), although important for microarray assay performance assessment, have yet to be fully implemented in the research community. As part of the MicroArray Quality Control (MAQC) study, two types of ERCs were implemented and evaluated; one was added to the total RNA in the samples before amplification and labeling; the other was added to the copyRNAs (cRNAs) before hybridization. ERC concentration-response curves were used across multiple commercial microarray platforms to identify problematic assays and potential sources of variation in the analytical process. In addition, the behavior of different ERC types was investigated, resulting in several important observations, such as the sample-dependent attributes of performance and the potential of using these control RNAs in a combinatorial fashion. This multiplatform investigation of the behavior and utility of ERCs provides a basis for articulating specific recommendations for their future use in evaluating assay performance across multiple platforms.

103 citations

Journal ArticleDOI
TL;DR: It is demonstrated that the inhibition of oxidative metabolism in T cells by ETO is independent of its effects on FAO at concentrations exceeding 5 μM, and caution should be used when employing this compound for studies in cells due to its non-specific effects on oxidative metabolism and cellular redox.
Abstract: Etomoxir (ETO) is a widely used small-molecule inhibitor of fatty acid oxidation (FAO) through its irreversible inhibitory effects on the carnitine palmitoyl-transferase 1a (CPT1a). We used this compound to evaluate the role of fatty acid oxidation in rapidly proliferating T cells following costimulation through the CD28 receptor. We show that ETO has a moderate effect on T cell proliferation with no observable effect on memory differentiation, but a marked effect on oxidative metabolism. We show that this oxidative metabolism is primarily dependent upon glutamine rather than FAO. Using an shRNA approach to reduce CPT1a in T cells, we further demonstrate that the inhibition of oxidative metabolism in T cells by ETO is independent of its effects on FAO at concentrations exceeding 5 μM. Concentrations of ETO above 5 μM induce acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells. In aggregate, these data indicate that ETO lacks specificity for CTP1a above 5 μM, and caution should be used when employing this compound for studies in cells due to its non-specific effects on oxidative metabolism and cellular redox.

103 citations

Patent
29 Jul 1998
TL;DR: In this article, a layer of Pd is formed on a first wafer and an adhesion layer of chromium (Cr) attaches the palladium layer to the second wafer, and the engaged wafers are annealed to form a palladium-silicide (PdSi) bond.
Abstract: Two wafers are bonded together through an annealing process that maintains temperatures at CMOS compatible levels (i.e., below 500 degrees Celsius). A layer of palladium (Pd) is formed on a first wafer. Preferably an adhesion layer of chromium (Cr) attaches the palladium layer to the first wafer. The palladium layer is engaged with silicon (Si) from a second wafer, and the engaged wafers are annealed to form a palladium-silicide (PdSi) bond between the palladium layer of the first wafer and the silicon of the second wafer. In addition to bonding the first wafer to the second wafer, the palladium-silicon bond may be used to form an electrical connection between the two wafers so that circuits on both wafers may communicate to one another through the palladium-silicon bond.

102 citations


Authors

Showing all 7402 results

NameH-indexPapersCitations
Hongjie Dai197570182579
Zhuang Liu14953587662
Jie Liu131153168891
Thomas Quertermous10340552437
John E. Bowers102176749290
Roy G. Gordon8944931058
Masaru Tomita7667740415
Stuart Lindsay7434722224
Ron Shamir7431923670
W. Richard McCombie7114464155
Tomoyoshi Soga7139221209
Michael R. Krames6532118448
Shabaz Mohammed6418817254
Geert Leus6260919492
Giuseppe Gigli6154115159
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
20228
2021142
2020157
2019168
2018164