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Institution

Aix-Marseille University

EducationMarseille, France
About: Aix-Marseille University is a education organization based out in Marseille, France. It is known for research contribution in the topics: Population & Galaxy. The organization has 24326 authors who have published 54240 publications receiving 1455416 citations. The organization is also known as: University Aix-Marseille & université d'Aix-Marseille.


Papers
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Journal ArticleDOI
T. Aoyama1, Nils Asmussen2, M. Benayoun3, Johan Bijnens4  +146 moreInstitutions (64)
TL;DR: The current status of the Standard Model calculation of the anomalous magnetic moment of the muon has been reviewed in this paper, where the authors present a detailed account of recent efforts to improve the calculation of these two contributions with either a data-driven, dispersive approach, or a first-principle, lattice-QCD approach.
Abstract: We review the present status of the Standard Model calculation of the anomalous magnetic moment of the muon. This is performed in a perturbative expansion in the fine-structure constant $\alpha$ and is broken down into pure QED, electroweak, and hadronic contributions. The pure QED contribution is by far the largest and has been evaluated up to and including $\mathcal{O}(\alpha^5)$ with negligible numerical uncertainty. The electroweak contribution is suppressed by $(m_\mu/M_W)^2$ and only shows up at the level of the seventh significant digit. It has been evaluated up to two loops and is known to better than one percent. Hadronic contributions are the most difficult to calculate and are responsible for almost all of the theoretical uncertainty. The leading hadronic contribution appears at $\mathcal{O}(\alpha^2)$ and is due to hadronic vacuum polarization, whereas at $\mathcal{O}(\alpha^3)$ the hadronic light-by-light scattering contribution appears. Given the low characteristic scale of this observable, these contributions have to be calculated with nonperturbative methods, in particular, dispersion relations and the lattice approach to QCD. The largest part of this review is dedicated to a detailed account of recent efforts to improve the calculation of these two contributions with either a data-driven, dispersive approach, or a first-principle, lattice-QCD approach. The final result reads $a_\mu^\text{SM}=116\,591\,810(43)\times 10^{-11}$ and is smaller than the Brookhaven measurement by 3.7$\sigma$. The experimental uncertainty will soon be reduced by up to a factor four by the new experiment currently running at Fermilab, and also by the future J-PARC experiment. This and the prospects to further reduce the theoretical uncertainty in the near future-which are also discussed here-make this quantity one of the most promising places to look for evidence of new physics.

420 citations

Book ChapterDOI
TL;DR: This tutorial chapter is intended to give an "hands on" view of FCS, including calibration, measurement, and data treatment, and the major difficulties that are encountered when performing for the first time FCS.
Abstract: Fluorescence correlation spectroscopy (FCS), implemented in microscopy, relies on performing an autocorrelation of the time fluctuating intensity arising from individual molecules diffusing through a confocal volume. It allows us to investigate a large variety of dynamic processes and to quantify photophysical, photochemical, interaction, diffusion, and transport properties of molecules. This tutorial chapter is intended to give an "hands on" view of FCS. After a brief introduction on the principle of FCS, the major theoretical assumptions are emphasized, and the main analytical expression are given. Then the key parameters that have to be considered when building a FCS system are discussed. The complete method of operation is described, including calibration, measurement, and data treatment. The major difficulties that are encountered when performing for the first time FCS are illustrated by examples of measurements, and possible solutions are proposed.

418 citations

Journal ArticleDOI
V. M. Abazov1, Brad Abbott2, M. Abolins3, Bobby Samir Acharya4  +601 moreInstitutions (73)
TL;DR: In this article, the authors reported the observation of the X(3872) in the J/psipi(+)pi(-) channel with decaying to mu(+)mu(-), in p (p) over bar collisions at roots=1.96 TeV.
Abstract: We report the observation of the X(3872) in the J/psipi(+)pi(-) channel, with J/psi decaying to mu(+)mu(-), in p (p) over bar collisions at roots=1.96 TeV. Using approximately 230 pb(-1) of data collected with the Run II D0 detector, we observe 522+/-100 X(3872) candidates. The mass difference between the X(3872) state and the J/psi is measured to be 774.9+/-3.1(stat)+/-3.0(syst) MeV/c(2). We have investigated the production and decay characteristics of the X(3872) and find them to be similar to those of the psi(2S) state.

418 citations

Journal ArticleDOI
TL;DR: The method described is reproducible and provides an assessment of the global amount of LV trabeculation and is highly sensitive and specific for the diagnosis of LVNC.
Abstract: Aims To describe a method for measuring trabeculated left ventricular (LV) mass using cardiac magnetic resonance imaging and to assess its value in the diagnosis of left ventricular non-compaction (LVNC). Methods and results Between January 2003 and 2008, we prospectively included 16 patients with LVNC. During the mean period, we included 16 patients with dilated cardiomyopathy (DCM), 16 patients with hypertrophic cardiomyopathy (HCM), and 16 control subjects. Left ventricular volumes, LV ejection fraction, and trabeculated LV mass were measured in the four different populations. The percentage of trabeculated LV mass was almost three times higher in the patients with LVNC (32 ± 10%), compared with those with DCM (11 ± 4%, P < 0.0001), HCM (12 ± 4%, P < 0.0001), and controls (12 ± 5%, P < 0.0001). A value of trabeculated LV mass above 20% of the global mass of the LV predicted the diagnosis of LVNC with a sensitivity of 93.7% [95% confidence interval (CI), 71.6–98.8%] and a specificity of 93.7% (95% CI, 83.1–97.8%; κ = 0.84). Conclusion The method described is reproducible and provides an assessment of the global amount of LV trabeculation. A trabeculated LV mass above 20% of the global LV mass is highly sensitive and specific for the diagnosis of LVNC.

417 citations

Journal ArticleDOI
Fergus J. Couch1, Xianshu Wang1, Lesley McGuffog2, Andy C. H. Lee2  +258 moreInstitutions (100)
TL;DR: It is estimated that the breast cancer lifetime risks for the5% of BRCA1 carriers at lowest risk are 28%–50% compared to 81%–100% for the 5% at highest risk, and the ovarian cancer lifetime risk is 63% or higher, based on the known cancer risk-modifying loci.
Abstract: BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7 x 10(-8), HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4 x 10(-8), HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4 x 10(-8), HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific association. The 17q21.31 locus was also associated with ovarian cancer risk in 8,211 BRCA2 carriers (P = 2 x 10(-4)). These loci may lead to an improved understanding of the etiology of breast and ovarian tumors in BRCA1 carriers. Based on the joint distribution of the known BRCA1 breast cancer risk-modifying loci, we estimated that the breast cancer lifetime risks for the 5% of BRCA1 carriers at lowest risk are 28%-50% compared to 81%-100% for the 5% at highest risk. Similarly, based on the known ovarian cancer risk-modifying loci, the 5% of BRCA1 carriers at lowest risk have an estimated lifetime risk of developing ovarian cancer of 28% or lower, whereas the 5% at highest risk will have a risk of 63% or higher. Such differences in risk may have important implications for risk prediction and clinical management for BRCA1 carriers.

417 citations


Authors

Showing all 24784 results

NameH-indexPapersCitations
Didier Raoult1733267153016
Andrea Bocci1722402176461
Marc Humbert1491184100577
Carlo Rovelli1461502103550
Marc Besancon1431799106869
Jian Yang1421818111166
Josh Moss139101989255
Maksym Titov1391573128335
Bernard Henrissat139593100002
R. D. Kass1381920107907
Stylianos E. Antonarakis13874693605
Jean-Paul Kneib13880589287
Brad Abbott137156698604
Shu Li136100178390
Georges Aad135112188811
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023170
2022748
20215,607
20205,697
20195,288
20185,125