Showing papers by "Albion College published in 1980"

Effects of cytochalasins on Neurospora crassa

Abstract: Growth of various strains ofNeurospora crassa in the continued presence of cytochalasins A and B results in the following pattern. At low concentration the drugs cause an increase in branching which, depending on the strain, may also reveal an increase in dry weight. Increasing the concentration results in abnormal hyphae (swollen, irregular) and eventually in inhibition of growth. Most strains are inhibited at 10–20 Μg/ml cytochalasin A. Ultrastructure of hyphae grown in the presence of cytochalasin A reveals the presence of abnormal wall deposits. These deposits are not observed in cultures grown with cytochalasin B which generally causes a lower growth response also.

LABSIM: A data-driven simulation program for instruction in research design and statistics

Abstract: LABSIM is a general-purpose FORTRAN program that simulates the collection of data from laboratory experiments. Student-specified parameters are employed in a multiple-regression model that allows manipulation or control of up to 10 potential independent variables. Variables may be discrete (up to eight levels), continuous, or range (e.g., IQ). Raw scores may be generated for up to six groups, optionally accompanied by statistical analyses for simple between- or within-subjects designs or for factorial designs, including mixed factorial designs. Seventeen models (content areas) are currently available. As contrasted with other simulation programs, LABSIM models are exceptionally easy to design and implement; no computer expertise is required. Summary data automatically collected by LABSIM indicate a high success rate and extensive use of the program beyond course requirements. The current version of LABSIM is available in either batch or interactive form. A newer version that allows the simultaneous manipulation of up to three independent variables will be available soon.