Albion College

About: Albion College is a education organization based out in Albion, Michigan, United States. It is known for research contribution in the topics: Population & Higher education. The organization has 485 authors who have published 754 publications receiving 20907 citations.

A Genetic Suppressor of Two Dominant Temperature-Sensitive Lethal Proteasome Mutants of Drosophila melanogaster Is Itself a Mutated Proteasome Subunit Gene

Abstract: Two dominant temperature-sensitive (DTS) lethal mutants of Drosophila melanogaster are Pros261 and Prosβ21, previously known as DTS5 and DTS7. Heterozygotes for either mutant die as pupae when raised at 29°, but are normally viable and fertile at 25°. Previous studies have identified these as missense mutations in the genes encoding the β6 and β2 subunits of the 20S proteasome, respectively. In an effort to isolate additional proteasome-related mutants a screen for dominant suppressors of Pros261 was carried out, resulting in the identification of Pros25SuDTS [originally called Su(DTS)], a missense mutation in the gene encoding the 20S proteasome α2 subunit. Pros25SuDTS acts in a dominant manner to rescue both Pros261 and Prosβ21 from their DTS lethal phenotypes. Using an in vivo protein degradation assay it was shown that this suppression occurs by counteracting the dominant-negative effect of the DTS mutant on proteasome activity. Pros25SuDTS is a recessive polyphasic lethal at ambient temperatures. The effects of these mutants on larval neuroblast mitosis were also examined. While Prosβ21 shows a modest increase in the number of defective mitotic figures, there were no defects seen with the other two mutants, other than slightly reduced mitotic indexes.

Junk food consumption and screen time: association with childhood adiposity.

Abstract: Objectives: To determine the joint as- sociation of junk food consumption (JFC) and screen time (ST) with adiposity in children. Methods: Two hundred four- teen (121 girls, 93 boys) third-to-fifth- grade students (54% Hispanic, 35% Af- rican American, 8% white) completed a lifestyle behavior survey, which included self-reported JFC and ST, as part of a school-based lifestyle intervention pro- gram. Results: Neither JFC nor ST, inde- pendently or jointly, was associated with adiposity measures. JFC and ST were sig- nificantly correlated (r = .375). Conclu- sions: The low achievement of physical activity and screen time recommenda- tions and high prevalence of overweight/ obesity in this mostly minority, low so- cioeconomic status population indicates a potential focus for intervention.

The effects of anxiety on motor-steadiness in competitive and noncompetitive conditions

Abstract: Twenty HA and 20 LA Ss were selected from 101 males who had taken the MAS. The Ss were further divided into competitive and noncompetitive subgroups and administered a simple motor steadiness test. It was found that LA Ss made fewer errors than HA Ss in the steadiness test and that com­ petition exacerbated performance differences between HA and LA Ss. Over the years, a number of scales have been developed for the purpose of measuring "manifest" anxiety. Of these scales, Taylor's (1953) MAS seems to have generated the most controversy. Much of the ensuing controversy has to do with whether or not the MAS measures a constant "level of internal anxiety or emotionality," or whether it measures susceptibility to "anxiety" provoking stimuli. In either case, it should follow that people with high MA scores would differ from low scorers in a variety of performance measures. The literature, however, does not support this contention; rather, such relationships have been less than conclusive.

The influence of oral recall on immediate and delayed memory for meaningful material practiced under delayed auditory feedback.

Abstract: Summary Three groups of Ss read a five-paragraph story. One group read the middle paragraph under conditions of .2-second DAF. The other two groups functioned as control groups. Both an immediate and a delayed oral recall were obtained. The usual changes in reading rate were observed. Immediate memory for the material presented under DAF was severely impaired. Delayed retention showed a marked relative increase, but not enough of an absolute increase to eliminate the significant difference between the experimental and the control groups.