Institution
Aligarh Muslim University
Education•Aligarh, Uttar Pradesh, India•
About: Aligarh Muslim University is a education organization based out in Aligarh, Uttar Pradesh, India. It is known for research contribution in the topics: Population & Adsorption. The organization has 8218 authors who have published 16416 publications receiving 289068 citations. The organization is also known as: AMU.
Topics: Population, Adsorption, Metal ions in aqueous solution, Aqueous solution, Circular dichroism
Papers published on a yearly basis
Papers
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TL;DR: In this article, a review on the synthesis method of graphene and application of graphene oxide-based nanomaterials in the term of heavy metal removal from wastewater is presented, where the advantages, drawbacks, comparison of the data efficiencies, and research requirements are further highlighted, elaborated and discussed detailly.
297 citations
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TL;DR: The results indicated that film diffusion was a major mode of adsorption and the breakthrough capacities were found to be 84.03, 163.9 and 188.6 mg/g at 30, 40 and 50 degrees C.
294 citations
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TL;DR: Underlying mechanism(s) of apoptosis due to CuO NPs exposure should be further invested at in vivo level and decrease in mitochondrial membrane potential with a concomitant increase in the gene expression of bax/bcl2 ratio suggested that mitochondria mediated pathway involved in CuONPs induced apoptosis.
Abstract: Copper oxide nanoparticles (CuO NPs) are heavily utilized in semiconductor devices, gas sensor, batteries, solar energy converter, microelectronics and heat transfer fluids. It has been reported that liver is one of the target organs for nanoparticles after they gain entry into the body through any of the possible routes. Recent studies have shown cytotoxic response of CuO NPs in liver cells. However, the underlying mechanism of apoptosis in liver cells due to CuO NPs exposure is largely lacking. We explored the possible mechanisms of apoptosis induced by CuO NPs in human hepatocellular carcinoma HepG2 cells. Prepared CuO NPs were spherical in shape with a smooth surface and had an average diameter of 22 nm. CuO NPs (concentration range 2–50 µg/ml) were found to induce cytotoxicity in HepG2 cells in dose-dependent manner, which was likely to be mediated through reactive oxygen species generation and oxidative stress. Tumor suppressor gene p53 and apoptotic gene caspase-3 were up-regulated due to CuO NPs exposure. Decrease in mitochondrial membrane potential with a concomitant increase in the gene expression of bax/bcl2 ratio suggested that mitochondria mediated pathway involved in CuO NPs induced apoptosis. This study has provided valuable insights into the possible mechanism of apoptosis caused by CuO NPs at in vitro level. Underlying mechanism(s) of apoptosis due to CuO NPs exposure should be further invested at in vivo level.
291 citations
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TL;DR: The effector functions of pro- and anti-inflammatory cytokines and the role of cytokine gene polymorphism in the pathogenesis of RA are described.
290 citations
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TL;DR: This review aims to highlight current overview on the binding strategies of protein to various ligands that may be expected to lead to significant clinical applications.
290 citations
Authors
Showing all 8370 results
Name | H-index | Papers | Citations |
---|---|---|---|
Sandeep Kumar | 94 | 1563 | 38652 |
Detlef W. Bahnemann | 88 | 517 | 48826 |
Gaurav Sharma | 82 | 1244 | 31482 |
Sang Un Ahn | 82 | 391 | 22067 |
M. Irfan | 80 | 241 | 20154 |
M. Mohisin Khan | 77 | 266 | 17940 |
Nazeer Ahmad | 74 | 143 | 18305 |
Rajeev Kumar | 72 | 296 | 20848 |
Syed F. Ali | 71 | 446 | 18669 |
Ahmad Umar | 71 | 740 | 21014 |
Aamir Ahmad | 63 | 251 | 13404 |
Mohammad Athar | 63 | 329 | 14384 |
A. Ahmad Masoodi | 62 | 80 | 12771 |
Shahid Husain | 62 | 437 | 14444 |
Mohd Danish Azmi | 61 | 186 | 13130 |