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Institution

Alion Science and Technology

CompanyMcLean, Virginia, United States
About: Alion Science and Technology is a company organization based out in McLean, Virginia, United States. It is known for research contribution in the topics: Poison control & Task (project management). The organization has 271 authors who have published 405 publications receiving 12424 citations.


Papers
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Journal ArticleDOI
TL;DR: The microscopic studies demonstrated that nanoparticle-exposed cells at higher doses became abnormal in size, displaying cellular shrinkage, and an acquisition of an irregular shape, which suggested that cytotoxicity of Ag (15, 100 nm) in liver cells is likely to be mediated through oxidative stress.

1,949 citations

Journal ArticleDOI
TL;DR: Sulfate esters are found to account for a larger fraction of the SOA mass when the acidity of seed aerosol is increased, a result consistent with aerosol acidity increasing SOA formation.
Abstract: Recent work has shown that particle-phase reactions contribute to the formation of secondary organic aerosol (SOA), with enhancements of SOA yields in the presence of acidic seed aerosol. In this study, the chemical composition of SOA from the photooxidations of α-pinene and isoprene, in the presence or absence of sulfate seed aerosol, is investigated through a series of controlled chamber experiments in two separate laboratories. By using electrospray ionization−mass spectrometry, sulfate esters in SOA produced in laboratory photooxidation experiments are identified for the first time. Sulfate esters are found to account for a larger fraction of the SOA mass when the acidity of seed aerosol is increased, a result consistent with aerosol acidity increasing SOA formation. Many of the isoprene and α-pinene sulfate esters identified in these chamber experiments are also found in ambient aerosol collected at several locations in the southeastern U.S. It is likely that this pathway is important for other bioge...

566 citations

Journal ArticleDOI
TL;DR: It is concluded that SA, mental workload, and trust are viable constructs that are valuable in understanding and predicting human-system performance in complex systems.
Abstract: Cognitive engineering needs viable constructs and principles to promote better understanding and prediction of human performance in complex systems. Three human cognition and performance constructs that have been the subjects of much attention in research and practice over the past three decades are situation awareness (SA), mental workload, and trust in automation. Recently, Dekker and Woods (2002) and Dekker and Hollnagel (2004; henceforth DWH) argued that these constructs represent "folk models" without strong empirical foundations and lacking scientific status. We counter this view by presenting a brief description of the large science base of empirical studies on these constructs. We show that the constructs can be operationalized using behavioral, physiological, and subjective measures, supplemented by computational modeling, but that the constructs are also distinct from human performance. DWH also caricatured as "abracadabra" a framework suggested by us to address the problem of the design of automated systems (Parasuraman, Sheridan, & Wickens, 2000). We point to several factual and conceptual errors in their description of our approach. Finally, we rebut DWH's view that SA, mental workload, and trust represent folk concepts that are not falsifiable. We conclude that SA, mental workload, and trust are viable constructs that are valuable in understanding and predicting human-system performance in complex systems.

527 citations

Journal ArticleDOI
TL;DR: In this paper, an organic tracer-based method containing laboratory and field study components was used to estimate the secondary organic aerosol (SOA) contributions of biogenic and anthropogenic hydrocarbons to ambient organic carbon (OC) concentrations in PM2.5 during 2003 in Research Triangle Park, NC.

430 citations

Journal ArticleDOI
TL;DR: Empirical studies of human-automation interaction and their implications for automation design suggest adaptive automation can provide additional benefits in balancing workload and maintaining the user's situation awareness, although more research is required to identify when adaptation should be user controlled or system driven.
Abstract: OBJECTIVE: The authors discuss empirical studies of human-automation interaction and their implications for automation design. BACKGROUND: Automation is prevalent in safety-critical systems and increasingly in everyday life. Many studies of human performance in automated systems have been conducted over the past 30 years. METHODS: Developments in three areas are examined: levels and stages of automation, reliance on and compliance with automation, and adaptive automation. RESULTS: Automation applied to information analysis or decision-making functions leads to differential system performance benefits and costs that must be considered in choosing appropriate levels and stages of automation. Human user dependence on automated alerts and advisories reflects two components of operator trust, reliance and compliance, which are in turn determined by the threshold designers use to balance automation misses and false alarms. Finally, adaptive automation can provide additional benefits in balancing workload and maintaining the user's situation awareness, although more research is required to identify when adaptation should be user controlled or system driven. CONCLUSIONS: The past three decades of empirical research on humans and automation has provided a strong science base that can be used to guide the design of automated systems. APPLICATION: This research can be applied to most current and future automated systems. Language: en

396 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20214
20206
20193
20186
201718
201617