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Institution

Amazon.com

CompanySeattle, Washington, United States
About: Amazon.com is a company organization based out in Seattle, Washington, United States. It is known for research contribution in the topics: Service (business) & Service provider. The organization has 13363 authors who have published 17317 publications receiving 266589 citations.


Papers
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Journal ArticleDOI
17 Nov 2020
TL;DR: In this paper, the convergence of the natural gradient optimizer for the variational quantum eigensolver across multiple spin chain systems was shown for a single spin chain system, where the optimizer is based on the natural gradients.
Abstract: This paper shows the convergence of the natural gradient optimizer for the variational quantum eigensolver across multiple spin chain systems.

104 citations

Journal ArticleDOI
TL;DR: The goal of this work is to understand the underlying reason why PCA is effective for modeling lung motion and find the optimal number of PCA coefficients for accurate lung motion modeling and propose a new method to derive the entire lung motion using a single internal marker based on the PCA model.
Abstract: Respiration-induced organ motion is one of the major uncertainties in lung cancer radiotherapy and is crucial to be able to accurately model the lung motion. Most work so far has focused on the study of the motion of a single point (usually the tumor center of mass), and much less work has been done to model the motion of the entire lung. Inspired by the work of Zhang et al (2007 Med. Phys. 34 4772–81), we believe that the spatiotemporal relationship of the entire lung motion can be accurately modeled based on principle component analysis (PCA) and then a sparse subset of the entire lung, such as an implanted marker, can be used to drive the motion of the entire lung (including the tumor). The goal of this work is twofold. First, we aim to understand the underlying reason why PCA is effective for modeling lung motion and find the optimal number of PCA coefficients for accurate lung motion modeling. We attempt to address the above important problems both in a theoretical framework and in the context of real clinical data. Second, we propose a new method to derive the entire lung motion using a single internal marker based on the PCA model. The main results of this work are as follows. We derived an important property which reveals the implicit regularization imposed by the PCA model. We then studied the model using two mathematical respiratory phantoms and 11 clinical 4DCT scans for eight lung cancer patients. For the mathematical phantoms with cosine and an even power (2n) of cosine motion, we proved that 2 and 2n PCA coefficients and eigenvectors will completely represent the lung motion, respectively. Moreover, for the cosine phantom, we derived the equivalence conditions for the PCA motion model and the physiological 5D lung motion model (Low et al 2005 Int. J. Radiat. Oncol. Biol. Phys. 63 921–9). For the clinical 4DCT data, we demonstrated the modeling power and generalization performance of the PCA model. The average 3D modeling error using PCA was within 1 mm (0.7 ± 0.1 mm). When a single artificial internal marker was used to derive the lung motion, the average 3D error was found to be within 2 mm (1.8 ± 0.3 mm) through comprehensive statistical analysis. The optimal number of PCA coefficients needs to be determined on a patient-by-patient basis and two PCA coefficients seem to be sufficient for accurate modeling of the lung motion for most patients. In conclusion, we have presented thorough theoretical analysis and clinical validation of the PCA lung motion model. The feasibility of deriving the entire lung motion using a single marker has also been demonstrated on clinical data using a simulation approach.

104 citations

Patent
31 Mar 2006
TL;DR: In this paper, the authors describe techniques that facilitate generating useful content based on user interactions, such as by providing an answer-providing service that facilitates interactions between users who supply questions and users who provide responses to the questions of other users, as well as using the generated content in various ways.
Abstract: Techniques are described that facilitate generating useful content based on user interactions, such as by providing an answer-providing service that facilitates interactions between users who supply questions and users who supply responses to the questions of other users, as well as using the generated content in various ways. In some situations, some users of the answer-providing service are provided with pay-per-response functionality in which the user is allowed to elect on a per-question basis to include a paid response or other indicated information (e.g., advertisements) in an answer for a question in exchange for payment from the user, such as for use by merchants with questions that are related to products and/or services provided by the merchants.

104 citations

Proceedings ArticleDOI
01 Oct 2019
TL;DR: AutoFocus as discussed by the authors predicts category agnostic segmentation maps for small objects at coarser scales, called FocusPixels, which can be predicted with high recall, and in many cases, they only cover a small fraction of the entire image.
Abstract: This paper describes AutoFocus, an efficient multi-scale inference algorithm for deep-learning based object detectors. Instead of processing an entire image pyramid, AutoFocus adopts a coarse to fine approach and only processes regions which are likely to contain small objects at finer scales. This is achieved by predicting category agnostic segmentation maps for small objects at coarser scales, called FocusPixels. FocusPixels can be predicted with high recall, and in many cases, they only cover a small fraction of the entire image. To make efficient use of FocusPixels, an algorithm is proposed which generates compact rectangular FocusChips which enclose FocusPixels. The detector is only applied inside FocusChips, which reduces computation while processing finer scales. Different types of error can arise when detections from FocusChips of multiple scales are combined, hence techniques to correct them are proposed. AutoFocus obtains an mAP of 47.9% (68.3% at 50% overlap) on the COCO test-dev set while processing 6.4 images per second on a Titan X (Pascal) GPU. This is 2.5X faster than our multi-scale baseline detector and matches its mAP. The number of pixels processed in the pyramid can be reduced by 5X with a 1% drop in mAP. AutoFocus obtains more than 10% mAP gain compared to RetinaNet but runs at the same speed with the same ResNet-101 backbone.

103 citations

Patent
20 Nov 2000
TL;DR: In this paper, a facility for notifying a first user about a purchase made by a second user is described, where the facility detects that the second user has purchased an item.
Abstract: A facility for notifying a first user about a purchase made by a second user is described. The facility detects that the second user has purchased an item. The facility further determines that the first user has a purchase notification relationship with the second user. The facility then provides to the first user a notification that the second user has purchased the item.

103 citations


Authors

Showing all 13498 results

NameH-indexPapersCitations
Jiawei Han1681233143427
Bernhard Schölkopf1481092149492
Christos Faloutsos12778977746
Alexander J. Smola122434110222
Rama Chellappa120103162865
William F. Laurance11847056464
Andrew McCallum11347278240
Michael J. Black11242951810
David Heckerman10948362668
Larry S. Davis10769349714
Chris M. Wood10279543076
Pietro Perona10241494870
Guido W. Imbens9735264430
W. Bruce Croft9742639918
Chunhua Shen9368137468
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20234
2022168
20212,015
20202,596
20192,002
20181,189