Showing papers by "American Cancer Society published in 1970"

Histologic changes in the larynx in relation to smoking habits.

Abstract: Histologic changes in the larynx were microscopically studied in 942 men who died and came to autopsy at the Veterans Administration Hospital, East Orange, N. J., between 1964-1967. Atypical changes in cells in the epithelium of the larynx were most often observed in the true vocal cord and, to a lesser degree, in the false vocal cord and the area of the larynx above the vocal cord. The least changes were observed in the area below the vocal cord. The histologic changes (including cells with atypical nuclei, carcinoma in situ, and early invasive carcinoma) were highly related to smoking habits. They were much higher in cigarette smokers than in men who never smoked; they increased in proportion to the number of cigarettes smoked per day before death and were seen to a greater degree in cigarette smokers than in cigar and pipe smokers. Ex-cigarette smokers had fewer such changes than men who continued to smoke cigarettes up to the time of death. Cells with disintegrating nuclei were found mainly in ex-cigarette smokers.

Incidence of cutaneous cancer in Minnesota

Abstract: In a survey conducted in Minnesota, a special effort was made to record cases of cutaneous cancer encountered in 1963 by dermatologists, radiotherapists, and pathologists. The latter group probably includes almost all of the patients treated by surgeons in hospitals and the great majority of those treated by surgeons in their offices. In an earlier sample study, we found this to be true of general practitioners. A total of 2,358 Minnesotans was identified as having cutaneous cancer, presenting first during 1963. This exceeded the most plausible estimates based on previously available data. The annual incidence rates recorded were 71.5 per 100,000 men and 47.2 per 100,000 women. These rates place cutaneous cancer clearly in front among types of cancer in Minnesota, although it is a northern state whose population has relatively low actinic exposure.

Carcinoids of the large intestine.

Abstract: Twenty-two cases of carcinoid of the large intestine are presented. The pathology, clinical presentation and long-term results are reviewed. Eight of the 22 patients had evidence of nodal or distant spread and eight patients are known to have died of the disease, seven of the eight within five years of surgical operation. Criteria for malignancy are discussed and therapy based on these factors is considered. The most favorable results occurred in those who had wide excision of the tumor and node resection. There were no cases of carcinoid syndrome in the group.

American Cancer Society plans for a long-range study of colonic and rectal cancer.

Abstract: ORDINARILY, the pu rpose of p resen t ing a p a p e r at a scientific mee t ing is to i m p a r t i n f o r m a t i o n or new ideas to the a t t d i e n c e to tel l them some th ing tha t they do no t a l r eady know. T h i s is an u n u s u a l si tuation. T h e r e is n o t h i n g i cou ld say a b o u t cancer of the colon and r e c t u m tha t you do not know; whi le you know a grea t dea l a b o u t the disease tha t I do no t know. I am here to seek r a the r than to give advice and suggestions. Cancer of the colon and r ec tum may be the most i m p o r t a n t cancer in the U n i t e d States today. In inc idence it is second on ly to skin cancer ; as a cause of dea th i t is second only to h m g cancer. I t is e s t ima ted tha t in 1968 a b o u t 105,000 A m e r i c a n men and women deve loped skin cancer, a b o u t 73,000 deve loped colorecta l cancer, and a b o u t 63,000 deve loped lung cancer. However, the grea t m a j o r i t y of skin cancers are cured, many colorecta l cancers are cured, and few h m g cancers are cured. In 1968, only a b o u t 5,000 men and w o m e n d ied of skin cancer, 45,000 d ied of co lorec ta l cancer, a n d 57,000 d ied of lung cancer. Because of the obvious i m p o r t a n c e of the subject , the Med ica l and Scientif ic Executive C o m m i t t e e of the A m e r i c a n Cancer Society in 1968 reques ted me to p r e p a r e p lans for extensive research in the ep idemi otogy and e t io logy of colorecta l cancer. 3 was wi l l ing to u n d e r t a k e the ass ignment . ~Iowever, at the outse t Z wished to make i t c lear tha t qu ick :~esults could no t be ex-