Amirkabir University of Technology

About: Amirkabir University of Technology is a education organization based out in Tehran, Iran. It is known for research contribution in the topics: Nonlinear system & Finite element method. The organization has 15254 authors who have published 31165 publications receiving 487551 citations. The organization is also known as: Tehran Polytechnic & Tehran Polytechnic University.

Droplet microfluidics: fundamentals and its advanced applications

Abstract: Droplet-based microfluidic systems have been shown to be compatible with many chemical and biological reagents and capable of performing a variety of operations that can be rendered programmable and reconfigurable. This platform has dimensional scaling benefits that have enabled controlled and rapid mixing of fluids in the droplet reactors, resulting in decreased reaction times. This, coupled with the precise generation and repeatability of droplet operations, has made the droplet-based microfluidic system a potent high throughput platform for biomedical research and applications. In addition to being used as micro-reactors ranging from the nano- to femtoliter (10−15 liters) range; droplet-based systems have also been used to directly synthesize particles and encapsulate many biological entities for biomedicine and biotechnology applications. For this, in the following article we will focus on the various droplet operations, as well as the numerous applications of the system and its future in many advanced scientific fields. Due to advantages of droplet-based systems, this technology has the potential to offer solutions to today's biomedical engineering challenges for advanced diagnostics and therapeutics.