Institution
Amity University
Education•Noida, India•
About: Amity University is a education organization based out in Noida, India. It is known for research contribution in the topics: Population & Cloud computing. The organization has 7827 authors who have published 12742 publications receiving 86037 citations.
Topics: Population, Cloud computing, Software, The Internet, Big data
Papers published on a yearly basis
Papers
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TL;DR: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates, and there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries.
5,802 citations
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Christopher J L Murray1, Christopher J L Murray2, Christopher J L Murray3, Aleksandr Y. Aravkin1 +2269 more•Institutions (286)
TL;DR: The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure.
3,059 citations
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TL;DR: Antioxidant defenses against ROS in microbial cells and the use of ROS by antimicrobial host defense systems are covered and reactive nitrogen species and related therapeutics, such as acidified nitrite and nitric oxide-releasing nanoparticles are covered.
Abstract: Reactive oxygen species (ROS) can attack a diverse range of targets to exert antimicrobial activity, which accounts for their versatility in mediating host defense against a broad range of pathogens. Most ROS are formed by the partial reduction in molecular oxygen. Four major ROS are recognized comprising superoxide (O2•-), hydrogen peroxide (H2O2), hydroxyl radical (•OH), and singlet oxygen ((1)O2), but they display very different kinetics and levels of activity. The effects of O2•- and H2O2 are less acute than those of •OH and (1)O2, because the former are much less reactive and can be detoxified by endogenous antioxidants (both enzymatic and nonenzymatic) that are induced by oxidative stress. In contrast, no enzyme can detoxify •OH or (1)O2, making them extremely toxic and acutely lethal. The present review will highlight the various methods of ROS formation and their mechanism of action. Antioxidant defenses against ROS in microbial cells and the use of ROS by antimicrobial host defense systems are covered. Antimicrobial approaches primarily utilizing ROS comprise both bactericidal antibiotics and nonpharmacological methods such as photodynamic therapy, titanium dioxide photocatalysis, cold plasma, and medicinal honey. A brief final section covers reactive nitrogen species and related therapeutics, such as acidified nitrite and nitric oxide-releasing nanoparticles.
744 citations
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TL;DR: The importance and role of A BA signaling with regard to various stresses as well as regulation of ABA biosynthetic pathway along with the transcription factors for stress tolerance are enlightened.
Abstract: Abiotic stress is one of the severe stresses of environment that lowers the growth and yield of any crop even on irrigated land throughout the world. A major phytohormone abscisic acid (ABA) plays an essential part in acting towards varied range of stresses like heavy metal stress, drought, thermal or heat stress, high level of salinity, low temperature and radiation stresses. It also finds its role in various developmental processes including seed germination, seed dormancy, and closure of stomata. Abscisic acid acts by modifying the expression level of gene and subsequent analysis of cis- and trans-acting regulatory elements of responsive promoters. It also interacts with the signaling molecules of processes involved in retorting to stresses and development of seeds. On the whole, the stress to a plant can be susceptible or tolerant by taking into account the coordinated activities of various stress-responsive genes. Numbers of transcription factor are involved in regulating the expression of abscisic acid responsive genes by acting together with their respective cis‑acting elements. Hence, for improvement in stress-tolerance capacity of plants, it is necessary to understand the mechanism behind it. On this ground, this article enlightens the importance and role of ABA signaling with regard to various stresses as well as regulation of abscisic acid biosynthetic pathway along with the transcription factors for stress tolerance.
720 citations
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TL;DR: This work attempts to explore varying intricacies, excipients, manufacturing techniques and their underlying principles, production conditions, structural dynamics, prevalent destabilization mechanisms, and drug delivery applications of nanoemulsions to spike interest of those contemplating a foray in this field.
707 citations
Authors
Showing all 8136 results
Name | H-index | Papers | Citations |
---|---|---|---|
Ashok Kumar | 151 | 5654 | 164086 |
Rajendra Prasad | 86 | 945 | 29526 |
Gaurav Sharma | 82 | 1244 | 31482 |
Ashish Sharma | 75 | 909 | 20460 |
Sanjay Singh | 71 | 1133 | 22099 |
Narendra Tuteja | 68 | 354 | 27042 |
Ashwani Kumar | 66 | 703 | 18099 |
Manoj Kumar | 65 | 408 | 16838 |
Manish Kumar | 61 | 1425 | 21762 |
Rakesh Sharma | 60 | 673 | 14157 |
Ajit Varma | 57 | 432 | 12584 |
Rudra Deo Tripathi | 57 | 138 | 9640 |
Bhudev C. Das | 48 | 229 | 7144 |
D.K. Avasthi | 46 | 490 | 9120 |
Dattatray J. Late | 46 | 205 | 11647 |