Annamalai University

About: Annamalai University is a education organization based out in Chidambaram, Tamil Nadu, India. It is known for research contribution in the topics: Lipid peroxidation & Antioxidant. The organization has 8098 authors who have published 10758 publications receiving 203872 citations.

Effect of welding processes on tensile properties of AA6061 aluminium alloy joints

Abstract: The present investigation is aimed at to study the effect of welding processes such as GTAW, GMAW and FSW on mechanical properties of AA6061 aluminium alloy. The preferred welding processes of these alloys are frequently gas tungsten arc welding (GTAW) and gas metal arc welding (GMAW) due to their comparatively easier applicability and better economy. In this alloy, the weld fusion zones typically exhibit coarse columnar grains because of the prevailing thermal conditions during weld metal solidification. This often causes inferior weld mechanical properties and poor resistance to hot cracking. Friction stir welding (FSW) is a solid phase welding technique developed primarily for welding metals and alloys that heretofore had been difficult to weld using more traditional fusion techniques. Rolled plates of 6 mm thickness have been used as the base material for preparing single pass butt welded joints. The filler metal used for joining the plates is AA4043 (Al-5Si (wt%)) grade aluminium alloy. In the present work, tensile properties, micro hardness, microstructure and fracture surface morphology of the GMAW, GTAW and FSW joints have been evaluated, and the results are compared. From this investigation, it is found that FSW joints of AA6061 aluminium alloy showed superior mechanical properties compared with GTAW and GMAW joints, and this is mainly due to the formation of very fine, equiaxed microstructure in the weld zone.

Biosurfactant Producing Microbes and their Potential Applications: A Review

Abstract: Biosurfactants are surface-active biomolecules produced by microbes (bacteria, fungi, and yeast) and have several advantages over the chemical surfactants, such as lower toxicity, higher biodegradability, better environmental compatibility, higher foaming, high selectivity, and specific activity under extreme conditions such as temperature, pH, and salinity. Almost all the surfactants now available in the market are chemically synthesized. Recently, attention toward the biosurfactants was doubled, which is mainly due to their wide range of functional properties and the diverse synthetic capabilities of the microbes. Microbial biosurfactants are found to have a wide range of applications in environmental protection, which include enhancing oil recovery, controlling oil spills, biodegradation, and detoxification of oil-contaminated industrial effluents and soils. Biosurfactants produced by microorganisms have potential applications in pharmaceutical/medicine, food, cosmetic, pesticide, oil, and biodegradati...

Inhibitory effect of caffeic acid on cancer cell proliferation by oxidative mechanism in human HT-1080 fibrosarcoma cell line

Abstract: Caffeic acid (3,4-dihydroxy cinnamic acid) (CA) is naturally found in fruits, vegetables, olive oil, and coffee. This study was undertaken to evaluate the anticancer effect of caffeic acid on HT-1080 human fibrosarcoma cell line. The antiproliferative effect of caffeic acid was determined by MTT assay, and the oxidative stress was determined by lipid peroxidation, changes in the enzymatic, and non-enzymatic antioxidant status. To understand the mode of antiproliferative effect of CA, the authors observed intracellular ROS levels by DCFH-DA method, mitochondrial membrane potential alterations by Rh-123 staining, oxidative DNA damage by comet assay, and apoptotic morphological changes by AO/EtBr-staining method. The results show that caffeic acid enhances lipid peroxidative markers such as TBARS, CD, and LHP in HT-1080 cell line. Caffeic acid enhances the ROS levels, which is evidenced by the increased DCF fluorescence. Further, caffeic acid treatment altered the mitochondrial membrane potential in HT-1080 cells. Similarly, the authors observed increased oxidative DNA damage (% Tail DNA, % Tail length, Tail moment, and olive tail moment), and apoptotic morphological changes in caffeic acid-treated groups. These data suggest that caffeic acid exhibits potent anticancer effect in HT-1080 cell line, and that it may be used as an anticancer agent.