Annamalai University

About: Annamalai University is a education organization based out in Chidambaram, Tamil Nadu, India. It is known for research contribution in the topics: Lipid peroxidation & Antioxidant. The organization has 8098 authors who have published 10758 publications receiving 203872 citations.

The effect of Aegle marmelos fruit extract in streptozotocin diabetes: a histopathological study.

Abstract: Aegle marmelos Correa. (Bael) fruit exhibit antidiabetic, antihyperlipidaemic and antioxidant properties. This study was designed to elucidate the protective effect of an aqueous extract of Aegle marmelos fruits on the histopathology of the pancreas in streptozotocin-induced diabetic rats. Oral administration of Aegle marmelos fruit extract at doses of 125 and 250 mg/kg twice daily to diabetic rats for a period of 30 days resulted in a significant increase in body weight, weight of the pancreas and insulin levels associated with a significant decrease in fasting blood glucose levels. The fruit extract treated groups showed improved functional state of the pancreatic ss-cells and partially reversed the damage caused by streptozotocin to the pancreatic islets. The findings of our study indicate that Aegle marmelos fruit extract exhibits protective effects on the pancreas. The effects observed in the fruit extract treated animals were better those in animals treated with glibenclamide (300 microg/kg).

Identification of Vibrio campbellii isolated from diseased farm-shrimps from south India and establishment of its pathogenic potential in an Artemia model

Abstract: Shrimp diseases are frequently reported to be caused by closely related vibrios, and in many cases they are tentatively but inaccurately identified as Vibrio harveyi and related vibrios. In the present study, 28 biochemically identified V. harveyi-related strains isolated from diseased shrimps were randomly selected for further characterization by molecular tools. Twenty-six strains were identified as Vibrio campbellii and two as V. harveyi by sequence analysis of 16S rRNA and uridylate kinase genes. Haemolysin-gene-based species-specific multiplex PCR also confirmed these results. Experimental challenge studies using Artemia as a model showed that eight isolates were highly pathogenic, three were moderately pathogenic and the remaining 17 were non-pathogenic. Ribotyping with BglI clearly distinguished V. campbellii from V. harveyi, but it failed to separate pathogenic and non-pathogenic clusters. Artemia nauplii challenged with a fluorescently labelled highly pathogenic strain (IPEY54) showed patches in the digestive tract. However, no patches were observed for a non-pathogenic strain (IPEY41). Direct bacterial counts also supported colonization potential for the highly pathogenic strain. To our knowledge, this is the first report on the isolation and accurate identification of large numbers of V. campbellii associated with shrimp disease in aquacultural farms. V. campbellii has long been considered to be non-pathogenic and classified with V. harveyi-related bacteria. However, we show that this species may be an emerging aquaculture pathogen. This study will help to formulate suitable strategies to combat this newly identified pathogen.

Optimizing HVOF spray process parameters to attain minimum porosity and maximum hardness in WC–10Co–4Cr coatings

Abstract: Many thermal and thermo-chemical surface treatment techniques are being used to modify the surface of the material with desired properties for various applications in service. Nowadays, high velocity oxy-fuel (HVOF) spray is being widely used in industrial applications due to its ability to produce a high-quality coating with required hardness and low oxide content due to its high velocity impact inherent in the process. Porosity and hardness are two important coating properties for wear and corrosion related applications, and they play a significant role in the service life of the components. In HVOF spraying, the parameters such as oxygen flow rate, liquefied petroleum gas (LPG) flow rate, powder feed rate and spray distance have greater influence on the final properties of the coatings. The present work aims to select the optimum HVOF spray parameters to attain minimum porosity and maximum hardness in WC–10Co–4Cr coating sprayed on naval brass substrate material. Statistical tools such as design of experiments (DOE), analysis of variance and response surface methodology (RSM) were used to meet the stated objectives. From the results, it was observed that the oxygen flow rate has greater influence on coating porosity and hardness followed by LPG flow rate, powder feed rate and spray distance, respectively.