Institution
Annamalai University
Education•Chidambaram, Tamil Nadu, India•
About: Annamalai University is a education organization based out in Chidambaram, Tamil Nadu, India. It is known for research contribution in the topics: Lipid peroxidation & Antioxidant. The organization has 8098 authors who have published 10758 publications receiving 203872 citations.
Papers published on a yearly basis
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TL;DR: This article has been retracted because substantial parts of the text were copied from the following sources without proper attribution: Lam, K.S. and Aalbersberg, W. (2012), Marine actinomycetes: An ongoing source of novel bioactive metabolites.
157 citations
TL;DR: The study shows that MSFEt has hypoglycaemic action and prevents decrease in body weight and is mainly used in Indian folk medicine for the treatment of diabetes mellitus.
157 citations
TL;DR: The present study indicates that the phytochemicals derived from M. oleifera seeds extracts are effective mosquito vector control agents and the plant extracts may be used for further integrated pest management programs.
Abstract: Objective
To evaluate the larvicidal and pupicidal potential of the methanolic extracts from Moringa oleifera (M. oleifera) plant seeds against malarial vector Anopheles stephensi (A. stephensi) mosquitoes at different concentrations (20, 40, 60, 80 and 100 ppm).
157 citations
TL;DR: Both curcumin and its metabolite ThC exert neuroprotection against MPTP induced neurotoxicity in the model of Parkinson’s disease which may in part be due to inhibition of MAO-B activity.
Abstract: We investigated the effects of the polyphenolic compound curcumin and its metabolite tetrahydrocurcumin (ThC), in the model of Parkinson's disease induced in mice by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). In this model depletion of dopamine(DA) and DOPAC (3,4-dihydroxy phenyl acetic acid)) occurs with increased monoamine oxidase (MAO-B) activity. We used HPLC with electrochemical detection to measure DA and DOPAC respectively while MAO-B was assayed by spectroflourimetry using the conversion of the fluorogenic substrate, kyuramine. Systemic administration of curcumin (80 mg/kg i. p.) and tetrahydrocurcumin (60 mg/kg i. p.) significantly reversed the MPTP-induced depletion of DA and DOPAC. The MAO-B activity was also significantly inhibited by these compounds. The results showed that curcumin and tetrahydrocurcumin reversed the MPTP induced depletion of DA and DOPAC which may in part be due to inhibition of MAO-B activity. In conclusion, both curcumin and its metabolite ThC exert neuroprotection against MPTP induced neurotoxicity.
157 citations
TL;DR: Astaxanthin targets key molecules in oncogenic signaling pathways and induces apoptosis and is a promising candidate agent for cancer prevention and therapy.
157 citations
Authors
Showing all 8164 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Dinesh Mohan | 79 | 283 | 35775 |
| Sampath Parthasarathy | 77 | 268 | 34280 |
| Mandyam V. Srinivasan | 68 | 344 | 15572 |
| Leelavinothan Pari | 58 | 160 | 8374 |
| Venugopal P. Menon | 54 | 195 | 10111 |
| Kadarkarai Murugan | 54 | 286 | 9280 |
| V. Balasubramanian | 54 | 457 | 10951 |
| Marimuthu Govindarajan | 52 | 212 | 6738 |
| Annamalai Subramanian | 49 | 95 | 6021 |
| Meenakshisundaram Swaminathan | 48 | 239 | 8698 |
| Siddavaram Nagini | 47 | 185 | 7371 |
| Mohan K. Balasubramanian | 47 | 130 | 6238 |
| Subash C. B. Gopinath | 45 | 455 | 7855 |
| Sunil Sazawal | 44 | 111 | 9774 |
| Al. Ramanathan | 43 | 235 | 6132 |