Institution
Annamalai University
Education•Chidambaram, Tamil Nadu, India•
About: Annamalai University is a education organization based out in Chidambaram, Tamil Nadu, India. It is known for research contribution in the topics: Lipid peroxidation & Antioxidant. The organization has 8098 authors who have published 10758 publications receiving 203872 citations.
Papers published on a yearly basis
Papers
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TL;DR: Administration of the extract of T. cordifolia roots for 6 weeks resulted in a significant reduction in serum and tissue cholesterol, phospholipids and free fatty acids in alloxan diabetic rats and Insulin restored all the parameters to near normal values.
125 citations
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TL;DR: This work agreed with the potential biogenic TA-CuO NPs for promising in vitro photothermolysis of cancer cells, for the development of anticancer nanotherapeutics.
Abstract: In this report, copper oxide nanoparticles (TA-CuO NPs) were synthesized using cell-free extract of Trichoderma asperellum and assessed their photothermal induced anticancerous activity. The fungal mediated TA-CuO NPs was confirmed by the surface plasmon resonance at 285–295 nm. The amide (C O) and aromatic (C C) groups in secondary metabolites of the extract was found to be an encapsulating or reducing agents for TA-CuO NPs, as indicated by IR spectra. Crystalline nature by cubic face-centered structure of the TA-CuO NPs was confirmed by XRD and their size ranges from 10 to 190 nm and an average of 110 nm by particle size analyzer (PSA). The Ultra HRSEM study revealed spherical shaped TA-CuO NPs. The FETEM results were also in strong agreement with PSA and UHR SEM. The survey-scan spectrum of XPS indicated the presence of C1s (47.83%), Cu2p (16.11%), Na1s (2.2%) and O1s (33.86%). The cell death was significantly found higher in photothermal induced by near-infrared laser (TA-CuO NPs-NIR) treated than that of TA-CuO NPs treatment. The level of ROS (35.62%) was higher in the treated cells than that of the untreated control, in accordance with the nucleus damage and losses in the mitochondrial membrane potential (ΔΨm). The upregulation of Bcl-2 in the untreated cells and Cas-3 in TA-CuO NPs-NIR treated cells was confirmed by western blot analysis. This work agreed with the potential biogenic TA-CuO NPs for promising in vitro photothermolysis of cancer cells, for the development of anticancer nanotherapeutics.
124 citations
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TL;DR: The low availability of peroxidizable substrates and the enhanced antioxidant capacity in tumor tissues make them less susceptible to oxidative stress, conferring a selective growth advantage on tumor cells.
124 citations
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TL;DR: It is revealed that THC could afford a significant protection against erthromycin estolate-induced hepatocellular damage and had a better protective effect when compared with Silymarin, a reference drug.
124 citations
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TL;DR: In this article, the photocatalytic decolourisation and degradation of an azo dye Reactive Yellow 14 (RY14) in aqueous solution with TiO 2 -P25 (Degussa) as photocatalyst in slurry form have been investigated using solar light.
Abstract: The photocatalytic decolourisation and degradation of an azo dye Reactive Yellow 14 (RY14) in aqueous solution with TiO 2 -P25 (Degussa) as photocatalyst in slurry form have been investigated using solar light. The study on the effect of various photocatalysts on the decolourisation and degradation reveals the following order of reactivity: ZnO > TiO 2 -P25 > TiO 2 (anatase). CdS, Fe 2 O 3 and SnO 2 have negligible activity on RY14 decolourisation and degradation. The effects of various parameters such as catalyst loading and initial dye concentration on decolourisation and degradation have been investigated to find out optimum conditions. The decolourisation and degradation kinetics have been analysed. Both follow Langmuir kinetic model. A study on the effect of electron acceptors on photooxidation reveals that both decolourisation and degradation increase in the presence of H 2 O 2 , (NH 4 ) 2 S 2 O 8 and KBrO 3 to certain dosage beyond which the enhancement effect is negligible. Addition of dye assisting chemicals such as CO 3 2− and Cl − inhibits the dye removal rate.
123 citations
Authors
Showing all 8164 results
Name | H-index | Papers | Citations |
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Dinesh Mohan | 79 | 283 | 35775 |
Sampath Parthasarathy | 77 | 268 | 34280 |
Mandyam V. Srinivasan | 68 | 344 | 15572 |
Leelavinothan Pari | 58 | 160 | 8374 |
Venugopal P. Menon | 54 | 195 | 10111 |
Kadarkarai Murugan | 54 | 286 | 9280 |
V. Balasubramanian | 54 | 457 | 10951 |
Marimuthu Govindarajan | 52 | 212 | 6738 |
Annamalai Subramanian | 49 | 95 | 6021 |
Meenakshisundaram Swaminathan | 48 | 239 | 8698 |
Siddavaram Nagini | 47 | 185 | 7371 |
Mohan K. Balasubramanian | 47 | 130 | 6238 |
Subash C. B. Gopinath | 45 | 455 | 7855 |
Sunil Sazawal | 44 | 111 | 9774 |
Al. Ramanathan | 43 | 235 | 6132 |