Institution
Applied Science Private University
Education•Amman, Jordan•
About: Applied Science Private University is a education organization based out in Amman, Jordan. It is known for research contribution in the topics: Catalysis & Population. The organization has 4124 authors who have published 5299 publications receiving 116167 citations.
Papers published on a yearly basis
Papers
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TL;DR: It is demonstrated that AT1-PEG-DGL quickly accumulated in the MI heart during the desired early period, significantly outperforming the control group without AT1 targeting and a pronounced in-vivo anti-apoptosis effect was observed upon a single IV injection.
41 citations
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TL;DR: Interesterified fats containing palmitic acid induce atherosclerosis development by promoting cholesterol accumulation in LDL particles and macrophagic cells, activating the inflammatory process in LDLr-KO mice, and culminate in higher atherosclerotic lesion, macrophage infiltration and collagen content than PALM, STEAR, ST EAR INTER and PUFA.
Abstract: Interesterified fats are currently being used to replace trans fatty acids. However, their impact on biological pathways involved in the atherosclerosis development was not investigated. Weaning male LDLr-KO mice were fed for 16 weeks on a high-fat diet (40% energy as fat) containing polyunsaturated (PUFA), TRANS, palmitic (PALM), palmitic interesterified (PALM INTER), stearic (STEAR) or stearic interesterified (STEAR INTER). Plasma lipids, lipoprotein profile, arterial lesion area, macrophage infiltration, collagen content and inflammatory response modulation were determined. Macrophage cholesterol efflux and the arterial expression of cholesterol uptake and efflux receptors were also performed. The interesterification process did not alter plasma lipid concentrations. Although PALM INTER did not increase plasma cholesterol concentration as much as TRANS, the cholesterol enrichment in the LDL particle was similar in both groups. Moreover, PALM INTER induced the highest IL-1β, MCP-1 and IL-6 secretion from peritoneal macrophages as compared to others. This inflammatory response elicited by PALM INTER was confirmed in arterial wall, as compared to PALM. These deleterious effects of PALM INTER culminate in higher atherosclerotic lesion, macrophage infiltration and collagen content than PALM, STEAR, STEAR INTER and PUFA. These events can partially be attributed to a macrophage cholesterol accumulation, promoted by apoAI and HDL 2 -mediated cholesterol efflux impairment and increased Olr-1 and decreased Abca1 and Nr1h3 expressions in the arterial wall. Interesterified fats containing palmitic acid induce atherosclerosis development by promoting cholesterol accumulation in LDL particles and macrophagic cells, activating the inflammatory process in LDLr-KO mice.
41 citations
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TL;DR: In this paper, different pressure control schemes were tested by 1-D core-flooding experiments to obtain an optimized one, and numerical simulations were conducted to history match all experimental data to understand the mechanisms and characteristics of different CO2 flooding strategies.
41 citations
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TL;DR: In this paper, the effects of different heat treatments on the microstructure and mechanical properties of AA2618 DC cast alloy were investigated using scanning electron microscopy (SEM), transmission electron microscope (TEM), and hardness and tensile testing.
41 citations
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TL;DR: In this article, the authors used a screen-printed sensor based on graft-polymerized MgO-templated carbon onto which lactate oxidase and 1,2-naphthoquinone were immobilized.
41 citations
Authors
Showing all 4150 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hua Zhang | 163 | 1503 | 116769 |
Menachem Elimelech | 157 | 547 | 95285 |
Yu Huang | 136 | 1492 | 89209 |
Dmitri Golberg | 129 | 1024 | 61788 |
Andrea Carlo Marini | 123 | 1236 | 72959 |
Dionysios D. Dionysiou | 116 | 675 | 48449 |
Liyuan Han | 114 | 766 | 65277 |
Shunichi Fukuzumi | 111 | 1256 | 52764 |
John A. Stankovic | 109 | 559 | 51329 |
Judea Pearl | 107 | 512 | 83978 |
Feng Wang | 107 | 1136 | 64644 |
O. C. Zienkiewicz | 107 | 455 | 71204 |
Jeffrey I. Zink | 99 | 509 | 42667 |
Kazuhiro Hono | 98 | 878 | 33534 |
Robert W. Boyd | 98 | 1161 | 37321 |