Institution
Applied Science Private University
Education•Amman, Jordan•
About: Applied Science Private University is a education organization based out in Amman, Jordan. It is known for research contribution in the topics: Population & Catalysis. The organization has 4124 authors who have published 5299 publications receiving 116167 citations.
Papers published on a yearly basis
Papers
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TL;DR: Experimental results show that mPEG-SS-PLL(15)-star represents a promising design for future nonviral gene delivery applications with high DNA binding ability, low cytotoxicity, and high transfection efficiency.
114 citations
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TL;DR: In this article, the carbon monoxide (CO) tolerance performance of polymer electrode fuel cells (PEFCs) was studied for a catalyst composed of graphene nanosheets (GNS) with sub-nano-Pt clusters.
114 citations
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TL;DR: A mathematical model for advective-diffusive-reactive solute transport due to non-Newtonian fluid flows in a fracture surrounded by a tight porous medium is presented in this article.
114 citations
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TL;DR: It is shown that microRNA-128 is upregulated in CMs during the postnatal switch from proliferation to terminal differentiation, suggesting that miR-128 serves as a critical regulator of endogenous CM proliferation, and might be a novel therapeutic target for heart repair.
Abstract: The goal of replenishing the cardiomyocyte (CM) population using regenerative therapies following myocardial infarction (MI) is hampered by the limited regeneration capacity of adult CMs, partially due to their withdrawal from the cell cycle. Here, we show that microRNA-128 (miR-128) is upregulated in CMs during the postnatal switch from proliferation to terminal differentiation. In neonatal mice, cardiac-specific overexpression of miR-128 impairs CM proliferation and cardiac function, while miR-128 deletion extends proliferation of postnatal CMs by enhancing expression of the chromatin modifier SUZ12, which suppresses p27 (cyclin-dependent kinase inhibitor) expression and activates the positive cell cycle regulators Cyclin E and CDK2. Furthermore, deletion of miR-128 promotes cell cycle re-entry of adult CMs, thereby reducing the levels of fibrosis, and attenuating cardiac dysfunction in response to MI. These results suggest that miR-128 serves as a critical regulator of endogenous CM proliferation, and might be a novel therapeutic target for heart repair.
113 citations
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TL;DR: In this paper, the authors investigated the bioaccumulation and uptake of antimony in a highly contaminated stream near the Hillgrove antimony-gold mine in NSW, Australia, and reports high Sb (and As) concentrations in many components of the ecosystem consisting of three trophic levels, but limited uptake into aboveground parts of riparian vegetation.
Abstract: Environmental context. Concern over the presence of antimony (Sb) in the environment because of chemical similarities with arsenic (As) has prompted a need to better understand its environmental behaviour and risks. The present study investigates the bioaccumulation and uptake of antimony in a highly contaminated stream near the Hillgrove antimony–gold mine in NSW, Australia, and reports high Sb (and As) concentrations in many components of the ecosystem consisting of three trophic levels, but limited uptake into aboveground parts of riparian vegetation. The data suggest that Sb can transfer into upper trophic levels of a creek ecosystem, but that direct exposure of creek fauna to creek sediment and soil, water and aquatic autotrophs are more important metalloid uptake routes than exposure via riparian vegetation. Abstract. Bioaccumulation and uptake of antimony (Sb) were investigated in a highly contaminated stream, Bakers Creek, running adjacent to mining and processing of Sb–As ores at Hillgrove Mine, NSW, Australia. Comparisons with arsenic (As) were included owing to its co-occurrence at high concentrations. Mean metalloid creek rhizome sediment concentrations were 777 ± 115 μg g–1 Sb and 60 ± 6 μg g–1 As, with water concentrations at 381 ± 23 μg L–1 Sb and 46 ± 2 μg L–1 As. Antimony and As were significantly elevated in aquatic autotrophs (96–212 μg g–1 Sb and 32–245 μg g–1 As) but Sb had a lower uptake efficiency. Both metalloids were elevated in all macroinvertebrates sampled (94–316 μg g–1 Sb and 1.8–62 μg g–1 As) except Sb in gastropods. Metalloids were detected in upper trophic levels although biomagnification was not evident. Metalloid transfer to riparian vegetation leaves from roots and rhizome soil was low but rhizome soil to leaf As concentration ratios were up to 2–3 times greater than Sb concentration ratios. Direct exposure to the rhizosphere sediments and soils, water ingestion and consumption of aquatic autotrophs appear to be the major routes of Sb and As uptake for the fauna of Bakers Creek.
112 citations
Authors
Showing all 4150 results
Name | H-index | Papers | Citations |
---|---|---|---|
Hua Zhang | 163 | 1503 | 116769 |
Menachem Elimelech | 157 | 547 | 95285 |
Yu Huang | 136 | 1492 | 89209 |
Dmitri Golberg | 129 | 1024 | 61788 |
Andrea Carlo Marini | 123 | 1236 | 72959 |
Dionysios D. Dionysiou | 116 | 675 | 48449 |
Liyuan Han | 114 | 766 | 65277 |
Shunichi Fukuzumi | 111 | 1256 | 52764 |
John A. Stankovic | 109 | 559 | 51329 |
Judea Pearl | 107 | 512 | 83978 |
Feng Wang | 107 | 1136 | 64644 |
O. C. Zienkiewicz | 107 | 455 | 71204 |
Jeffrey I. Zink | 99 | 509 | 42667 |
Kazuhiro Hono | 98 | 878 | 33534 |
Robert W. Boyd | 98 | 1161 | 37321 |