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Institution

Applied Science Private University

EducationAmman, Jordan
About: Applied Science Private University is a education organization based out in Amman, Jordan. It is known for research contribution in the topics: Population & Catalysis. The organization has 4124 authors who have published 5299 publications receiving 116167 citations.


Papers
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Journal ArticleDOI
TL;DR: The metabolically active cancer cells are shown to a unique surface electrostatic pattern that can be used for recovering cancer cells from the circulating blood and other solutions.
Abstract: A set of electrostatically charged, fluorescent, and superparamagnetic nanoprobes was developed for targeting cancer cells without using any molecular biomarkers. The surface electrostatic properties of the established cancer cell lines and primary normal cells were characterized by using these nanoprobes with various electrostatic signs and amplitudes. All twenty two randomly selected cancer cell lines of different organs, but not normal control cells, bound specifically to the positively charged nanoprobes. The relative surface charges of cancer cells could be quantified by the percentage of cells captured magnetically. The activities of glucose metabolism had a profound impact on the surface charge level of cancer cells. The data indicate that an elevated glycolysis in the cancer cells led to a higher level secretion of lactate. The secreted lactate anions are known to remove the positive ions, leaving behind the negative changes on the cell surfaces. This unique metabolic behavior is responsible for generating negative cancer surface charges in a perpetuating fashion. The metabolically active cancer cells are shown to a unique surface electrostatic pattern that can be used for recovering cancer cells from the circulating blood and other solutions.

274 citations

Journal ArticleDOI
TL;DR: Inhibition of targets such as cholesterol synthesis and metabolites, reactive oxygen species and hypoxia, macrophage activation and conversion, indoleamine 2,3-dioxygenase regulation of dendritic cells, vascular endothelial growth factor regulation of angiogenesis, fibrosis inhibition, endoglin, and Janus kinase signaling emerge as examples of important potential nexuses in the regulation of tumorigenesis and the tumor microenvironment that can be targeted.

270 citations

Journal ArticleDOI
TL;DR: In this paper, an electromechanical, two-axis sun tracking system is designed and constructed using an open-loop system where the programmable logic controller is used to control the motion of the sun tracking surface.

267 citations

Journal ArticleDOI
TL;DR: In this article, the diffusion-controlled coarsening behavior of precipitates situated on both high-angle and low-angle grain boundaries has been investigated theoretically, and the effect of volume fraction, φ, is included in the calculations.

262 citations

Journal ArticleDOI
TL;DR: In this paper, an analysis of impact fracture surfaces performed on polyester B composites clearly demonstrated better interfacial adhesion between fibre and matrix, and a moisture absorption test also showed that polyester b composites gave the most superior bonding and adhesion of all the other polyester-kenaf composites.

260 citations


Authors

Showing all 4150 results

NameH-indexPapersCitations
Hua Zhang1631503116769
Menachem Elimelech15754795285
Yu Huang136149289209
Dmitri Golberg129102461788
Andrea Carlo Marini123123672959
Dionysios D. Dionysiou11667548449
Liyuan Han11476665277
Shunichi Fukuzumi111125652764
John A. Stankovic10955951329
Judea Pearl10751283978
Feng Wang107113664644
O. C. Zienkiewicz10745571204
Jeffrey I. Zink9950942667
Kazuhiro Hono9887833534
Robert W. Boyd98116137321
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20239
202255
2021599
2020473
2019404
2018355