Institution
Atomic Energy of Canada Limited
Company•Ottawa, Ontario, Canada•
About: Atomic Energy of Canada Limited is a company organization based out in Ottawa, Ontario, Canada. It is known for research contribution in the topics: Zirconium alloy & Neutron. The organization has 4845 authors who have published 4826 publications receiving 102951 citations.
Topics: Zirconium alloy, Neutron, Zirconium, Hydrogen, Neutron scattering
Papers published on a yearly basis
Papers
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01 Feb 1985
TL;DR: In this paper, a feasibility study shows that the key to reliable and cost-effective automatic reading of drawings is detailed planning of an operator-assisted system, and that this is the case for most drawings.
Abstract: A Canadian feasibility study shows that the key to reliable and cost-effective automatic reading of drawings is detailed planning of an operator-assisted system.
54 citations
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54 citations
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TL;DR: In this article, a temperature-time-transformation (TTT) diagram was developed for the β-phase in Zr-2.5Nb pressure tubes, and the results showed that the morphology and/or physical state of the β phase has a significant effect on the transformation behaviour compared with a bulk Zr−20-wt%Nb alloy.
54 citations
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01 Jan 1977TL;DR: It is led to conclude that DNA damage can lead to congenital malformations; thus, enzymatic DNA repair processes play a vital role in normal neonatal development.
Abstract: A unique feature of ataxia telangiectasia (AT), a hereditary multisystem disease, is extreme sensitivity to ionizing radiation, observed both clinically and in cell culture. Hence, we have measured the DNA repair capabilities of ten diploid fibroblast strains derived from unrelated AT donors, following anoxic 60Co γ-irradiation. Compared to two control strains, six of the ten mutant strains are markedly deficient in γ-induced repair replication. Two defective strains were defined further. While capable of rejoining single-strand breaks normally, both are impaired in the initial incision step in excision repair of base defects, assayed as γ-modified sites sensitive to a Micrococcus luteus endonuclease activity. Cell fusion studies assign three repair-deficient strains to two complementation groups; this result, coupled with a normal repair-replication ability in four of the ten AT strains, indicates genetic heterogeneity in the disease. AT strains appear otherwise normal, including their ability to repair UV damage. Aside from providing molecular insight into this complex disorder, our findings characterize AT as a γ-ray analogue of the UV-sensitive skin disease, xeroderma pigmentosum. Moreover, since AT patients are cancer-prone, faulty DNA repair is implicated in neoplastic transformation. Finally, given that (i) impaired embryonic differentiation best explains the clinical features of AT and (ii) defective DNA repair is of etiological relevance, we are led to conclude that DNA damage can lead to congenital malformations; thus, enzymatic DNA repair processes play a vital role in normal neonatal development.
54 citations
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TL;DR: The exogenous enzyme shortens the delay in recovery of the white blood cells, particularly after x-ray doses of 550 and 675 rad, and the earlier hematological recovery is attributable to the known radioprotective effect of the enzyme on bone marrow stem cells.
53 citations
Authors
Showing all 4845 results
Name | H-index | Papers | Citations |
---|---|---|---|
Henry P. Schwarcz | 78 | 351 | 20863 |
Jonathan N. Glickman | 72 | 172 | 24025 |
Andrej Atrens | 69 | 417 | 21741 |
See Leang Chin | 67 | 460 | 17181 |
Purnendu K. Dasgupta | 62 | 506 | 16779 |
John Katsaras | 55 | 220 | 9263 |
Jing-Li Luo | 55 | 436 | 10963 |
Charles Gale | 53 | 331 | 10903 |
Sanjoy Banerjee | 52 | 229 | 8880 |
Yoshio Takahashi | 50 | 403 | 9801 |
Peter Sigmund | 49 | 220 | 11795 |
Michael P. Païdoussis | 46 | 165 | 8825 |
Wei-Kan Chu | 46 | 445 | 8616 |
A. G. W. Cameron | 45 | 123 | 10111 |
Erland M. Schulson | 44 | 245 | 6966 |