Australian Catholic University

About: Australian Catholic University is a education organization based out in Brisbane, Queensland, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 2721 authors who have published 10013 publications receiving 215248 citations. The organization is also known as: ACU & ACU National.

The Impact of Physical Activity on Brain Structure and Function in Youth: A Systematic Review.

Abstract: CONTEXT: Advances in neuroimaging techniques have resulted in an exponential increase in the number of studies investigating the effects of physical activity on brain structure and function. Authors of studies have linked physical activity and fitness with brain regions and networks integral to cognitive function and scholastic performance in children and adolescents but findings have not been synthesized. OBJECTIVE: To conduct a systematic review of studies in which the impact of physical activity on brain structure and function in children and adolescents is examined. DATA SOURCES: Six electronic databases (PubMed, PsychINFO, Scopus, Ovid Medline, SportDiscus, and Embase) were systematically searched for experimental studies published between 2002 and March 1, 2019. STUDY SELECTION: Two reviewers independently screened studies for inclusion according to predetermined criteria. DATA EXTRACTION: Two reviewers independently extracted data for key variables and synthesized findings qualitatively. RESULTS: Nine studies were included (task-based functional MRI [n = 4], diffusion tensor imaging [n = 3], arterial spin labeling [n = 1], and resting-state functional MRI [n = 1]) in which results for 5 distinct and 4 similar study samples aged 8.7 ± 0.6 to 10.2 ± 1.0 years and typically of relatively low socioeconomic status were reported. Effects were reported for 12 regions, including frontal lobe (n = 3), parietal lobe (n = 3), anterior cingulate cortex (n = 2), hippocampus (n = 1), and several white matter tracts and functional networks. LIMITATIONS: Findings need to be interpreted with caution as quantitative syntheses were not possible because of study heterogeneity. CONCLUSIONS: There is evidence from randomized controlled trials that participation in physical activity may modify white matter integrity and activation of regions key to cognitive processes. Additional larger hypothesis-driven studies are needed to replicate findings.

Importance, Reliability, and Usefulness of Acceleration Measures in Team Sports.

Abstract: Delaney, JA, Cummins, CJ, Thornton, HR, and Duthie, GM. Importance, reliability and usefulness of acceleration measures in team sports. J Strength Cond Res 32(12): 3494-3502, 2018-The ability to accelerate, decelerate, and change direction efficiently is imperative to successful team sports performance. Traditional intensity-based thresholds for acceleration and deceleration may be inappropriate for time-series data and have been shown to exhibit poor reliability, suggesting other techniques may be preferable. This study assessed movement data from one professional rugby league team throughout 2 full seasons and 1 preseason period. Using both 5 and 10 Hz global positioning systems (GPS) units, a range of acceleration-based variables were evaluated for their interunit reliability, ability to discriminate between positions, and associations with perceived muscle soreness. The reliability of 5 Hz global positioning systems for measuring acceleration and deceleration ranged from good to poor (CV = 3.7-27.1%), with the exception of high-intensity deceleration efforts (CV = 11.1-11.8%), the 10 Hz units exhibited moderate-to-good interunit reliability (CV = 1.2-6.9%). Reliability of average metrics (average acceleration/deceleration, average acceleration, and average deceleration) ranged from good to moderate (CV = 1.2-6.5%). Substantial differences were detected between positions using time spent accelerating and decelerating for all magnitudes, but these differences were less clear when considering the count or distance above acceleration/deceleration thresholds. All average metrics detected substantial differences between positions. All measures were similarly related to perceived muscle soreness, with the exception of high-intensity acceleration and deceleration counts. This study has proposed that averaging the acceleration/deceleration demands over an activity may be a more appropriate method compared with threshold-based methods, because a greater reliability between units, while not sacrificing sensitivity to within-subject and between-subject changes.

A systematic review of elastography, electrical impedance scanning, and digital infrared thermography for breast cancer screening and diagnosis

Abstract: The objective of this study aimed to systematically identify and evaluate all the available evidence of safety, effectiveness and diagnostic accuracy for three emerging classes of technology promoted for breast cancer screening and diagnosis: Digital infrared thermal imaging (DITI), electrical impedance scanning (EIS) and elastography. A systematic search of seven biomedical databases (EMBASE, PubMed, Web of Science, CRD, CINAHL, Cochrane Library, Current Contents Connect) was conducted through March 2011, along with a manual search of reference lists from relevant studies. The principal outcome measures were safety, effectiveness, and diagnostic accuracy. Data were extracted using a standardised form, and validated for accuracy by the secondary authors. Study quality was appraised using the quality assessment of diagnostic accuracy studies tool, while heterogeneity was assessed using forest plots, Cooks’ distance and standardised residual scatter plots, and I 2 statistics. From 6,808 search results, 267 full-text articles were assessed, of which 60 satisfied the inclusion criteria. No effectiveness studies were identified. Only one EIS screening accuracy study was identified, while all other studies involved symptomatic populations. Significant heterogeneity was present among all device classes, limiting the potential for meta-analyses. Sensitivity and specificity varied greatly for DITI (Sens 0.25–0.97, Spec 0.12–0.85), EIS (Sens 0.26–0.98, Spec 0.08–0.81) and ultrasound elastography (Sens 0.35–1.00, Spec 0.21–0.99). It is concluded that there is currently insufficient evidence to recommend the use of these technologies for breast cancer screening. Moreover, the high level of heterogeneity among studies of symptomatic women limits inferences that may be drawn regarding their use as diagnostic tools. Future research employing standardised imaging, research and reporting methods is required.

Preoperative radiation and free flap outcomes for head and neck reconstruction: a systematic review and meta-analysis.

Abstract: Background There is a general consensus among reconstructive surgeons that preoperative radiotherapy is associated with a higher risk of flap failure and complications in head and neck surgery. Opinion is also divided regarding the effects of radiation dose on free flap outcomes and timing of preoperative radiation to minimize adverse outcomes. Our meta-analysis will attempt to address these issues. Method A systematic review of the literature was conducted in concordance to PRISMA protocol. Data were combined using STATA 12 and Open Meta-Analyst software programmes. Results Twenty-four studies were included comparing 2842 flaps performed in irradiated fields and 3491 flaps performed in non-irradiated fields. Meta-analysis yielded statistically significant risk ratios for flap failure (RR 1.48, P = 0.004), complications (RR 1.84, P 60 Gy radiation had a non-statistically significant higher risk of flap failure (RR 1.61, P = 0.145). Conclusion Preoperative radiation is associated with a statistically significant increased risk of flap complications, failure and fistula. Preoperative radiation in excess of 60 Gy after radiotherapy represents a potential risk factor for increased flap loss and should be avoided where possible.