Institution
Australian National University
Education•Canberra, Australian Capital Territory, Australia•
About: Australian National University is a education organization based out in Canberra, Australian Capital Territory, Australia. It is known for research contribution in the topics: Population & Galaxy. The organization has 34419 authors who have published 109261 publications receiving 4315448 citations. The organization is also known as: The Australian National University & ANU.
Topics: Population, Galaxy, Stars, Zircon, Politics
Papers published on a yearly basis
Papers
More filters
••
Washington University in St. Louis1, Australian National University2, University of Oxford3, University of Adelaide4, University of Sydney5, Pennsylvania State University6, Wellcome Trust Sanger Institute7, University of Cambridge8, University of Oviedo9, University of Washington10, Walter and Eliza Hall Institute of Medical Research11, Weizmann Institute of Science12, Institute for Systems Biology13, University of Melbourne14, Hudson Institute of Medical Research15, Louisiana State University16, University of Canterbury17, University of Münster18, Howard Hughes Medical Institute19, Monash University20, West Virginia University21, New York University22, Institut national de la recherche agronomique23, Iowa State University24, Broad Institute25
TL;DR: It is found that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypUS biology.
Abstract: We present a draft genome sequence of the platypus, Ornithorhynchus anatinus This monotreme exhibits a fascinating combination of reptilian and mammalian characters For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles Analysis of the first monotreme genome aligned these features with genetic innovations We find that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus biology Expansions of protein, non-protein-coding RNA and microRNA families, as well as repeat elements, are identified Sequencing of this genome now provides a valuable resource for deep mammalian comparative analyses, as well as for monotreme biology and conservation
653 citations
••
TL;DR: There are some recent radiations in CYP6, CYP9 and certain CCE clades in A. mellifera that could be associated with the evolution of the hormonal and chemosensory processes underpinning its highly organized eusociality.
Abstract: The honeybee genome has substantially fewer protein coding genes (approximate to 11 000 genes) than Drosophila melanogaster (approximate to 13 500) and Anopheles gambiae (approximate to 14 000). Some of the most marked differences occur in three superfamilies encoding xenobiotic detoxifying enzymes. Specifically there are only about half as many glutathione-S-transferases (GSTs), cytochrome P450 monooxygenases (P450s) and carboxyl/cholinesterases (CCEs) in the honeybee. This includes 10-fold or greater shortfalls in the numbers of Delta and Epsilon GSTs and CYP4 P450s, members of which clades have been recurrently associated with insecticide resistance in other species. These shortfalls may contribute to the sensitivity of the honeybee to insecticides. On the other hand there are some recent radiations in CYP6, CYP9 and certain CCE clades in A. mellifera that could be associated with the evolution of the hormonal and chemosensory processes underpinning its highly organized eusociality.
653 citations
••
University of Cambridge1, University of Sheffield2, University of Oxford3, University of California, Berkeley4, University of Leeds5, Technion – Israel Institute of Technology6, Imperial College London7, Queen's University Belfast8, Swansea University9, University of Exeter10, University of Sussex11, University of Aberdeen12, Bangor University13, University of Warwick14, Australian National University15, Environmental Change Institute16, University of Reading17, University of Edinburgh18, Microsoft19, Rockefeller University20, University of Zurich21, Swedish University of Agricultural Sciences22, Helmholtz Centre for Environmental Research - UFZ23
TL;DR: The 100th anniversary of the British Ecological Society in 2013 is an opportune moment to reflect on the current status of ecology as a science and look forward to high-light priorities for future work.
Abstract: Summary 1. Fundamental ecological research is both intrinsically interesting and provides the basic knowledge required to answer applied questions of importance to the management of the natural world. The 100th anniversary of the British Ecological Society in 2013 is an opportune moment to reflect on the current status of ecology as a science and look forward to high-light priorities for future work.
652 citations
••
TL;DR: In this article, the authors present the standard intensity profile, and its various guises such as the luminosity, surface-brightness, and aperture-magnitude profile.
Abstract: Given the growing use of Sersic's (1963, 1968) R 1/n model for describing the stellar distributions in galaxies, and the lack of any single reference that provides the various associated mathematical expressions, we have endeavoured to compile such a resource here. We present the standard intensity profile, and its various guises such as the luminosity, surface-brightness, and aperture-magnitude profile. Expressions to transform the effective surface brightness into the mean effective and central surface brightness are also given, as is the expression to transform between effective radii and exponential scale-lengths. We additionally provide expressions for deriving the 'concentration' of an R 1/n profile, and two useful equations for the logarithmic slope of the light-profile are given. Petrosian radii and fluxes are also derived for a range of Sersic profiles and compared with the effective radii and total flux. Similarly, expressions to obtain Kron radii and fluxes are presented as a function of the Sersic index n and the number of effective radii sampled. Illustrative figures are provided throughout. Finally, the core-Sersic model, consisting of an inner power-law and an outer Sersic function, is presented.
651 citations
••
TL;DR: The antimicrobial activity of eight components of tea tree oil was evaluated using disc diffusion and broth microdilution methods and reasonable agreement between minimum inhibitory concentrations and zones of inhibition was found.
Abstract: Tea tree oil, or the essential oil of Melaleuca alternifolia, is becoming increasingly popular as a naturally occurring antimicrobial agent. The antimicrobial activity of eight components of tea tree oil was evaluated using disc diffusion and broth microdilution methods. Attempts were also made to overcome methodological problems encountered with testing compounds which have limited solubility in aqueous media. After assessing media with and without solubilizing agents, the disc diffusion method was used to determine the susceptibility of a range of micro-organisms to 1,8-cineole, 1-terpinen-4-ol, rho-cymene, linalool, alpha-terpinene, gamma-terpinene, alpha-terpineol and terpinolene. While the disc diffusion method lacked reproducibility, it was considered useful as a procedure for screening for antimicrobial activity. Terpinen-4-ol was active against all the test organisms while rho-cymene demonstrated no antimicrobial activity. Linalool and alpha-terpineol were active against all organisms with the exception of Pseudomonas aeruginosa. Minimum inhibitory and minimum cidal concentrations of each component against Candida albicans, Escherichia coli and Staphylococcus aureus were determined using a broth microdilution method. Modifications to this method overcame solubility and turbidity problems associated with the oil components and allowed the antimicrobial activity of each of the components to be quantified reproducibly. There was reasonable agreement between minimum inhibitory concentrations and zones of inhibition. These results may have significant implications for the future development of tea tree oil as an antimicrobial agent.
651 citations
Authors
Showing all 34925 results
Name | H-index | Papers | Citations |
---|---|---|---|
Cyrus Cooper | 204 | 1869 | 206782 |
Nicholas G. Martin | 192 | 1770 | 161952 |
David R. Williams | 178 | 2034 | 138789 |
Krzysztof Matyjaszewski | 169 | 1431 | 128585 |
Anton M. Koekemoer | 168 | 1127 | 106796 |
Robert G. Webster | 158 | 843 | 90776 |
Ashok Kumar | 151 | 5654 | 164086 |
Andrew White | 149 | 1494 | 113874 |
Bernhard Schölkopf | 148 | 1092 | 149492 |
Paul Mitchell | 146 | 1378 | 95659 |
Liming Dai | 141 | 781 | 82937 |
Thomas J. Smith | 140 | 1775 | 113919 |
Michael J. Keating | 140 | 1169 | 76353 |
Joss Bland-Hawthorn | 136 | 1114 | 77593 |
Harold A. Mooney | 135 | 450 | 100404 |