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Institution

Australian National University

EducationCanberra, Australian Capital Territory, Australia
About: Australian National University is a education organization based out in Canberra, Australian Capital Territory, Australia. It is known for research contribution in the topics: Population & Galaxy. The organization has 34419 authors who have published 109261 publications receiving 4315448 citations. The organization is also known as: The Australian National University & ANU.
Topics: Population, Galaxy, Stars, Zircon, Politics


Papers
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Journal ArticleDOI
TL;DR: In this paper, a functional understanding of the physical and biological processes underlying mangrove ecosystem dynamics is presented. But this process is not suitable for the management of mangroves.
Abstract: Mangrove forests are of major ecological and commercial importance, yet the future of these resources is threatened by pollution, development and over-exploitation. There is an urgent need to develop sound management practices based on a functional understanding of the physical and biological processes underlying mangrove ecosystem dynamics. Such biological processes include dispersal (Rabinowitz 1978), herbivory (Smith 1987) and the physiological bases of species interactions and responses to environmental factors. Understanding these processes is essential for the development of more comprehensive and predictive modelling of mangrove ecosystem dynamics than has previously been possible.

465 citations

Journal ArticleDOI
TL;DR: Heparan sulphate is involved in the initial adhesion of leukocytes to the inflamed endothelium, the subsequent chemokine-mediated transmigration through the vessel wall and the establishment of both acute and chronic inflammatory reactions.
Abstract: The polysaccharide heparan sulphate is ubiquitously expressed as a proteoglycan in extracellular matrices and on cell surfaces. Heparan sulphate has marked sequence diversity that allows it to specifically interact with many proteins. This Review focuses on the multiple roles of heparan sulphate in inflammatory responses and, in particular, on its participation in almost every stage of leukocyte transmigration through the blood-vessel wall. Heparan sulphate is involved in the initial adhesion of leukocytes to the inflamed endothelium, the subsequent chemokine-mediated transmigration through the vessel wall and the establishment of both acute and chronic inflammatory reactions.

465 citations

Journal ArticleDOI
TL;DR: A central function of the major histo-compatibility (H) antigens may be to signal changes in self to the immune system, with extreme genetic polymorphism found in the major H antigen systems of higher vertebrates reflecting evolutionary pressure exerted by this immunological surveillance mechanism.

464 citations

Journal ArticleDOI
B. P. Abbott1, Richard J. Abbott1, T. D. Abbott2, Sheelu Abraham3  +1215 moreInstitutions (134)
TL;DR: In this paper, the mass, spin, and redshift distributions of binary black hole (BBH) mergers with LIGO and Advanced Virgo observations were analyzed using phenomenological population models.
Abstract: We present results on the mass, spin, and redshift distributions with phenomenological population models using the 10 binary black hole (BBH) mergers detected in the first and second observing runs completed by Advanced LIGO and Advanced Virgo. We constrain properties of the BBH mass spectrum using models with a range of parameterizations of the BBH mass and spin distributions. We find that the mass distribution of the more massive BH in such binaries is well approximated by models with no more than 1% of BHs more massive than 45 M and a power-law index of (90% credibility). We also show that BBHs are unlikely to be composed of BHs with large spins aligned to the orbital angular momentum. Modeling the evolution of the BBH merger rate with redshift, we show that it is flat or increasing with redshift with 93% probability. Marginalizing over uncertainties in the BBH population, we find robust estimates of the BBH merger rate density of R= (90% credibility). As the BBH catalog grows in future observing runs, we expect that uncertainties in the population model parameters will shrink, potentially providing insights into the formation of BHs via supernovae, binary interactions of massive stars, stellar cluster dynamics, and the formation history of BHs across cosmic time.

464 citations

Journal ArticleDOI
TL;DR: Significant odds ratios were found for 4 variables: a history of either dementia, probable AD, or Down's syndrome in a 1st-degree relative, and underactivity as a behavioral trait in both the recent and more distant past.
Abstract: We conducted a case-control study of clinically diagnosed Alzheimer's disease (AD) on 170 cases aged 52 to 96 years, and 170 controls matched for age, sex and, where possible, the general practice of origin Trained lay interviewers naive to the hypotheses and to the clinical status of the elderly person carried out risk-factor interviews with informants Significant odds ratios were found for 4 variables: a history of either dementia, probable AD, or Down's syndrome in a 1st-degree relative, and underactivity as a behavioral trait in both the recent and more distant past Previously reported or suggested associations not confirmed by this study include head injury, starvation, thyroid disease, analgesic abuse, antacid use (aluminum exposure), alcohol abuse, smoking, and being left-handed

464 citations


Authors

Showing all 34925 results

NameH-indexPapersCitations
Cyrus Cooper2041869206782
Nicholas G. Martin1921770161952
David R. Williams1782034138789
Krzysztof Matyjaszewski1691431128585
Anton M. Koekemoer1681127106796
Robert G. Webster15884390776
Ashok Kumar1515654164086
Andrew White1491494113874
Bernhard Schölkopf1481092149492
Paul Mitchell146137895659
Liming Dai14178182937
Thomas J. Smith1401775113919
Michael J. Keating140116976353
Joss Bland-Hawthorn136111477593
Harold A. Mooney135450100404
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023280
2022773
20215,261
20205,464
20195,109
20184,825