Institution
Banaras Hindu University
Education•Varanasi, Uttar Pradesh, India•
About: Banaras Hindu University is a education organization based out in Varanasi, Uttar Pradesh, India. It is known for research contribution in the topics: Population & Catalysis. The organization has 11858 authors who have published 23917 publications receiving 464677 citations. The organization is also known as: Kashi Hindu Vishvavidyalay & Benares Hindu University.
Topics: Population, Catalysis, Dielectric, Alloy, Raman spectroscopy
Papers published on a yearly basis
Papers
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TL;DR: The oxygen and nitrogen donor atoms from carboxyl and amino groups were found to play a vital role in metal biosorption by Microcystis cell walls, and ion exchange mechanisms were involved in the biosor adaptation of test metals.
154 citations
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TL;DR: In this paper, a one-dimensional advection-diffusion equation with variable coefficients is solved for three dispersion problems: (i) solute dispersion along steady flow through an inhomogeneous medium, (ii) temporally dependent solute dispersions along uniform flow through homogeneous medium and (iii) solutespersistent flow through inhomogenous medium.
153 citations
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National Medical College1, Banaras Hindu University2, Ganesh Shankar Vidyarthi Memorial Medical College3, Government Medical College, Thiruvananthapuram4, King George's Medical University5, Sher-I-Kashmir Institute of Medical Sciences6, Fortis Healthcare7, All India Institute of Medical Sciences8, University of Washington9, Indian Institute of Health Management Research10
TL;DR: Hypersensitivity pneumonitis was the most common new‐onset ILD in India, followed by CTD‐ILD and idiopathic pulmonary fibrosis; diagnoses varied between site investigators and CILD experts, emphasizing the value of MDD in ILD diagnosis.
Abstract: Rationale: Interstitial lung disease (ILD) is a heterogeneous group of acute and chronic inflammatory and fibrotic lung diseases. Existing ILD registries have had variable findings. Little is known about the clinical profile of ILDs in India.Objectives: To characterize new-onset ILDs in India by creating a prospective ILD using multidisciplinary discussion (MDD) to validate diagnoses.Methods: Adult patients of Indian origin living in India with new-onset ILD (27 centers, 19 Indian cities, March 2012–June 2015) without malignancy or infection were included. All had connective tissue disease (CTD) serologies, spirometry, and high-resolution computed tomography chest. ILD pattern was defined by high-resolution computed tomography images. Three groups independently made diagnoses after review of clinical data including that from prompted case report forms: local site investigators, ILD experts at the National Data Coordinating Center (NDCC; Jaipur, India) with MDD, and experienced ILD experts at the Center fo...
153 citations
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TL;DR: It is concluded that the hsromega-n transcripts play essential structural and functional roles in organizing and establishing the hnRNP-containing omega speckles and thus regulate the trafficking and availability of hnRNPs and other related RNA binding proteins in the cell nucleus.
Abstract: Fluorescence RNA:RNA in situ hybridization studies in various larval and adult cell types of Drosophila melanogaster showed that the noncoding hsr-omega nuclear (hsrω-n) transcripts were present in the form of many small speckles. These speckles, which we name ‘omega speckles’, were distributed in the interchromatin space in close proximity to the chromatin. The only chromosomal site where hsrω-n transcripts localized was the 93D locus or the hsrω gene itself. The number of nucleoplasmic speckles varied in different cell types. Heat shock, which inhibits general chromosomal transcription, caused the individual speckles to coalesce into larger but fewer clusters. In extreme cases, only a single large cluster of hsrω-n transcripts localizing to the hsrω locus was seen in each nucleus. In situ immunocytochemical staining using antibodies against heterogenous nuclear RNA binding proteins (hnRNPs) like HRB87F, Hrp40, Hrb57A and S5 revealed that, in all cell types, all the hnRNPs gave a diffuse staining of chromatin areas and in addition, were present as large numbers of speckles. Colocalization studies revealed an absolute colocalization of the hnRNPs and the omega speckles. Heat shock caused all the hnRNPs to cluster together exactly, following the hsr ω-n transcripts. Immunoprecipitation studies using the hnRNP antibodies further demonstrated a physical association of hnRNPs and hsrω transcripts. The omega speckles are distinct from interchromatin granules since nuclear speckles containing serine/arginine-rich SRproteins like SC35 and SRp55 did not colocalize with the omega speckles. The speckled distribution of hnRNPs was completely disrupted in hsrω nullosomics. We conclude that the hsrω-n transcripts play essential structural and functional roles in organizing and establishing the hnRNPcontaining omega speckles and thus regulate the trafficking and availability of hnRNPs and other related RNA binding proteins in the cell nucleus. SUMMARY
153 citations
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TL;DR: The goals of this review are to examine the roles of Hsp70 in cancer and to present strategies targeting HSP70 in the development of cancer therapeutics.
153 citations
Authors
Showing all 12110 results
Name | H-index | Papers | Citations |
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Ashok Kumar | 151 | 5654 | 164086 |
Rajesh Kumar | 149 | 4439 | 140830 |
Prashant Shukla | 131 | 1341 | 85287 |
Sudhir Malik | 130 | 1669 | 98522 |
Vijay P. Singh | 106 | 1699 | 55831 |
Rakesh Agrawal | 105 | 668 | 107569 |
Gautam Sethi | 102 | 425 | 31088 |
Jens Christian Frisvad | 99 | 453 | 31760 |
Sandeep Kumar | 94 | 1563 | 38652 |
E. De Clercq | 90 | 774 | 30296 |
Praveen Kumar | 88 | 1339 | 35718 |
Shyam Sundar | 86 | 614 | 30289 |
Arvind Kumar | 85 | 876 | 33484 |
Padma Kant Shukla | 84 | 1232 | 35521 |
Brajesh K. Singh | 83 | 401 | 24101 |