Bar-Ilan University

About: Bar-Ilan University is a education organization based out in Ramat Gan, Israel. It is known for research contribution in the topics: Population & Poison control. The organization has 12835 authors who have published 34964 publications receiving 995648 citations. The organization is also known as: Bar Ilan University & BIU.

Mother and infant coordinate heart rhythms through episodes of interaction synchrony.

Abstract: a b s t r a c t Animal studies demonstrated the powerful impact of maternal-infant social contact on the infant's physiological systems, yet the online effects of social interactions on the human infant's physiology remain poorly understood. Mothers and their 3-month old infants were observed during face-to-face interactions while cardiac output was collected from mother and child. Micro-analysis of the partners' behavior marked episodes of gaze, affect, and vocal synchrony. Time-series analysis showed that mother and infant coordinate heart rhythms within lags of less than 1 s. Bootstrapping analysis indicated that the concordance between maternal and infant biological rhythms increased significantly during episodes of affect and vocal synchrony compared to non-synchronous moments. Humans, like other mammals, can impact the physiological processes of the attachment partner through the coordination of visuo-affective social signals.

Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light

Abstract: Propionibacterium acnes is a Gram-positive, microaerophilic bacterium that causes skin wounds. It is known to naturally produce high amounts of intracellular porphyrins. The results of the present study confirm that the investigated strain of P. acnes is capable of producing endogenic porphyrins with no need for any trigger molecules. Extracts from growing cultures have demonstrated emission peaks around 612 nm when excited at 405 nm, which are characteristic for porphyrins. Endogenic porphyrins were determined and quantified after their extraction from the bacterial cells by fluorescence intensity and by elution retention time on high-performance liquid chromatography (HPLC). The porphyrins produced by P. acnes are mostly coproporphyrin, as shown by the HPLC elution patterns. Addition of δ-aminolevulinic acid (ALA) enhanced intracellular porphyrin synthesis and higher amounts of coproporphyrin have been found. Eradication of P. acnes by its endogenic porphyrins was examined after illumination with intense blue light at 407–420 nm. The viability of 24 h cultures grown anaerobically in liquid medium was reduced by less than two orders of magnitude when illuminated once with a light dose of 75 J cm−2. Better photodynamic effects were obtained when cultures were illuminated twice or three times consecutively with a light dose of 75 J cm−2 and an interval of 24 h between illuminations. The viability of the culture under these conditions decreased by four orders of magnitude after two illuminations and by five orders of magnitude after three illuminations. When ALA-triggered cultures were illuminated with intense blue light at a light dose of 75 J cm−2 the viability of the treated cultures decreased by seven orders of magnitude. This decrease in viability can occur even after a single exposure of illumination for the indicated light intensity. X-ray microanalysis and transmission electron microscopy revealed structural damages to membranes in the illuminated P. acnes. Illumination of the endogenous coproporphyrin with blue light (407–420 nm) apparently plays a major role in P. acnes photoinactivation. A treatment protocol with a series of several illuminations or illumination after application of ALA may be suitable for curing acne. Treatment by both pathways may overcome the resistance of P. acnes to antibiotic treatment.

Normal families: New perspectives

Abstract: This paper surveys some surprising applications of a lemma characterizing normal families of meromorphic functions on plane domains. These include short and efficient proofs of generalizations of (i) the Picard Theorems, (ii) Gol’dberg’s Theorem (a meromorphic function on C which is the solution of a first-order algebraic differential equation has finite order), and (iii) the Fatou-Julia Theorem (the Julia set of a rational function of degree d ≥ 2 is the closure of the repelling periodic points). We also discuss Bloch’s Principle and provide simple solutions to some problems of Hayman connected with this principle. Over twenty years ago, on the way to a partial explication of the phenomenon known as Bloch’s Principle, I proved a little lemma characterizing normal families of holomorphic and meromorphic functions on plane domains [68]. Over the years, the lemma has grown and, in dextrous hands, proved amazingly versatile, with applications to a wide variety of topics in function theory and related areas. With the renewed interest in normal families (arising largely from the important role they play in complex dynamics), it seems sensible to survey some of the most striking of these applications to the one-variable theory, with the aim of making this technique available to as broad an audience as possible. That is the purpose of this report. One pleasant aspect of the theory is that judicious application of the lemma often leads to proofs which seem almost magical in their brevity. In such cases, we have made no effort to resist the temptation to write out complete proofs. Hardly anything beyond a basic knowledge of function theory is required to understand what follows, so the reader is urged to take courage and plough on through. And now we turn to our tale. 1. Let D be a domain in the complex plane C. We shall be concerned with analytic maps (i.e., meromorphic functions) f : (D, | |R2) → (Ĉ, χ) Received by the editors October 15, 1997, and, in revised form, May 26, 1998. 1991 Mathematics Subject Classification. Primary 30D45; Secondary 30D35, 34A20, 58F23.