Institution
Bethesda Hospital
Healthcare•Ambur, Tamil Nadu, India•
About: Bethesda Hospital is a healthcare organization based out in Ambur, Tamil Nadu, India. It is known for research contribution in the topics: Population & Helicobacter pylori. The organization has 386 authors who have published 472 publications receiving 15193 citations.
Papers published on a yearly basis
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University of Bedfordshire1, Saint Louis University2, University of Naples Federico II3, Cardiff University4, Bethesda Hospital5, Geneva College6, The Chinese University of Hong Kong7, University of Adelaide8, Deakin University9, University of British Columbia10, Sheba Medical Center11, University of Vienna12, Stanford University13
TL;DR: A collaborative Expert Group of the IAGG and EDWPOP and an International Task Force have explored the key issues that affect diabetes in older people using a robust method comprising a Delphi process and an evidence-based review of the literature.
373 citations
TL;DR: There is clearly a need for ongoing community-based support and assistance in dealing with practical difficulties and psychological problems as they are experienced after return to the community.
Abstract: A group of 175 traumatic brain injury (TBI) patients who had undergone intensive rehabilitation at Bethesda Hospital attended a follow-up interview 2 years after injury. The majority of patients had suffered severe TBI. Outcome was documented in ten areas: medical/physical, mobility, activities of daily living (ADLs) accommodation, marital status, leisure and recreation, employment/study, communication, cognition and behaviour. Whilst most patients were physically independent and competent in personal and domestic activities of daily living, a third of the group were still reliant on assistance with community skills and transport, and more than half of those who previously had a job, were not working at 2 years post-injury. Around two-thirds of the sample reported cognitive, behavioural and emotional changes. There is clearly a need for ongoing community-based support and assistance in dealing with practical difficulties and psychological problems as they are experienced after return to the community.
316 citations
Journal Article•
TL;DR: All antral biopsy-based tests, as well as the 13C-urea breath test, are accurate for the diagnosis of H. pylori infection.
263 citations
TL;DR: T-DM1 is particularly effective in eliciting antitumor immunity in patients with early breast cancer and in a HER2-expressing orthotopic tumor model, and it is shown that it can be used in combination therapy.
Abstract: Targeted drug delivery with antibody-drug conjugates such as the HER2-directed ado-trastuzumab emtansine (T-DM1) has emerged as a powerful strategy for cancer therapy. We show that T-DM1 is particularly effective in eliciting antitumor immunity in patients with early breast cancer (WSG-ADAPT trial) and in a HER2-expressing orthotopic tumor model. In the latter, despite primary resistance to immunotherapy, combined treatment with T-DM1 and anti-CTLA-4/PD-1 (cytotoxic T lymphocyte-associated protein-4/programmed cell death protein-1) was curative because it triggered innate and adaptive immunity. Tumor rejection was accompanied by massive T cell infiltration, TH1 (T helper 1) cell polarization, and, notably, a substantial increase in regulatory T cells. Depletion of regulatory T cells resulted in inflammation and tissue damage, implying their essential role in protecting the host during therapy. This study provides insights into the mechanisms of T-DM1's therapeutic activity and a rationale for potential therapeutic combination strategies with immunotherapy.
258 citations
TL;DR: Persisting problems following mild head injury in children are more common in those with previous head injury, preexisting learning difficulties, or neurological, psychiatric, or family problems, and these "at-risk" children should be identified in the emergency department and monitored.
Abstract: Objectives:To investigate outcome in children with mild traumatic head injury (THI) at 1 week and 3 months postinjury and to identify factors associated with persisting problems.Design:Postconcussional symptomatology, behavior ratings, and neuropsychological test performance were examined at 1 week
242 citations
Authors
Showing all 387 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Jennie Ponsford | 73 | 393 | 18379 |
| Peter J. Stern | 53 | 235 | 8622 |
| Roger Hart | 46 | 154 | 7065 |
| Glynda J. Kinsella | 40 | 120 | 5752 |
| Jacinta Douglas | 39 | 180 | 4737 |
| Gabriela Möslein | 36 | 112 | 6057 |
| Pamela Claire Snow | 36 | 142 | 4496 |
| Michael Denkinger | 34 | 147 | 3214 |
| Thomas Daikeler | 30 | 141 | 3309 |
| John Olver | 25 | 103 | 3189 |
| J. C. Thijs | 24 | 46 | 2194 |
| Daniel Navot | 24 | 56 | 2705 |
| Bernd Sanner | 23 | 102 | 2652 |
| Ulrike Nitz | 22 | 98 | 4068 |
| Dries Testelmans | 22 | 92 | 2100 |