Institution
Bethesda Hospital
Healthcare•Ambur, Tamil Nadu, India•
About: Bethesda Hospital is a healthcare organization based out in Ambur, Tamil Nadu, India. It is known for research contribution in the topics: Population & Helicobacter pylori. The organization has 386 authors who have published 472 publications receiving 15193 citations.
Papers published on a yearly basis
Papers
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TL;DR: The optimal approach to management of uncomplicated dyspepsia is dependent on the prevalence of H. pylori among the dyspeptic population, and at the current prevalence rate, 'test and treat', followed by acid suppressive treatment in the case of persisting symptoms, is the most appropriate strategy.
Abstract: Background: Dyspepsia is common in western society. Prompt endoscopy is imperative in all patients with sinister symptoms or if symptoms first appear after the age of 50-55 years, but the optimal management of younger patients with uncomplicated dyspepsia is still open to debate. Methods: The literature on the management of uncomplicated dyspepsia is reviewed and a personal view is presented. Results: Strategies based on non-invasive detection of Helicobacter pylori are probably the most cost-effective. Currently (H. pylori prevalence 30%-40%), a 'test and treat' approach using a non-invasive test to detect H. pylori is likely to be the most efficient first step. If the patient is H. pylori-negative or if symptoms persist after successful H. pylori eradication, empirical treatment with an anti-secretory drug is justified. Endoscopy is reserved for those patients in whom this approach fails. If the prevalence of H. pylori decreases, the positive predictive value of any non-invasive H. pylori test will become too low. A 'test and scope' approach in which a positive test can be confirmed by two or more biopsy-based tests is then more appropriate. At a very low prevalence of H. Pylori in the dyspeptic population, non-invasive testing for H. pylori loses its significance and empirical treatment with an antisecretory drug becomes a rational first step. Conclusions: The optimal approach to management of uncomplicated dyspepsia is dependent on the prevalence of H. pylori among the dyspeptic population. At the current prevalence rate, 'test and treat', followed by acid suppressive treatment in the case of persisting symptoms, is the most appropriate strategy.
10 citations
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TL;DR: Routine use of ultrasound-guided embryo transfer resulted in the rescue of the patient's embryos for cryopreservation, with a resulting ongoing pregnancy.
10 citations
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TL;DR: ADAPT TN compares 12-week neoadjuvant regimens: Carbo vs. Gem combined with Nab-Pac and aims to identify early-response markers for pCR (yPN0 and ypT0/is), which are associated with improved prognosis in TNBC.
Abstract: 1032 Background: Pathological complete response (pCR) is associated with improved prognosis in TNBC, but optimal chemotherapy remains unclear. Neoadjuvant weekly nab-paclitaxel (Nab-Pac) has higher...
10 citations
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TL;DR: In this paper, an investigation of Adult Metachromatic Leukodystrophy in a Dutch family, of which two persons were affected, was described, a 30-year old man showed a conspicious organic brain syndrome, that progressed in two years to a complete dementia.
10 citations
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TL;DR: The case of a 65-year-old man with a radiogenic mandibular non-union after ablative tumour therapy and pre-operative radiation therapy presented with a non- union, vertical distraction in combination with subsequent repeated, stepwise compression and distraction had a positive effect on the consolidation of the regenerate.
9 citations
Authors
Showing all 387 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jennie Ponsford | 73 | 393 | 18379 |
Peter J. Stern | 53 | 235 | 8622 |
Roger Hart | 46 | 154 | 7065 |
Glynda J. Kinsella | 40 | 120 | 5752 |
Jacinta Douglas | 39 | 180 | 4737 |
Gabriela Möslein | 36 | 112 | 6057 |
Pamela Claire Snow | 36 | 142 | 4496 |
Michael Denkinger | 34 | 147 | 3214 |
Thomas Daikeler | 30 | 141 | 3309 |
John Olver | 25 | 103 | 3189 |
J. C. Thijs | 24 | 46 | 2194 |
Daniel Navot | 24 | 56 | 2705 |
Bernd Sanner | 23 | 102 | 2652 |
Ulrike Nitz | 22 | 98 | 4068 |
Dries Testelmans | 22 | 92 | 2100 |