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Showing papers by "BIA Separations (Slovenia) published in 2010"


Journal ArticleDOI
TL;DR: Methacrylate monoliths (Convective Interaction Media monolithic columns) were applied for the purification of Staphylococcus aureus phages VDX-10 from bacterial lysate, resulting in more than 99% of host cell DNA and more than 90% of proteins were removed, with 60% recovery of viable phages.

71 citations


Journal ArticleDOI
23 Feb 2010-Vaccine
TL;DR: A pDNA purification process designed on two different CIM monolithic columns, based on anion-exchange (AEX) chromatography and hydrophobic interaction chromatography (HIC) chemistry, found to be reproducible, scalable, and exhibits high productivity.

64 citations


Patent
28 Oct 2010
TL;DR: In this article, a sample distribution device for distribution of samples in liquid chromatographs comprises a sample supply channel arranged in a holding element, with a receiving chamber, and a distributing element is arranged.
Abstract: A sample distribution device for distribution of samples in liquid chromatographs comprises a sample supply channel arranged in a holding element. The holding element includes a receiving chamber, with the sample supply channel leading into the receiving chamber. Internally of receiving chamber, a distributing element is arranged. The passage openings for passage of the sample are formed by an inner side of the receiving chamber and by an outer side of the distributing element; preferably, for this purpose, the distributing element has recesses on the outer side. The sample distribution device is arranged in a device for liquid chromatography, wherein the sample will flow radially through the chromatography resin.

1 citations


Patent
24 Mar 2010
TL;DR: In this article, a sample distribution device for distribution of samples in liquid chromatographs comprises a sample supply channel (10) arranged in a holding element (12), the holding element includes a receiving chamber (14), with the sample supply channels leading into the receiving chamber.
Abstract: A sample distribution device for distribution of samples in liquid chromatographs comprises a sample supply channel (10) arranged in a holding element (12). The holding element (12) includes a receiving chamber (14), with the sample supply channel (10) leading into the receiving chamber (14). Internally of receiving chamber (14), a distributing element (16) is arranged. The passage openings (22) for passage of the sample are formed by an inner side (18) of the receiving chamber (14) and by an outer side (20) of the distributing element (16); preferably, for this purpose, the distributing element (16) has recesses on the outer side. The sample distribution device is arranged in a device for liquid chromatography, wherein the sample will flow radially through the chromatography resin (44).