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Institution

BIA Separations (Slovenia)

CompanyLjubljana, Slovenia
About: BIA Separations (Slovenia) is a company organization based out in Ljubljana, Slovenia. It is known for research contribution in the topics: Monolithic HPLC column & Monolith. The organization has 84 authors who have published 152 publications receiving 4883 citations.


Papers
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Journal ArticleDOI
TL;DR: In this article, the effects of zeolite structure and surface chemistry on films dye removal kinetics from a standardised rinsing bath were investigated for up to 140 min at room temperature and using 0.1 g/l of dye concentration, depending on the film-tobath weight-to-volume ratios (from 1:10 to 1:1000).
Abstract: Water stable, flexible and ecological acceptance composite films were prepared by the solvent casting process using native, dealuminated (treated with HCl to affect the surface chemistry and pore structure) and/or surface modified (coated with a cationic surfactant PDADM of different molecular weights) H-ZSM-5 type zeolite of different shapes (spherical vs. rod) and Si/Al ratios (P26 vs. P371) as adsorbents and cellulose nanofibrils (CNFs) as a networking matrix (in a weight ratio of 4:1). The films were tested for removal of the black anionic reactive dye with the highest bleeding effect at the first rinsing cycle of textile laundering. The effects of zeolite structure and surface chemistry on films dye’ removal kinetics from a standardised rinsing bath were investigated for up to 140 min at room temperature and using 0.1 g/l of dye concentration, depending on the film-to-bath weight-to-volume ratios (from 1:10 to 1:1000), thus simulating different rinsing conditions. The results show that up to 80 % of the dye was removed in the first 20 min in the lowest weight-to-volume ratio (1:10), fitting the Langmuir isotherm, and the process followed the pseudo-second order kinetic, yielding a multi-layer adsorption mechanism with a monolayer capacity of ~11 mg/g and ~21 vs. ~30 mg/g by films prepared from native or HCltreated and PDADMA100 vs. PDADMA400 coated P371 zeolites, respectively. Such efficacy was due to the more densely and fully surface-covered longitudinal P371 with PDADM400, given the huge electrostatic attraction sites for dye molecules, compared to the partly interpenetrated PDADM into relatively larger pore-sized (~450 nm vs. 220 nm) of P26. The filtration performance of the films was also examined, be used for the removal of the dye from the rinsing bath, released from the washing drum. An ultra-high flux rate (11.000 kL/m2 h MPa) with 45 % of dye removal efficacy and capacity of ~24 mg/g was provided by films prepared from spherical and aggregated P26PDADMA-400, showing its high potential also as a filter membrane.

9 citations

Journal ArticleDOI
TL;DR: A new method, suitable for porous media, is presented here to determine the surface energy and its Lifshitz-van-der-Waals, Lewis acid and Lewis base contributions.

9 citations

Journal ArticleDOI
19 Feb 2021-Genes
TL;DR: In this paper, the authors designed a custom droplet digital PCR (ddPCR) for quantification and quality control of cfDNA isolated from serum for colorectal cancer (CRC) patients.
Abstract: Liquid biopsy and cell-free DNA (cfDNA) show great promise in cancer diagnostics. In this study, we designed a custom droplet digital PCR (ddPCR) assay for the quantification and quality control of cfDNA isolated from serum. The assay was validated on a group of locally advanced colorectal cancer (CRC) patients and two control groups—patients with hemorrhoids and healthy individuals. The assay shows a high correlation with Qubit measurement (r = 0.976) but offers a higher dynamic range. Mean concentrations of cfDNA were 12.36 ng/µL, 5.17 ng/µL, and 0.29 ng/µL for CRC, hemorrhoid patients, and healthy controls, respectively. The quality of cfDNA was assessed with the measurement of B-cell DNA contamination. On a subset of CRC patients, we compared the mutation status on KRAS (G12A, G12D, G12V, G13D) and BRAF (V600E) genes in the primary tumor and cfDNA isolated from the serum. A total of 70.6% of primary tumor samples were mutated, and the mean fractional abundance of mutations was 9.50%. The matching serum samples were mutated in 38% cases with an average fractional abundance of 0.23%. We conclude that any decisions based solely on the amount of cfDNA present in patient serum must be interpreted carefully and in the context of co-morbidities. This study explores the potential of ddPCR somatic mutations detection from liquid biopsy as a supplement to tissue biopsy in targeted personalized CRC patient management.

9 citations

Journal ArticleDOI
TL;DR: The combined approach of ELISA and CIM® monolith-supported extraction was successfully tested also for the detection of protein in real-case paint layers, for the first time in the field of Cultural Heritage.

8 citations


Authors

Showing all 84 results

NameH-indexPapersCitations
Aleš Štrancar381223748
Djuro Josic361774580
Aleš Podgornik36903274
Thomas Muster33677766
Miloš Barut23451500
Matjaž Peterka17321222
Petra Kramberger1423642
Janez Jančar1114425
Jana Vidič1019686
Nika Lendero Krajnc1019395
Urh Černigoj925267
Rok Košir914456
Peter Brne88330
Marko Banjac710206
Lidija Urbas78241
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20219
20203
20193
20184
201712
20168