BIA Separations (Slovenia)

About: BIA Separations (Slovenia) is a company organization based out in Ljubljana, Slovenia. It is known for research contribution in the topics: Monolithic HPLC column & Monolith. The organization has 84 authors who have published 152 publications receiving 4883 citations.

Sample distribution device of samples in liquid chromatographs

Abstract: A sample distribution device for distribution of samples in liquid chromatographs comprises a sample supply channel (10) arranged in a holding element (12). The holding element (12) includes a receiving chamber (14), with the sample supply channel (10) leading into the receiving chamber (14). Internally of receiving chamber (14), a distributing element (16) is arranged. The passage openings (22) for passage of the sample are formed by an inner side (18) of the receiving chamber (14) and by an outer side (20) of the distributing element (16); preferably, for this purpose, the distributing element (16) has recesses on the outer side. The sample distribution device is arranged in a device for liquid chromatography, wherein the sample will flow radially through the chromatography resin (44).

So3 chromatography for use in a method for virus purification

Abstract: The present invention refers to a process for purifying virus particles from cell culture, comprising the steps of subjecting the cell culture to centrifugation to get a supernatant fraction of virus particles, incubating said fraction with a nuclease, diluting the fraction with low conductivity buffer, subjecting said diluted fraction to a SO3 chromatography step, performing a washing step with low conductivity buffer, and eluting virus particles.