Institution
Boise State University
Education•Boise, Idaho, United States•
About: Boise State University is a education organization based out in Boise, Idaho, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 3698 authors who have published 8664 publications receiving 210163 citations. The organization is also known as: BSU & Boise State.
Topics: Population, Poison control, Educational technology, Snow, Zircon
Papers published on a yearly basis
Papers
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TL;DR: In this article, a high-resolution δ13Ccarb chemostratigraphic framework from latest Guadalupian to earliest Triassic time was presented, calibrated with high resolution conodont biostratigraphy and high-precision geochronology.
125 citations
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TL;DR: In this paper, a GIS-based multi-criteria solar project siting study conducted in the southwestern United States with a unique social preference component is presented, where proximity raster layers were derived from features including roads, power lines, and rivers then overlain with 10 × 10 m raster terrain datasets including slope and potential irradiance to produce a high resolution map showing solar energy potential from “poor” to “excellent” for high potential counties across the southwest United States.
124 citations
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TL;DR: Results indicate that the novel FITC encapsulated multifunctional particles with nanoscale ZnO surface layer can be used as smart nanostructures for particle tracking, cell imaging, antibacterial treatments and cancer therapy.
Abstract: Fluorescein isothiocyanate (FITC)-encapsulated SiO(2) core-shell particles with a nanoscale ZnO finishing layer have been synthesized for the first time as multifunctional "smart" nanostructures. Detailed characterization studies confirmed the formation of an outer ZnO layer on the SiO(2)-FITC core. These approximately 200 nm sized particles showed promise toward cell imaging and cellular uptake studies using the bacterium Escherichia coli and Jurkat cancer cells, respectively. The FITC encapsulated ZnO particles demonstrated excellent selectivity in preferentially killing Jurkat cancer cells with minimal toxicity to normal primary immune cells (18% and 75% viability remaining, respectively, after exposure to 60 microg/ml) and inhibited the growth of both gram-positive and gram-negative bacteria at concentrations > or =250-500 microg/ml (for Staphylococcus aureus and Escherichia coli, respectively). These results indicate that the novel FITC encapsulated multifunctional particles with nanoscale ZnO surface layer can be used as smart nanostructures for particle tracking, cell imaging, antibacterial treatments and cancer therapy.
124 citations
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TL;DR: The detection of aggregates in vitro strongly suggests that deamidation may contribute to protein aggregation in the lens and a potential mechanism may include decreased stability and/or altered interactions with other β‐subunits.
Abstract: Protein aggregation is a hallmark of several neurodegenerative diseases and also of cataracts. The major proteins in the lens of the eye are crystallins, which accumulate throughout life and are extensively modified. Deamidation is the major modification in the lens during aging and cataracts. Among the crystallins, the βA3-subunit has been found to have multiple sites of deamidation associated with the insoluble proteins in vivo. Several sites were predicted to be exposed on the surface of βA3 and were investigated in this study. Deamidation was mimicked by site-directed mutagenesis at Q42 and N54 on the N-terminal domain, N133 and N155 on the C-terminal domain, and N120 in the peptide connecting the domains. Deamidation altered the tertiary structure without disrupting the secondary structure or the dimer formation of βA3. Deamidations in the C-terminal domain and in the connecting peptide decreased stability to a greater extent than deamidations in the N-terminal domain. Deamidation at N54 and N155 also disrupted the association with the βB1-subunit. Sedimentation velocity experiments integrated with high-resolution analysis detected soluble aggregates at 15%–20% in all deamidated proteins, but not in wild-type βA3. These aggregates had elevated frictional ratios, suggesting that they were elongated. The detection of aggregates in vitro strongly suggests that deamidation may contribute to protein aggregation in the lens. A potential mechanism may include decreased stability and/or altered interactions with other β-subunits. Understanding the role of deamidation in the long-lived crystallins has important implications in other aggregation diseases.
123 citations
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TL;DR: In this paper, an extended Kays and Crawford (Convective Heat and Mass Transfer, 3rd edn. McGraw-Hill, New York, 1993) turbulent Prandtl number model is used for accurately predicting the heat transfer for liquid metal flows.
123 citations
Authors
Showing all 3902 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jeffrey G. Andrews | 110 | 562 | 63334 |
Zhu Han | 109 | 1407 | 48725 |
Brian R. Flay | 89 | 325 | 26390 |
Jeffrey W. Elam | 83 | 435 | 24543 |
Pramod K. Varshney | 79 | 894 | 30834 |
Scott Fendorf | 79 | 244 | 21035 |
Gregory F. Ball | 76 | 342 | 21193 |
Yan Wang | 72 | 1253 | 30710 |
David C. Dunand | 72 | 527 | 19212 |
Juan Carlos Diaz-Velez | 64 | 334 | 14252 |
Michael K. Lindell | 62 | 186 | 19865 |
Matthew J. Kohn | 62 | 164 | 13741 |
Maged Elkashlan | 61 | 294 | 14736 |
Bernard Yurke | 58 | 242 | 17897 |
Miguel Ferrer | 58 | 478 | 11560 |