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Institution

Boston University

EducationBoston, Massachusetts, United States
About: Boston University is a education organization based out in Boston, Massachusetts, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 48688 authors who have published 119622 publications receiving 6276020 citations. The organization is also known as: BU & Boston U.


Papers
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Journal ArticleDOI
TL;DR: In this article, a randomized controlled trial was conducted to evaluate the clinical effect of implementing RED among patients admitted to a general medical service and found that a nurse discharge advocate and clinical pharmacist working together to coordinate hospital discharge, educate patients, and reconcile medications led to fewer follow-up emergency visits and rehospitalizations than usual care alone.
Abstract: One in 5 hospitalizations is complicated by postdischarge adverse events (1, 2), some of which may lead to preventable emergency department visits or readmissions. Despite this finding, hospital discharge procedures have not been standardized (3). In addition, the declining presence of primary care providers (PCPs) in hospitals has not been adequately accompanied by systems to ensure that patient data are transferred to subsequent caregivers (4, 5). For example, discharge summaries frequently lack critical data and are not sent to the PCP in a timely fashion (6, 7), resulting in outpatient clinicians being unaware of test results that were pending at discharge (8) and evaluations that were scheduled to be done after discharge not being completed (9). Similarly, patients are often left unprepared at discharge; many do not understand their discharge medications and cannot recall their chief diagnoses (10). With more than 32 million adult discharges in the United States each year (11), these deficiencies in the transition of care increase illness, unnecessary hospital utilization, and cost. Some peridischarge interventions have shown a reduction in hospital readmission rates and cost (12-14), emergency department visits (15), and postdischarge adverse events (16), whereas some have shown little or no effect (17-20). Peridischarge interventions have also shown improved PCP follow-up and outpatient work-ups (21) and higher patient satisfaction (15). Most of these studies have focused on specific diagnoses (14, 22, 23) or highly selected populations, such as geriatric adults (12, 13, 19, 24). Some have focused on specific aspects of the discharge, such as increasing access to primary care follow-up (25), connecting with transitional nursing services (26), or improving patients′ ability to advocate for themselves after discharge (12). To date, no study has evaluated a standardized discharge intervention that includes patient education, comprehensive discharge planning, and postdischarge telephone reinforcement in a general medical population. Context Emergency department visits and rehospitalizations are common after hospital discharge. Contribution This trial demonstrated that a nurse discharge advocate and clinical pharmacist working together to coordinate hospital discharge, educate patients, and reconcile medications led to fewer follow-up emergency visits and rehospitalizations than usual care alone. Caution The trial was conducted at a single center, and not all eligible patients were enrolled. Implication A systematic approach to hospital discharges can reduce unnecessary health service use. —The Editors In 2004, we began an in-depth examination of hospital discharge, for which we designed a package of services to minimize discharge failures—a process called reengineered discharge (RED) (Table 1) (3, 27). We did a randomized, controlled trial to evaluate the clinical effect of implementing RED among patients admitted to a general medical service. Table 1 Components of Reengineered Hospital Discharge

1,382 citations

Journal ArticleDOI
Thomas J. Wang1, Feng Zhang2, J. Brent Richards, Bryan Kestenbaum3, Joyce B. J. van Meurs4, Diane J. Berry5, Douglas P. Kiel, Elizabeth A. Streeten6, Claes Ohlsson7, Daniel L. Koller8, Leena Peltonen9, Leena Peltonen10, Jason D. Cooper2, Paul F. O'Reilly11, Denise K. Houston12, Nicole L. Glazer3, Liesbeth Vandenput7, Munro Peacock8, Julia Shi6, Fernando Rivadeneira4, Mark I. McCarthy13, Mark I. McCarthy14, Mark I. McCarthy15, Pouta Anneli, Ian H. de Boer3, Massimo Mangino2, Bernet S. Kato2, Deborah J. Smyth7, Sarah L. Booth16, Paul F. Jacques16, Greg L. Burke12, Mark O. Goodarzi17, Ching-Lung Cheung18, Myles Wolf19, Kenneth Rice3, David Goltzman2, Nick Hidiroglou20, Martin Ladouceur, Nicholas J. Wareham7, Lynne J. Hocking16, Deborah J. Hart2, Nigel K Arden14, Cyrus Cooper14, Suneil Malik21, William D. Fraser22, Anna Liisa Hartikainen2, Guangju Zhai2, Helen M. Macdonald2, Nita G. Forouhi23, Ruth J. F. Loos23, David M. Reid24, Alan Hakim, Elaine M. Dennison25, Yongmei Liu9, Chris Power5, Helen Stevens2, Laitinen Jaana21, Ramachandran S. Vasan26, Nicole Soranzo27, Nicole Soranzo10, Jörg Bojunga28, Bruce M. Psaty3, Mattias Lorentzon7, Tatiana Foroud8, Tamara B. Harris9, Albert Hofman4, John-Olov Jansson11, Jane A. Cauley29, André G. Uitterlinden, Quince Gibson, Marjo-Riitta Järvelin, David Karasik, David S. Siscovick3, Michael J. Econs8, Stephen B. Kritchevsky22, Jose C. Florez, John A. Todd7, Josée Dupuis26, Elina Hyppönen5, Tim D. Spector27 
TL;DR: In this article, a genome-wide association study of 25-hydroxyvitamin D concentrations in 33,996 individuals of European descent from 15 cohorts was conducted to identify common genetic variants affecting vitamin D concentrations and risk of insufficiency.

1,381 citations

Proceedings Article
05 Dec 2016
TL;DR: The authors showed that even word embeddings trained on Google News articles exhibit female/male gender stereotypes to a disturbing extent, which raises concerns because their widespread use often tends to amplify these biases.
Abstract: The blind application of machine learning runs the risk of amplifying biases present in data. Such a danger is facing us with word embedding, a popular framework to represent text data as vectors which has been used in many machine learning and natural language processing tasks. We show that even word embeddings trained on Google News articles exhibit female/male gender stereotypes to a disturbing extent. This raises concerns because their widespread use, as we describe, often tends to amplify these biases. Geometrically, gender bias is first shown to be captured by a direction in the word embedding. Second, gender neutral words are shown to be linearly separable from gender definition words in the word embedding. Using these properties, we provide a methodology for modifying an embedding to remove gender stereotypes, such as the association between the words receptionist and female, while maintaining desired associations such as between the words queen and female. Using crowd-worker evaluation as well as standard benchmarks, we empirically demonstrate that our algorithms significantly reduce gender bias in embeddings while preserving the its useful properties such as the ability to cluster related concepts and to solve analogy tasks. The resulting embeddings can be used in applications without amplifying gender bias.

1,379 citations

Journal ArticleDOI
TL;DR: Given the incomplete response of many patients to a GFD-free diet as well as the difficulty of adherence to the GFD over the long term, development of new effective therapies for symptom control and reversal of inflammation and organ damage are needed.

1,379 citations

Journal ArticleDOI
TL;DR: It is suggested that a quantitative loss in muscle CSA is a major contributor to the decrease in muscle strength seen with advancing age and accounts for 90% of the variability in strength at T2.
Abstract: The present study examines age-related changes in skeletal muscle size and function after 12 yr. Twelve healthy sedentary men were studied in 1985–86 (T1) and nine (initial mean age 65.4 ± 4.2 yr) ...

1,378 citations


Authors

Showing all 49233 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Robert Langer2812324326306
Meir J. Stampfer2771414283776
Ronald C. Kessler2741332328983
JoAnn E. Manson2701819258509
Albert Hofman2672530321405
George M. Whitesides2401739269833
Paul M. Ridker2331242245097
Eugene Braunwald2301711264576
Ralph B. D'Agostino2261287229636
David J. Hunter2131836207050
Daniel Levy212933194778
Christopher J L Murray209754310329
Tamara B. Harris2011143163979
André G. Uitterlinden1991229156747
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023223
2022810
20216,942
20206,837
20196,120
20185,593